Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis

Detalhes bibliográficos
Autor(a) principal: Batista-da-Silva, Amanda de Araujo
Data de Publicação: 2023
Outros Autores: Moraes, Camila Barros, Bozza, Helena Rodrigues, Bastos, Leonardo dos Santos Lourenço, Ranzani, Otavio T., Hamacher, Silvio, Bozza, Fernando Augusto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1136/bmjgh-2022-009997
Texto Completo: https://www.arca.fiocruz.br/handle/icict/59117
Resumo: Collaborators Comitê Gestor (steering committee) Conexão Saúde is composed of Luna Arouca (Redes da Maré), Valcler Rangel Fernandes (FIOCRUZ), Sabine Zink Bolonhini (SAS Brasil), Eduardo Pádua (União Rio), Andre Lima (Conselho Comunitario de Manguinhos) and Fernando Bozza (FIOCRUZ and Dados do Bem).
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spelling Batista-da-Silva, Amanda de AraujoMoraes, Camila BarrosBozza, Helena RodriguesBastos, Leonardo dos Santos LourençoRanzani, Otavio T.Hamacher, SilvioBozza, Fernando Augusto2023-06-22T01:21:03Z2023-06-22T01:21:03Z2023BATISTA-DA-SILVA, Amanda de Araujo et al. Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis. BMJ Global Health, v. 8, n. 5, p. 1-12, May 2023.2059-7908https://www.arca.fiocruz.br/handle/icict/5911710.1136/bmjgh-2022-0099972059-7908Collaborators Comitê Gestor (steering committee) Conexão Saúde is composed of Luna Arouca (Redes da Maré), Valcler Rangel Fernandes (FIOCRUZ), Sabine Zink Bolonhini (SAS Brasil), Eduardo Pádua (União Rio), Andre Lima (Conselho Comunitario de Manguinhos) and Fernando Bozza (FIOCRUZ and Dados do Bem).Ethics approval This study involves human participants and was approved by National Research Ethics Committee (IRB/CONEP) (CAAE - 44180921.5.0000.5249 and 44180821.1.0000.5249).The Conexão Saude was supported by an unrestricted grant from Todos Pela Saúde fund. This work is part of the Grand Challenges ICODA pilot initiative, delivered by Health Data Research UK and funded by the Bill & Melinda Gates Foundation and the Minderoo Foundation. This study was supported by the National Council for Scientific and Technological Development (CNPq), the Coordination for the Improvement of Higher Education Personnel (CAPES) - Finance Code 001, Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro (FAPERJ), the Pontifical Catholic University of Rio de Janeiro and the Oswaldo Cruz Foundation (FIOCRUZ). OTR acknowledges support from the grant CEX2018-000806-S funded by MCIN/AEI/ 10.13039/501100011033, and support from the Generalitat de Catalunya through the CERCA Program. The funders had no role in study design, data collection, and analysis, decision to publish, or manuscript preparation. The findings and conclusions in this manuscript reflect the opinions of the authors alone.Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil / Pontifical Catholic University of Rio de Janeiro. Tecgraf Institute. Rio de Janeiro, RJ, Brazil.Associação Redes de Desenvolvimento da Maré. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil.Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil / Pontifical Catholic University of Rio de Janeiro. Tecgraf Institute. Rio de Janeiro, RJ, Brazil.Barcelona Institute for Global Health. Barcelona, Spain / University of São Paulo Hospital of Clinics. São Paulo, SP, Brazil.Pontifical Catholic University of Rio de Janeiro. Department of Industrial Engineering. Rio de Janeiro, RJ, Brazil / Pontifical Catholic University of Rio de Janeiro. Tecgraf Institute. Rio de Janeiro, RJ, Brazil.D'Or Institute of Research and Education. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectious Diseases Evandro Chagas. Rio de Janeiro, RJ, Brazil.Introduction: Few community-based interventions addressing the transmission control and clinical management of COVID-19 cases have been reported, especially in poor urban communities from low-income and middle-income countries. Here, we analyse the impact of a multicomponent intervention that combines community engagement, mobile surveillance, massive testing and telehealth on COVID-19 cases detection and mortality rates in a large vulnerable community (Complexo da Maré) in Rio de Janeiro, Brazil. Methods: We performed a difference-in-differences (DID) analysis to estimate the impact of the multicomponent intervention in Maré, before (March-August 2020) and after the intervention (September 2020 to April 2021), compared with equivalent local vulnerable communities. We applied a negative binomial regression model to estimate the intervention effect in weekly cases and mortality rates in Maré. Results: Before