Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/19473 |
Resumo: | Federal University of Pernambuco. Department of Genetics. Recife, PE, Brazil. |
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Silva, Lidiane Gomes daCosta Júnior, César Raimundo LimaFigueiredo Júnior, Carlos Alberto SantiagoLeal-Balbino, Tereza CristinaCrovella, SergioOtranto, DomenicoBalbino, Valdir de QueirozTorres, Filipe Dantas2017-06-21T17:22:26Z2017-06-21T17:22:26Z2017DA SILVA, L. G. et al. Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs. Parasites & Vectors, v. 10, n. 1, dez. 2017.1756-3305https://www.arca.fiocruz.br/handle/icict/1947310.1186/s13071-017-2130-8engGene β-defensina-1 caninaPolimorfismos de nucleotídeo únicoLeishmaniose caninaCãesCanine β-defensin-1 geneSingle nucleotide polymorphismsCanine leishmaniasisDogsDoenças do Cão / genéticaLeishmaniose Visceral / veterináriaReação em Cadeia da Polimerase em Tempo Realbeta-defensens / genéticaLeishmania infantum / isolamento & purificaçãoLeishmaniose Visceral / genéticaCanine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Pernambuco. Department of Genetics. Recife, PE, Brazil.Federal University of Pernambuco. Department of Genetics. Recife, PE, Brazil.Federal University of Pernambuco. Department of Genetics. Recife, PE, Brazil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Microbiologia. Recife, PE, Brasil.Federal University of Pernambuco. Department of Genetics. Recife, PE, Brazil.University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy.Federal University of Pernambuco. Department of Genetics. Recife, PE, Brazil.University of Bari. Department of Veterinary Medicine. Valenzano, Bari, Italy / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil.Canine leishmaniasis caused by Leishmania infantum is a parasitic disease of great veterinary significance. Some dogs infected by L. infantum may mount a strong cellular immune response and clear the infection, while others may respond with exaggerated antibody production against the parasite and develop an overt disease, which may be fatal, if left untreated. The initial factors triggering the polarization of the immune response towards a predominantly T-helper 1 or T-helper 2 cytokines, as well as the markers of resistance and susceptibility to L. infantum infection and disease development in dogs, are not fully understood. Herein, we assessed the association between single nucleotide polymorphisms (SNPs) in the canine β-defensin-1 (CBD1) gene and the infection by L. infantum in two dog populations from Brazil (Sobral in Ceará State and São Raimundo Nonato in Piauí State) and one dog population from Italy.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19473/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL28427438 2017 sil-can.pdf28427438 2017 sil-can.pdfapplication/pdf431023https://www.arca.fiocruz.br/bitstream/icict/19473/2/28427438%202017%20sil-can.pdfa3abdb879be58918eee34181399a196dMD52TEXT28427438 2017 sil-can.pdf.txt28427438 2017 sil-can.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| title |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| spellingShingle |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs Silva, Lidiane Gomes da Gene β-defensina-1 canina Polimorfismos de nucleotídeo único Leishmaniose canina Cães Canine β-defensin-1 gene Single nucleotide polymorphisms Canine leishmaniasis Dogs Doenças do Cão / genética Leishmaniose Visceral / veterinária Reação em Cadeia da Polimerase em Tempo Real beta-defensens / genética Leishmania infantum / isolamento & purificação Leishmaniose Visceral / genética |
| title_short |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| title_full |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| title_fullStr |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| title_full_unstemmed |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| title_sort |
Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs |
| author |
Silva, Lidiane Gomes da |
| author_facet |
Silva, Lidiane Gomes da Costa Júnior, César Raimundo Lima Figueiredo Júnior, Carlos Alberto Santiago Leal-Balbino, Tereza Cristina Crovella, Sergio Otranto, Domenico Balbino, Valdir de Queiroz Torres, Filipe Dantas |
| author_role |
author |
| author2 |
Costa Júnior, César Raimundo Lima Figueiredo Júnior, Carlos Alberto Santiago Leal-Balbino, Tereza Cristina Crovella, Sergio Otranto, Domenico Balbino, Valdir de Queiroz Torres, Filipe Dantas |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva, Lidiane Gomes da Costa Júnior, César Raimundo Lima Figueiredo Júnior, Carlos Alberto Santiago Leal-Balbino, Tereza Cristina Crovella, Sergio Otranto, Domenico Balbino, Valdir de Queiroz Torres, Filipe Dantas |
| dc.subject.other.none.fl_str_mv |
Gene β-defensina-1 canina Polimorfismos de nucleotídeo único Leishmaniose canina Cães |
| topic |
Gene β-defensina-1 canina Polimorfismos de nucleotídeo único Leishmaniose canina Cães Canine β-defensin-1 gene Single nucleotide polymorphisms Canine leishmaniasis Dogs Doenças do Cão / genética Leishmaniose Visceral / veterinária Reação em Cadeia da Polimerase em Tempo Real beta-defensens / genética Leishmania infantum / isolamento & purificação Leishmaniose Visceral / genética |
| dc.subject.en.none.fl_str_mv |
Canine β-defensin-1 gene Single nucleotide polymorphisms Canine leishmaniasis Dogs |
| dc.subject.decs.none.fl_str_mv |
Doenças do Cão / genética Leishmaniose Visceral / veterinária Reação em Cadeia da Polimerase em Tempo Real beta-defensens / genética Leishmania infantum / isolamento & purificação Leishmaniose Visceral / genética |
| description |
Federal University of Pernambuco. Department of Genetics. Recife, PE, Brazil. |
| publishDate |
2017 |
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2017-06-21T17:22:26Z |
| dc.date.available.fl_str_mv |
2017-06-21T17:22:26Z |
| dc.date.issued.fl_str_mv |
2017 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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DA SILVA, L. G. et al. Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs. Parasites & Vectors, v. 10, n. 1, dez. 2017. |
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https://www.arca.fiocruz.br/handle/icict/19473 |
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1756-3305 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1186/s13071-017-2130-8 |
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DA SILVA, L. G. et al. Canine β-defensin-1 (CBD1) gene as a possible marker for Leishmania infantum infection in dogs. Parasites & Vectors, v. 10, n. 1, dez. 2017. 1756-3305 10.1186/s13071-017-2130-8 |
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