Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India

Detalhes bibliográficos
Autor(a) principal: Cornetta, Kenneth
Data de Publicação: 2022
Outros Autores: Bonamino, Martín, Mahlangu, Johnny, Mingozzi, Federico, Rangarajan, Savita, Rao, Jayandharan
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/57053
Resumo: Department of Medical and Molecular Genetics. Indiana University School of Medicine. Indianapolis, USA.
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spelling Cornetta, KennethBonamino, MartínMahlangu, JohnnyMingozzi, FedericoRangarajan, SavitaRao, Jayandharan2023-02-14T01:55:00Z2023-02-14T01:55:00Z2022CORNETTA, Kenneth et al. Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India. Molecular Therapy, v. 30, n. 6, p. 2122-2129, Jun. 2022.1525-0016https://www.arca.fiocruz.br/handle/icict/5705310.1016/j.ymthe.2022.04.0021525-0024engMedscapeGene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and Indiainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDepartment of Medical and Molecular Genetics. Indiana University School of Medicine. Indianapolis, USA.Molecular Carcinogenesis Program, Research, Coordination National Cancer Institute. Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. Presidency. Vice-Presidency Research and Biological Collections. Rio de Janeiro, RJ, Brazil.Department of Molecular Medicine and Haematology. School of Pathology. Faculty of Health Sciences. University of the Witwatersrand. Johannesburg, South Africa.Spark Therapeutics. Philadelphia, USA.Faculty of Medicine. University of Southampton. UK & KJ Somaiya. Super Speciality Hospital and Research Centre. Mumbai, India.Department of Biological Sciences and Bioengineering. Indian Institute of Technology Kanpur. Kapur, India.Gene and cell therapies for a variety of life-limiting illnesses are under investigation, and a small number of commercial products have successfully obtained regulatory approval. The cost of treatment is high, and clinical studies evaluating safety and efficacy are performed predominately in high-income countries. We reviewed the current status of gene and cell therapies in low- and middle-income countries and highlighted the need and current barriers to access. The state of product development in Brazil, South Africa, and India is discussed, including lessons learned from American Society of Gene and Cell Therapy (ASGCT)-sponsored virtual symposia in each of these countries.Gene therapy accessGlobal challengesCell therapiesCancer deathsGene therapy clinicalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALCornetta_Kenneth_etal_Presidência_2022.pdfCornetta_Kenneth_etal_Presidência_2022.pdfapplication/pdf422531https://www.arca.fiocruz.br/bitstream/icict/57053/2/Cornetta_Kenneth_etal_Presid%c3%aancia_2022.pdf97f2d08ab40c3fef04075459040b0e3bMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/57053/1/license.txt5a560609d32a3863062d77ff32785d58MD51icict/570532023-04-06 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dc.title.en_US.fl_str_mv Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
title Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
spellingShingle Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
Cornetta, Kenneth
Gene therapy access
Global challenges
Cell therapies
Cancer deaths
Gene therapy clinical
title_short Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
title_full Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
title_fullStr Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
title_full_unstemmed Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
title_sort Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India
author Cornetta, Kenneth
author_facet Cornetta, Kenneth
Bonamino, Martín
Mahlangu, Johnny
Mingozzi, Federico
Rangarajan, Savita
Rao, Jayandharan
author_role author
author2 Bonamino, Martín
Mahlangu, Johnny
Mingozzi, Federico
Rangarajan, Savita
Rao, Jayandharan
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cornetta, Kenneth
Bonamino, Martín
Mahlangu, Johnny
Mingozzi, Federico
Rangarajan, Savita
Rao, Jayandharan
dc.subject.en.none.fl_str_mv Gene therapy access
Global challenges
Cell therapies
Cancer deaths
Gene therapy clinical
topic Gene therapy access
Global challenges
Cell therapies
Cancer deaths
Gene therapy clinical
description Department of Medical and Molecular Genetics. Indiana University School of Medicine. Indianapolis, USA.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-02-14T01:55:00Z
dc.date.available.fl_str_mv 2023-02-14T01:55:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CORNETTA, Kenneth et al. Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India. Molecular Therapy, v. 30, n. 6, p. 2122-2129, Jun. 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/57053
dc.identifier.issn.en_US.fl_str_mv 1525-0016
dc.identifier.doi.none.fl_str_mv 10.1016/j.ymthe.2022.04.002
dc.identifier.eissn.none.fl_str_mv 1525-0024
identifier_str_mv CORNETTA, Kenneth et al. Gene therapy access: Global challenges, opportunities, and views from Brazil, South Africa, and India. Molecular Therapy, v. 30, n. 6, p. 2122-2129, Jun. 2022.
1525-0016
10.1016/j.ymthe.2022.04.002
1525-0024
url https://www.arca.fiocruz.br/handle/icict/57053
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Medscape
publisher.none.fl_str_mv Medscape
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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