Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell

Detalhes bibliográficos
Autor(a) principal: Queiroz, Alice Soares de
Data de Publicação: 2023
Outros Autores: Oliveira, Daniel Lacerda, Lima, Axel Jhonantam Oliveira, Lourenzoni, Marcos Roberto
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/57951
Resumo: Apresentador do material: Alice Soares de Queiroz Tipo de material apresentado: Pôster
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spelling Queiroz, Alice Soares deOliveira, Daniel LacerdaLima, Axel Jhonantam OliveiraLourenzoni, Marcos Roberto2023-04-24T19:06:19Z2023-04-24T19:06:19Z2023QUEIROZ, A. S. de et al. Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICALS, 7., 2023, Rio de Janeiro. Annals of the Symposium: building pathways to accelerated the development of the national tecnhnological innovation ecosystem. Rio de Janeiro: Instituto de Tecnologia em Imunobiológicos, 2023. p. 46.https://www.arca.fiocruz.br/handle/icict/5795110.35259/isi.2023_57951Apresentador do material: Alice Soares de Queiroz Tipo de material apresentado: PôsterUniversidade Federal do Ceará. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Fortaleza, CE, Brasil.Universidade Federal do Ceará. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Fiocruz Ceará. Eusébio, CE, Brasil.engCAR anti-CD22scFv from M971Simulação de Dinâmica MolecularCAR anti-CD22scFv from M971Molecular DynamicsSimulação de Dinâmica MolecularStudy, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cellinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/57951/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALAnais7thISI2023_46.pdfAnais7thISI2023_46.pdfapplication/pdf183697https://www.arca.fiocruz.br/bitstream/icict/57951/2/Anais7thISI2023_46.pdf6f0fa4114d081be3e6e33961ea1bb6cdMD52icict/579512023-04-24 16:07:46.227oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-04-24T19:07:46Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
title Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
spellingShingle Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
Queiroz, Alice Soares de
CAR anti-CD22
scFv from M971
Simulação de Dinâmica Molecular
CAR anti-CD22
scFv from M971
Molecular Dynamics
Simulação de Dinâmica Molecular
title_short Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
title_full Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
title_fullStr Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
title_full_unstemmed Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
title_sort Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell
author Queiroz, Alice Soares de
author_facet Queiroz, Alice Soares de
Oliveira, Daniel Lacerda
Lima, Axel Jhonantam Oliveira
Lourenzoni, Marcos Roberto
author_role author
author2 Oliveira, Daniel Lacerda
Lima, Axel Jhonantam Oliveira
Lourenzoni, Marcos Roberto
author2_role author
author
author
dc.contributor.author.fl_str_mv Queiroz, Alice Soares de
Oliveira, Daniel Lacerda
Lima, Axel Jhonantam Oliveira
Lourenzoni, Marcos Roberto
dc.subject.other.en_US.fl_str_mv CAR anti-CD22
scFv from M971
Simulação de Dinâmica Molecular
topic CAR anti-CD22
scFv from M971
Simulação de Dinâmica Molecular
CAR anti-CD22
scFv from M971
Molecular Dynamics
Simulação de Dinâmica Molecular
dc.subject.en.en_US.fl_str_mv CAR anti-CD22
scFv from M971
Molecular Dynamics
dc.subject.decs.en_US.fl_str_mv Simulação de Dinâmica Molecular
description Apresentador do material: Alice Soares de Queiroz Tipo de material apresentado: Pôster
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-04-24T19:06:19Z
dc.date.available.fl_str_mv 2023-04-24T19:06:19Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.citation.fl_str_mv QUEIROZ, A. S. de et al. Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICALS, 7., 2023, Rio de Janeiro. Annals of the Symposium: building pathways to accelerated the development of the national tecnhnological innovation ecosystem. Rio de Janeiro: Instituto de Tecnologia em Imunobiológicos, 2023. p. 46.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/57951
dc.identifier.doi.none.fl_str_mv 10.35259/isi.2023_57951
identifier_str_mv QUEIROZ, A. S. de et al. Study, by Molecular Dynamics simulation, of structural determinants of single-chain M971 antibody fragments for an anti-CD22 CAR-T cell. In: INTERNATIONAL SYMPOSIUM ON IMMUNOBIOLOGICALS, 7., 2023, Rio de Janeiro. Annals of the Symposium: building pathways to accelerated the development of the national tecnhnological innovation ecosystem. Rio de Janeiro: Instituto de Tecnologia em Imunobiológicos, 2023. p. 46.
10.35259/isi.2023_57951
url https://www.arca.fiocruz.br/handle/icict/57951
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/57951/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/57951/2/Anais7thISI2023_46.pdf
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