A next-generation proteome array for Schistosoma mansoni

Detalhes bibliográficos
Autor(a) principal: Assis, Rafael Ramiro de
Data de Publicação: 2016
Outros Autores: Ludolf, Fernanda, Nakajima, Rie, Jasinskas, Al, Oliveira, Guilherme Correa de, Felgner, Philip L., Jangola, Soraya Torres Gaze, Loukas, Alex, LoVerde, Philip T., Bethony, Jeffrey Michael, Oliveira, Rodrigo Correa de, Silva, Carlos Eduardo Calzavara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15989
Resumo: 2021-01-01
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spelling Assis, Rafael Ramiro deLudolf, FernandaNakajima, RieJasinskas, AlOliveira, Guilherme Correa deFelgner, Philip L.Jangola, Soraya Torres GazeLoukas, AlexLoVerde, Philip T.Bethony, Jeffrey MichaelOliveira, Rodrigo Correa deSilva, Carlos Eduardo Calzavara2016-09-28T17:58:58Z2016-09-28T17:58:58Z2016ASSIS, Rafael Ramiro de Assis, et al. A next-generation proteome array for Schistosoma mansoni. Int J Parasitol., v. 46, n. 7, p. 411-5, 2016.0020-7519https://www.arca.fiocruz.br/handle/icict/1598910.1016/j.ijpara.2016.04.001engElsevier Ltd.anticorposproteomesAntibody signatureProtein microarrayProteomeSchistosoma mansoniA next-generation proteome array for Schistosoma mansoniinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2021-01-01Fundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil/ University of California. School of Medicine. Division of Infectious Disease. Protein Microarray Laboratory. Irvine, CA, USAUniversidade Federal de Minas Gerais. Faculdade de Medicina. Infectologia e Medicina Tropical. Belo Horizonte, MG, BrasilUniversity of California. School of Medicine. Division of Infectious Disease. Protein Microarray Laboratory. Irvine, CA, USAUniversity of California. School of Medicine. Division of Infectious Disease. Protein Microarray Laboratory. Irvine, CA, USAVale Technology Institute of Sustainable Development. Belém, PA, BrazilUniversity of California. School of Medicine. Division of Infectious Disease. Protein Microarray Laboratory. Irvine, CA, USAFundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilJames Cook University. Australian Institute of Tropical Health & Medicine. Centre for Biodiscovery and Molecular Development of Therapeutics. Cairns, QLD, AustraliaUniversity of Texas Health Science Center. School of Medicine. Departments of Biochemistry and Pathology. San Antonio, TX , USAFundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil/The George Washington University. School of Medicine and Health Science. Department of Microbiology, Immunology, and Tropical Medicine. Washington, DC, USAFundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil/ University of California. School of Medicine. Division of Infectious Disease. Protein Microarray Laboratory. Irvine, CA, USAA proteome microarray consisting of 992 Schistosoma mansoni proteins was produced and screened with sera to determine antibody signatures indicative of the clinical stages of schistosomiasis and the identification of subunit vaccine candidates. Herein, we describe the methods used to derive the gene list for this array (representing approximately 10% of the predicted S. mansoni proteome). We also probed a pilot version of the microarray with sera from individuals either acutely or chronically infected with S. mansoni from endemic areas in Brazil and sera from individuals resident outside the endemic area (USA) to determine if the array is functional and informative.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15989/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Assis_Rafael_A next-generation_CPqRR_2016.pdfve_Assis_Rafael_A next-generation_CPqRR_2016.pdfapplication/pdf1244648https://www.arca.fiocruz.br/bitstream/icict/15989/2/ve_Assis_Rafael_A%20next-generation_CPqRR_2016.pdfb5bcd620b5bcd141ae4239cab8aad9f7MD52TEXTve_Assis_Rafael_A next-generation_CPqRR_2016.pdf.txtve_Assis_Rafael_A next-generation_CPqRR_2016.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv A next-generation proteome array for Schistosoma mansoni
title A next-generation proteome array for Schistosoma mansoni
spellingShingle A next-generation proteome array for Schistosoma mansoni
Assis, Rafael Ramiro de
anticorpos
proteomes
Antibody signature
Protein microarray
Proteome
Schistosoma mansoni
title_short A next-generation proteome array for Schistosoma mansoni
title_full A next-generation proteome array for Schistosoma mansoni
title_fullStr A next-generation proteome array for Schistosoma mansoni
title_full_unstemmed A next-generation proteome array for Schistosoma mansoni
title_sort A next-generation proteome array for Schistosoma mansoni
author Assis, Rafael Ramiro de
author_facet Assis, Rafael Ramiro de
Ludolf, Fernanda
Nakajima, Rie
Jasinskas, Al
Oliveira, Guilherme Correa de
Felgner, Philip L.
Jangola, Soraya Torres Gaze
Loukas, Alex
LoVerde, Philip T.
Bethony, Jeffrey Michael
Oliveira, Rodrigo Correa de
Silva, Carlos Eduardo Calzavara
author_role author
author2 Ludolf, Fernanda
Nakajima, Rie
Jasinskas, Al
Oliveira, Guilherme Correa de
Felgner, Philip L.
Jangola, Soraya Torres Gaze
Loukas, Alex
LoVerde, Philip T.
Bethony, Jeffrey Michael
Oliveira, Rodrigo Correa de
Silva, Carlos Eduardo Calzavara
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Assis, Rafael Ramiro de
Ludolf, Fernanda
Nakajima, Rie
Jasinskas, Al
Oliveira, Guilherme Correa de
Felgner, Philip L.
Jangola, Soraya Torres Gaze
Loukas, Alex
LoVerde, Philip T.
Bethony, Jeffrey Michael
Oliveira, Rodrigo Correa de
Silva, Carlos Eduardo Calzavara
dc.subject.other.pt_BR.fl_str_mv anticorpos
proteomes
topic anticorpos
proteomes
Antibody signature
Protein microarray
Proteome
Schistosoma mansoni
dc.subject.en.pt_BR.fl_str_mv Antibody signature
Protein microarray
Proteome
Schistosoma mansoni
description 2021-01-01
publishDate 2016
dc.date.accessioned.fl_str_mv 2016-09-28T17:58:58Z
dc.date.available.fl_str_mv 2016-09-28T17:58:58Z
dc.date.issued.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ASSIS, Rafael Ramiro de Assis, et al. A next-generation proteome array for Schistosoma mansoni. Int J Parasitol., v. 46, n. 7, p. 411-5, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15989
dc.identifier.issn.pt_BR.fl_str_mv 0020-7519
dc.identifier.doi.none.fl_str_mv 10.1016/j.ijpara.2016.04.001
identifier_str_mv ASSIS, Rafael Ramiro de Assis, et al. A next-generation proteome array for Schistosoma mansoni. Int J Parasitol., v. 46, n. 7, p. 411-5, 2016.
0020-7519
10.1016/j.ijpara.2016.04.001
url https://www.arca.fiocruz.br/handle/icict/15989
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Ltd.
publisher.none.fl_str_mv Elsevier Ltd.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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