Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country

Detalhes bibliográficos
Autor(a) principal: Silva, Ileia Ferreira da
Data de Publicação: 2019
Outros Autores: Silva, Ilce Ferreira da, Koifman, Rosalina Jorge
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42434
Resumo: Presented at the Toronto Global Cancer Control Conference, Toronto,Canada, March 1 to 3, 2018
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spelling Silva, Ileia Ferreira daSilva, Ilce Ferreira daKoifman, Rosalina Jorge2020-07-28T19:47:29Z2020-07-28T19:47:29Z2019Ferreira da Silva I, Ferreira da Silva I, Koifman RJ. Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country. J Glob Oncol. 2019;5:1-11. doi:10.1200/JGO.18.001992378-9506https://www.arca.fiocruz.br/handle/icict/4243410.1200/JGO.18.00199Presented at the Toronto Global Cancer Control Conference, Toronto,Canada, March 1 to 3, 2018Supported by the National Cancer Institute in Brazil and Oswaldo CruzFoundation, which have academic purposes only. Supported in part byCoordenação de Aperfeiçoamento de Pessoal de N ́ıvel Superior - Brasil(Finance Code 001).Fundação Oswaldo Cruz. Rio de Janeiro, RJ. Brasil./ Instituto Nacional de Câncer José Alencar Gomes da Silva. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira.Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira.Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Purpose: To estimate treatment delays and associated factors among women diagnosed with cervical cancer who were treated at the main cancer center in Rio de Janeiro, Brazil. Materials and methods: A retrospective cohort study was performed comprising 865 women newly diagnosed with cervical cancer between 2012 and 2014. Times from diagnosis to treatment initiation (less than or equal to 60 days) and from diagnosis to treatment ending (less than or equal to 120 days) were analyzed according to the Brazilian law for the treatment of patients with cancer. Associations between treatment delays and sociodemographic, economic, lifestyle, clinical, and treatment variables were estimated using logistic regression models, with 95% CIs. Results: The average age was 48 (± 13.7) years, and the median age was 47 years; 36.2% of patients had stage IIIB to IVA disease. The median time from diagnosis to treatment initiation was 114 days, which was statistically higher among women with stage IIB to IVA (105.5 days) compared with those with earlier stages (119 days). The delay in treatment initiation occurred in 92.8% of participants; the median time from diagnosis to treatment ending was 274 days, with a delay (more than 120 days) for 92.6% of patients. The median time interval from diagnosis to the first visit to the cancer center was 28 days, with a delay of more than 30 days for 46.6% of patients. Age (odds ratio [OR], 1.05; 95% CI,1.02 to 1.08), stage IIIB to IVA (OR, 0.38; 95% CI, 0.16 to 0.90), time to first visit to the cancer center (OR, 11.52; 95% CI, 4.32 to 30.66), chemoradiation treatment (OR, 4.56; 95% CI, 1.81 to 11.47), and adequate treatment (OR, 2.57; 95% CI, 1.26 to -5.40) were independently associated with delay of treatment initiation. Conclusion: Significant delays in treatment initiation and ending were observed in this studied population. The treatment initiation delay was positively associated with age, time interval more than 30 days from diagnosis to first specialist assessment at the cancer center, treatment with chemoradiation, and adequate treatment.engAmerican Society of Clinical Oncology [Society Publisher]Age FactorsBrazil / epidemiologyDeveloping CountriesDelayed DiagnosisCross-Sectional StudiesCohort StudiesChemoradiotherapyFemaleRetrospective StudiesMiddle AgedLife StyleHumansUterine Cervical Neoplasms / therapyTime-to-Treatment / statistics & numerical dataUterine Cervical Neoplasms / epidemiologyUterine Cervical Neoplasms / diagnosis Uterine Cervical Neoplasms / economicsCervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Countryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
title Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
spellingShingle Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
Silva, Ileia Ferreira da
Age Factors
Brazil / epidemiology
Developing Countries
Delayed Diagnosis
Cross-Sectional Studies
Cohort Studies
Chemoradiotherapy
Female
Retrospective Studies
Middle Aged
Life Style
Humans
Uterine Cervical Neoplasms / therapy
Time-to-Treatment / statistics & numerical data
Uterine Cervical Neoplasms / epidemiology
Uterine Cervical Neoplasms / diagnosis Uterine Cervical Neoplasms / economics
title_short Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
title_full Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
title_fullStr Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
title_full_unstemmed Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
title_sort Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country
author Silva, Ileia Ferreira da
author_facet Silva, Ileia Ferreira da
Silva, Ilce Ferreira da
Koifman, Rosalina Jorge
author_role author
author2 Silva, Ilce Ferreira da
Koifman, Rosalina Jorge
author2_role author
author
dc.contributor.author.fl_str_mv Silva, Ileia Ferreira da
Silva, Ilce Ferreira da
Koifman, Rosalina Jorge
dc.subject.mesh.pt_BR.fl_str_mv Age Factors
Brazil / epidemiology
Developing Countries
Delayed Diagnosis
Cross-Sectional Studies
Cohort Studies
Chemoradiotherapy
Female
Retrospective Studies
Middle Aged
Life Style
Humans
Uterine Cervical Neoplasms / therapy
Time-to-Treatment / statistics & numerical data
Uterine Cervical Neoplasms / epidemiology
Uterine Cervical Neoplasms / diagnosis Uterine Cervical Neoplasms / economics
topic Age Factors
Brazil / epidemiology
Developing Countries
Delayed Diagnosis
Cross-Sectional Studies
Cohort Studies
Chemoradiotherapy
Female
Retrospective Studies
Middle Aged
Life Style
Humans
Uterine Cervical Neoplasms / therapy
Time-to-Treatment / statistics & numerical data
Uterine Cervical Neoplasms / epidemiology
Uterine Cervical Neoplasms / diagnosis Uterine Cervical Neoplasms / economics
description Presented at the Toronto Global Cancer Control Conference, Toronto,Canada, March 1 to 3, 2018
publishDate 2019
dc.date.issued.fl_str_mv 2019
dc.date.accessioned.fl_str_mv 2020-07-28T19:47:29Z
dc.date.available.fl_str_mv 2020-07-28T19:47:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Ferreira da Silva I, Ferreira da Silva I, Koifman RJ. Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country. J Glob Oncol. 2019;5:1-11. doi:10.1200/JGO.18.00199
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42434
dc.identifier.issn.pt_BR.fl_str_mv 2378-9506
dc.identifier.doi.none.fl_str_mv 10.1200/JGO.18.00199
identifier_str_mv Ferreira da Silva I, Ferreira da Silva I, Koifman RJ. Cervical Cancer Treatment Delays and Associated Factors in a Cohort of Women From a Developing Country. J Glob Oncol. 2019;5:1-11. doi:10.1200/JGO.18.00199
2378-9506
10.1200/JGO.18.00199
url https://www.arca.fiocruz.br/handle/icict/42434
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv American Society of Clinical Oncology [Society Publisher]
publisher.none.fl_str_mv American Society of Clinical Oncology [Society Publisher]
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/42434/1/license.txt
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