Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/13862 |
Resumo: | 2017-11-30 |
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Basano, Sergio de AlmeidaFontes, GilbertoMedeiros, Jansen FernandesCamargo, Juliana Souza de Almeida AranhaVera, Luana Janaína SouzaAraújo, Marcos Paulo ParenteParente, Maira Santiago PiresFerreira, Ricardo de Godoi MattosCrispim, Pedro di Tárique BarretoCamargo, Luís Marcelo Aranha2016-04-19T14:17:14Z2014MEDEIROS, J. F. et al. Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon. The American Journal of Tropical Medicine and Hygiene. v. 90, p. 1170-1175, 2014.https://www.arca.fiocruz.br/handle/icict/1386210.4269/ajtmh.13-0410engAmerican Journal of Tropical Medicine and HygieneMansonella ozzardiInfectionIvermectinBrazilian AmazonSustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazoninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2017-11-30Secretaria de Saúde do Estado de Rondônia. Porto Velho, RO, Brazil. / Faculdade São Lucas. Departamento de Medicina. Porto Velho, RO, Brazil.Universidade Federal de São João Del Rei. Divinópolis, MG, Brazil.Fundação Oswaldo Cruz. Porto Velho, RO, Brazil.Fundação Oswaldo Cruz. Porto Velho, RO, Brazil.Faculdade São Lucas. Porto Velho, RO, Brazil.Faculdade São Lucas. Porto Velho, RO, Brazil.Faculdade São Lucas. Porto Velho, RO, Brazil.Faculdade São Lucas. Porto Velho, RO, Brazil.Universidade Federal de Rondônia. Porto Velho, RO, Brazil.Faculdade São Lucas. Departamento de Medicina. Porto Velho, RO, Brasil. / Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. São Paulo, SP, Brazil.Therapy for mansonelliasis is challenging because there is no standard drug recommended for its treatment. This non-randomized study was conducted to evaluate the effectiveness of a single dose of 0.15 mg/kg of ivermectin to reduce Mansonella ozzardi microfilaraemia in infected persons. A total of 74 patients were studied within the municipality of Lábrea, which is located in Amazonas State, Brazil. The patients were treated with ivermectin after detection of the parasite by blood examination. Significant microfilaraemia reduction was observed and its residual effect was maintained for at least 12 months. There was no significant change in the laboratory blood count, hepatic metabolites, and nitrogen-bounding compound excreta dosage values that could compromise the use of this drug, demonstrating that ivermectin has a low toxicity level.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13862/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSustained Clearance.pdfSustained Clearance.pdfapplication/pdf781069https://www.arca.fiocruz.br/bitstream/icict/13862/2/Sustained%20Clearance.pdfe3c4111b859b7b3bb4638646dd6fbdedMD52TEXTSustained Clearance.pdf.txtSustained Clearance.pdf.txtExtracted texttext/plain32723https://www.arca.fiocruz.br/bitstream/icict/13862/3/Sustained%20Clearance.pdf.txtdeedc2a60bc2d588437ccc3994162cd2MD53icict/138622021-02-10 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| dc.title.pt_BR.fl_str_mv |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| title |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| spellingShingle |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon Basano, Sergio de Almeida Mansonella ozzardi Infection Ivermectin Brazilian Amazon |
| title_short |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| title_full |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| title_fullStr |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| title_full_unstemmed |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| title_sort |
Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon |
| author |
Basano, Sergio de Almeida |
| author_facet |
Basano, Sergio de Almeida Fontes, Gilberto Medeiros, Jansen Fernandes Camargo, Juliana Souza de Almeida Aranha Vera, Luana Janaína Souza Araújo, Marcos Paulo Parente Parente, Maira Santiago Pires Ferreira, Ricardo de Godoi Mattos Crispim, Pedro di Tárique Barreto Camargo, Luís Marcelo Aranha |
| author_role |
author |
| author2 |
Fontes, Gilberto Medeiros, Jansen Fernandes Camargo, Juliana Souza de Almeida Aranha Vera, Luana Janaína Souza Araújo, Marcos Paulo Parente Parente, Maira Santiago Pires Ferreira, Ricardo de Godoi Mattos Crispim, Pedro di Tárique Barreto Camargo, Luís Marcelo Aranha |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Basano, Sergio de Almeida Fontes, Gilberto Medeiros, Jansen Fernandes Camargo, Juliana Souza de Almeida Aranha Vera, Luana Janaína Souza Araújo, Marcos Paulo Parente Parente, Maira Santiago Pires Ferreira, Ricardo de Godoi Mattos Crispim, Pedro di Tárique Barreto Camargo, Luís Marcelo Aranha |
| dc.subject.other.en.fl_str_mv |
Mansonella ozzardi Infection Ivermectin Brazilian Amazon |
| topic |
Mansonella ozzardi Infection Ivermectin Brazilian Amazon |
| description |
2017-11-30 |
| publishDate |
2014 |
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2014 |
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2016-04-19T14:17:14Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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MEDEIROS, J. F. et al. Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon. The American Journal of Tropical Medicine and Hygiene. v. 90, p. 1170-1175, 2014. |
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https://www.arca.fiocruz.br/handle/icict/13862 |
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10.4269/ajtmh.13-0410 |
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MEDEIROS, J. F. et al. Sustained Clearance of Mansonella ozzardi Infection after Treatment with Ivermectin in the Brazilian Amazon. The American Journal of Tropical Medicine and Hygiene. v. 90, p. 1170-1175, 2014. 10.4269/ajtmh.13-0410 |
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American Journal of Tropical Medicine and Hygiene |
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American Journal of Tropical Medicine and Hygiene |
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