Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired.
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1371/journal.pntd.0002572 |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/7487 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Bahiana School of Medicine and Public Health. Salvador, BA, Brasil |
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Barbosa, Lúcio MacedoSilva, Luciano KalabricReis, Eliana Almeida GomesCarmo, Theomira Mauadie de AzevedoBlank, Walter AReis, Mitermayer Galvão dosBlanton, Ronald EdwardCosta, Jackson Mauricio Lopes2014-04-02T18:05:39Z2014-04-02T18:05:39Z2013BARBOSA, L. M. et al. Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. PLoS Neglected Tropical Disease, v. 7, n. 12, p. e2572, 2013.1935-2735https://www.arca.fiocruz.br/handle/icict/748710.1371/journal.pntd.0002572engPublic Library of ScienceEsquistossomoseSchistosoma mansoniInfecções parasitáriasParasitasInterações hospedeiro parasitaCaracterísticasEpidemiologiaBrasilIdadeSexoCharacteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Bahiana School of Medicine and Public Health. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilCase Western Reserve University. Center for Global Health and Diseases. Cleveland, Ohio, USAFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilCase Western Reserve University. Center for Global Health and Diseases. Cleveland, Ohio, USA / Louis Stokes Cleveland VA Medical Centre. Infectious Diseases Service. Department of Veterans Affairs Medical Centre. Cleveland, Ohio, USABackground: Brazil remains the country in the Americas with the highest prevalence of schistosomiasis. A combination of control efforts and development, however, has sharply reduced its intensity and distribution. The acquisition of specific schistosome populations may be dependent on host characteristics such as sex, age, geography, work, habits and culture. How these and other host characteristics align with parasite subpopulations may guide approaches to improve control. Methodology: A cohort of more than 90% of the residents in two rural communities in Brazil participated in an epidemiologic survey of demographic, socio-economic and behavioral characteristics. The variables sex, age, intensity of infection, socio-economic index, % lifetime spent on site, previous infection, and trips outside the district were used to group parasites infecting individuals. Schistosoma mansoni infection status was determined by examination of stools submitted on 3 different days. The aggregate of eggs collected from the whole stool was used to determine degree of population differentiation from allele frequencies for 15 microsatellites. Conclusions/Significance: Infection prevalence was 41% for these communities, and the epidemiologic characteristics were similar to many of the endemic areas of Brazil and the world. Parasite population structuring was observed between the two communities (Jost’s D 0.046, CI95% 0.042–0.051), although separated by only 8 km and connected by a highway. No structuring was observed when infected individuals were stratified by host’s biologic, demographic or epidemiologic characteristics. Those most heavily infected best reflected the communities’ overall parasite diversity. The lack of differentiation within villages suggests that individuals are likely to get infected at the same sites or that the same parasite multilocus genotypes can be found at most sites. The geographic structuring between villages and the lack of structuring by age of the host further supports the impression of a population little affected by migration or drift.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALBarbosa LM Characteristics of the human....pdfBarbosa LM Characteristics of the human....pdfapplication/pdf402894https://www.arca.fiocruz.br/bitstream/icict/7487/1/Barbosa%20LM%20Characteristics%20of%20the%20human....pdf44b7af6b6572824e4ec714968988f992MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7487/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTBarbosa LM Characteristics of the human....pdf.txtBarbosa LM Characteristics of the human....pdf.txtExtracted texttext/plain53604https://www.arca.fiocruz.br/bitstream/icict/7487/5/Barbosa%20LM%20Characteristics%20of%20the%20human....pdf.txtd5a3fef21cf69d0a993fffb3f9a28697MD55THUMBNAILBarbosa LM Characteristics of the human....pdf.jpgBarbosa LM Characteristics of the human....pdf.jpgGenerated Thumbnailimage/jpeg2619https://www.arca.fiocruz.br/bitstream/icict/7487/4/Barbosa%20LM%20Characteristics%20of%20the%20human....pdf.jpg82136440baf77eb985600975a4346331MD54icict/74872023-03-15 14:33:12.215oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:12Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| title |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| spellingShingle |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. Barbosa, Lúcio Macedo Esquistossomose Schistosoma mansoni Infecções parasitárias Parasitas Interações hospedeiro parasita Características Epidemiologia Brasil Idade Sexo |
| title_short |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| title_full |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| title_fullStr |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| title_full_unstemmed |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| title_sort |
Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. |
| author |
Barbosa, Lúcio Macedo |
| author_facet |
Barbosa, Lúcio Macedo Silva, Luciano Kalabric Reis, Eliana Almeida Gomes Carmo, Theomira Mauadie de Azevedo Blank, Walter A Reis, Mitermayer Galvão dos Blanton, Ronald Edward Costa, Jackson Mauricio Lopes |
| author_role |
author |
| author2 |
Silva, Luciano Kalabric Reis, Eliana Almeida Gomes Carmo, Theomira Mauadie de Azevedo Blank, Walter A Reis, Mitermayer Galvão dos Blanton, Ronald Edward Costa, Jackson Mauricio Lopes |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Barbosa, Lúcio Macedo Silva, Luciano Kalabric Reis, Eliana Almeida Gomes Carmo, Theomira Mauadie de Azevedo Blank, Walter A Reis, Mitermayer Galvão dos Blanton, Ronald Edward Costa, Jackson Mauricio Lopes |
| dc.subject.other.pt_BR.fl_str_mv |
Esquistossomose Schistosoma mansoni Infecções parasitárias Parasitas Interações hospedeiro parasita Características Epidemiologia Brasil Idade Sexo |
| topic |
Esquistossomose Schistosoma mansoni Infecções parasitárias Parasitas Interações hospedeiro parasita Características Epidemiologia Brasil Idade Sexo |
| description |
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Bahiana School of Medicine and Public Health. Salvador, BA, Brasil |
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2013 |
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2013 |
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2014-04-02T18:05:39Z |
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2014-04-02T18:05:39Z |
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BARBOSA, L. M. et al. Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. PLoS Neglected Tropical Disease, v. 7, n. 12, p. e2572, 2013. |
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10.1371/journal.pntd.0002572 |
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BARBOSA, L. M. et al. Characteristics of the human host have little influence on which local Schistosoma mansoni populations are acquired. PLoS Neglected Tropical Disease, v. 7, n. 12, p. e2572, 2013. 1935-2735 10.1371/journal.pntd.0002572 |
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