Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2008 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/32538 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ. Brasil. |
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Fernandes, AlexandreIñiguez, Alena M.Lima, Valdirene S.Souza, Sheila M. F. Mendonça deFerreira, Luiz FernandoVicente, Ana Carolina P.Jansen, Ana Maria2019-04-16T18:01:17Z2019-04-16T18:01:17Z2008FERNANDES, Alexandre et al. Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil. Memórias do Instituto Oswaldo Cruz, v. 103, n. 5, p. 514-516, Aug. 2008.0074-0276https://www.arca.fiocruz.br/handle/icict/3253810.1590/S0074-027620080005000211678-8060engFundação Oswaldo Cruz. Instituto Oswaldo CruzTrypanosoma cruzi IDoença de ChagasMúmias brasileirasDNA AntigoMegacoloMinas GeraisBrazilian mummyChagas diseaseAncient DNATrypanosoma cruziMegacolonMegacoloPre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ. Brasil / Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Departamento de Endemias Samuel Pessoa. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Paleoparasitologia. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ. Brasil.We evaluated the presence and distribution of Trypanosoma cruzi DNA in a mummy presenting with megacolon that was dated as approximately 560 ± 40 years old. The mummy was from the Peruaçu Valley in the state of Minas Gerais, Brazil. All samples were positive for T. cruzi minicircle DNA, demonstrating the presence and broad dissemination of the parasite in this body. From one sample, a mini-exon gene fragment was recovered and characterized by sequencing and was found to belong to the T. cruzi I genotype. This finding suggests that T. cruzi I infected humans during the pre-Columbian times and that, in addition to T. cruzi infection, Chagas disease in Brazil most likely preceded European colonization.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/32538/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAlexandreFernandez_AlenaIniguez_etal_IOC_2008.pdfAlexandreFernandez_AlenaIniguez_etal_IOC_2008.pdfapplication/pdf360096https://www.arca.fiocruz.br/bitstream/icict/32538/2/AlexandreFernandez_AlenaIniguez_etal_IOC_2008.pdf0e7b0df50dfa27bff29c48998a492ceeMD52TEXTAlexandreFernandez_AlenaIniguez_etal_IOC_2008.pdf.txtAlexandreFernandez_AlenaIniguez_etal_IOC_2008.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| title |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| spellingShingle |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil Fernandes, Alexandre Trypanosoma cruzi I Doença de Chagas Múmias brasileiras DNA Antigo Megacolo Minas Gerais Brazilian mummy Chagas disease Ancient DNA Trypanosoma cruzi Megacolon Megacolo |
| title_short |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| title_full |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| title_fullStr |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| title_full_unstemmed |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| title_sort |
Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil |
| author |
Fernandes, Alexandre |
| author_facet |
Fernandes, Alexandre Iñiguez, Alena M. Lima, Valdirene S. Souza, Sheila M. F. Mendonça de Ferreira, Luiz Fernando Vicente, Ana Carolina P. Jansen, Ana Maria |
| author_role |
author |
| author2 |
Iñiguez, Alena M. Lima, Valdirene S. Souza, Sheila M. F. Mendonça de Ferreira, Luiz Fernando Vicente, Ana Carolina P. Jansen, Ana Maria |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Fernandes, Alexandre Iñiguez, Alena M. Lima, Valdirene S. Souza, Sheila M. F. Mendonça de Ferreira, Luiz Fernando Vicente, Ana Carolina P. Jansen, Ana Maria |
| dc.subject.other.pt_BR.fl_str_mv |
Trypanosoma cruzi I Doença de Chagas Múmias brasileiras DNA Antigo Megacolo Minas Gerais |
| topic |
Trypanosoma cruzi I Doença de Chagas Múmias brasileiras DNA Antigo Megacolo Minas Gerais Brazilian mummy Chagas disease Ancient DNA Trypanosoma cruzi Megacolon Megacolo |
| dc.subject.en.pt_BR.fl_str_mv |
Brazilian mummy Chagas disease Ancient DNA Trypanosoma cruzi Megacolon |
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Megacolo |
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Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Genética Molecular de Microorganismos. Rio de Janeiro, RJ. Brasil. |
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2008 |
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2008 |
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2019-04-16T18:01:17Z |
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2019-04-16T18:01:17Z |
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FERNANDES, Alexandre et al. Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil. Memórias do Instituto Oswaldo Cruz, v. 103, n. 5, p. 514-516, Aug. 2008. |
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https://www.arca.fiocruz.br/handle/icict/32538 |
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0074-0276 |
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10.1590/S0074-02762008000500021 |
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1678-8060 |
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FERNANDES, Alexandre et al. Pre-Columbian Chagas disease in Brazil: Trypanosoma cruzi I in the archaeological remains of a human in Peruaçu Valley, Minas Gerais, Brazil. Memórias do Instituto Oswaldo Cruz, v. 103, n. 5, p. 514-516, Aug. 2008. 0074-0276 10.1590/S0074-02762008000500021 1678-8060 |
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