the intervention, Maré presented lower rates of reported COVID-19 cases compared with the control group (1373 vs 1579 cases/100 000 population), comparable mortality rates (309 vs 287 deaths/100 000 population) and higher case fatality rates (13.7% vs 12.2%). After the intervention, Maré displayed a 154% (95% CI 138.6% to 170.4%) relative increase in reported case rates. Relative changes in reported death rates were -60% (95% CI -69.0% to -47.9%) in Maré and -28% (95% CI -42.0% to -9.8%) in the control group. The case fatality rate was reduced by 77% (95% CI -93.1% to -21.1%) in Maré and 52% (95% CI -81.8% to -29.4%) in the control group. The DID showed a reduction of 46% (95% CI 17% to 65%) of weekly reported deaths and an increased 23% (95% CI 5% to 44%) of reported cases in Maré after intervention onset. Conclusion: An integrated intervention combining communication, surveillance and telehealth, with a strong community engagement component, could reduce COVID-19 mortality and increase case detection in a large vulnerable community in Rio de Janeiro. These findings show that investment in community-based interventions may reduce mortality and improve pandemic control in poor communities from low-income and middle-income countries.engBMJ Publishing Group LtdEffectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCOVID-19Control strategiesInfectionsDiseasesDisordersInjuriesIntervention studyPublic healthinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.en_US.fl_str_mv Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
title Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
spellingShingle Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
Batista-da-Silva, Amanda de Araujo
COVID-19
Control strategies
Infections
Diseases
Disorders
Injuries
Intervention study
Public health
title_short Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
title_full Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
title_fullStr Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
title_full_unstemmed Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
title_sort Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis
author Batista-da-Silva, Amanda de Araujo
author_facet Batista-da-Silva, Amanda de Araujo
Moraes, Camila Barros
Bozza, Helena Rodrigues
Bastos, Leonardo dos Santos Lourenço
Ranzani, Otavio T.
Hamacher, Silvio
Bozza, Fernando Augusto
author_role author
author2 Moraes, Camila Barros
Bozza, Helena Rodrigues
Bastos, Leonardo dos Santos Lourenço
Ranzani, Otavio T.
Hamacher, Silvio
Bozza, Fernando Augusto
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Batista-da-Silva, Amanda de Araujo
Moraes, Camila Barros
Bozza, Helena Rodrigues
Bastos, Leonardo dos Santos Lourenço
Ranzani, Otavio T.
Hamacher, Silvio
Bozza, Fernando Augusto
dc.subject.en.en_US.fl_str_mv COVID-19
Control strategies
Infections
Diseases
Disorders
Injuries
Intervention study
Public health
topic COVID-19
Control strategies
Infections
Diseases
Disorders
Injuries
Intervention study
Public health
description Collaborators Comitê Gestor (steering committee) Conexão Saúde is composed of Luna Arouca (Redes da Maré), Valcler Rangel Fernandes (FIOCRUZ), Sabine Zink Bolonhini (SAS Brasil), Eduardo Pádua (União Rio), Andre Lima (Conselho Comunitario de Manguinhos) and Fernando Bozza (FIOCRUZ and Dados do Bem).
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-06-22T01:21:03Z
dc.date.available.fl_str_mv 2023-06-22T01:21:03Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BATISTA-DA-SILVA, Amanda de Araujo et al. Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis. BMJ Global Health, v. 8, n. 5, p. 1-12, May 2023.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/59117
dc.identifier.issn.en_US.fl_str_mv 2059-7908
dc.identifier.doi.none.fl_str_mv 10.1136/bmjgh-2022-009997
dc.identifier.eissn.none.fl_str_mv 2059-7908
identifier_str_mv BATISTA-DA-SILVA, Amanda de Araujo et al. Effectiveness of a multicomponent intervention to face the COVID-19 pandemic in Rio de Janeiro's favelas: difference-in-differences analysis. BMJ Global Health, v. 8, n. 5, p. 1-12, May 2023.
2059-7908
10.1136/bmjgh-2022-009997
url https://www.arca.fiocruz.br/handle/icict/59117
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMJ Publishing Group Ltd
publisher.none.fl_str_mv BMJ Publishing Group Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/59117/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/59117/2/ve_Amanda_Batista-da-Silva_etal_INI_2023.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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