From Type-1 Diabetes HPA Axis to the Disease Complications

Detalhes bibliográficos
Autor(a) principal: Torres, Rafael C.
Data de Publicação: 2013
Outros Autores: Prevatto, Jessika P., Silva, Patrícia M. R., Martinsand, Marco A., Carvalho, Vinicius F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/11743
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.
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spelling Torres, Rafael C.Prevatto, Jessika P.Silva, Patrícia M. R.Martinsand, Marco A.Carvalho, Vinicius F.2015-09-21T17:25:35Z2015-09-21T17:25:35Z2013TORRES, Rafael C.; et al. From Type-1 Diabetes HPA Axis to the Disease Complications. J Diabetes Metab., S12, 8p, 2013.1262-36362155-6156https://www.arca.fiocruz.br/handle/icict/1174310.4172/2155-6156.S12-002engOMICS InternationalFrom Type-1 Diabetes HPA Axis to the Disease Complicationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.Diabetes is a chronic metabolic disease whose incidence is increasing over the years in both developed and developing countries. Uncontrolled or poor controlled diabetic patients present several secondary complications induced by hyperglycemia, which are involved with the high morbidity and mortality of this disease. Moreover, the reduction of insulin production in diabetic patients induces increase of the activity of HPA axis that results in an increase of glucocorticoid production. This review gives an update of the state-of-the-art concerning the relationship of hyperactivity of HPA axis observed in type 1diabetic patients and the development of the disease complications.DiabetesGlucocorticoidGlucose metabolismHormonesHPA axisInsulinDiabetesGlucocorticoidesGlucoseDiabetes Mellitus Tipo 1InsulinaHormôniosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/11743/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALrafael_torres_etal_IOC_2013.pdfapplication/pdf5581398https://www.arca.fiocruz.br/bitstream/icict/11743/2/rafael_torres_etal_IOC_2013.pdf784af27cf1322486d2864e84ea4c9ed4MD52TEXTrafael_torres_etal_IOC_2013.pdf.txtrafael_torres_etal_IOC_2013.pdf.txtExtracted texttext/plain52571https://www.arca.fiocruz.br/bitstream/icict/11743/3/rafael_torres_etal_IOC_2013.pdf.txtc0a5cff470ba78b658600411910ebf37MD53icict/117432022-06-24 13:12:32.643oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T16:12:32Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv From Type-1 Diabetes HPA Axis to the Disease Complications
title From Type-1 Diabetes HPA Axis to the Disease Complications
spellingShingle From Type-1 Diabetes HPA Axis to the Disease Complications
Torres, Rafael C.
Diabetes
Glucocorticoid
Glucose metabolism
Hormones
HPA axis
Insulin
Diabetes
Glucocorticoides
Glucose
Diabetes Mellitus Tipo 1
Insulina
Hormônios
title_short From Type-1 Diabetes HPA Axis to the Disease Complications
title_full From Type-1 Diabetes HPA Axis to the Disease Complications
title_fullStr From Type-1 Diabetes HPA Axis to the Disease Complications
title_full_unstemmed From Type-1 Diabetes HPA Axis to the Disease Complications
title_sort From Type-1 Diabetes HPA Axis to the Disease Complications
author Torres, Rafael C.
author_facet Torres, Rafael C.
Prevatto, Jessika P.
Silva, Patrícia M. R.
Martinsand, Marco A.
Carvalho, Vinicius F.
author_role author
author2 Prevatto, Jessika P.
Silva, Patrícia M. R.
Martinsand, Marco A.
Carvalho, Vinicius F.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Torres, Rafael C.
Prevatto, Jessika P.
Silva, Patrícia M. R.
Martinsand, Marco A.
Carvalho, Vinicius F.
dc.subject.en.pt_BR.fl_str_mv Diabetes
Glucocorticoid
Glucose metabolism
Hormones
HPA axis
Insulin
topic Diabetes
Glucocorticoid
Glucose metabolism
Hormones
HPA axis
Insulin
Diabetes
Glucocorticoides
Glucose
Diabetes Mellitus Tipo 1
Insulina
Hormônios
dc.subject.decs.pt_BR.fl_str_mv Diabetes
Glucocorticoides
Glucose
Diabetes Mellitus Tipo 1
Insulina
Hormônios
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Inflamação. Rio de Janeiro, RJ, Brasil.
publishDate 2013
dc.date.issued.fl_str_mv 2013
dc.date.accessioned.fl_str_mv 2015-09-21T17:25:35Z
dc.date.available.fl_str_mv 2015-09-21T17:25:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TORRES, Rafael C.; et al. From Type-1 Diabetes HPA Axis to the Disease Complications. J Diabetes Metab., S12, 8p, 2013.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/11743
dc.identifier.issn.pt_BR.fl_str_mv 1262-3636
2155-6156
dc.identifier.doi.pt_BR.fl_str_mv 10.4172/2155-6156.S12-002
identifier_str_mv TORRES, Rafael C.; et al. From Type-1 Diabetes HPA Axis to the Disease Complications. J Diabetes Metab., S12, 8p, 2013.
1262-3636
2155-6156
10.4172/2155-6156.S12-002
url https://www.arca.fiocruz.br/handle/icict/11743
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv OMICS International
publisher.none.fl_str_mv OMICS International
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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