Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital

Detalhes bibliográficos
Autor(a) principal: Lima, Catarina Tenório de
Data de Publicação: 2017
Outros Autores: Araújo, Paulo Sérgio Ramos de, Teixeira, Heberton Medeiros de, Santos, Josemir Belo Dos, Silveira, Vera Magalhães da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/19417
Resumo: Commission and Hospital Infection Control Service of the Hospital Barão de Lucena. Recife, PE, Brazil.
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spelling Lima, Catarina Tenório deAraújo, Paulo Sérgio Ramos deTeixeira, Heberton Medeiros deSantos, Josemir Belo DosSilveira, Vera Magalhães da2017-06-19T19:21:51Z2017-06-19T19:21:51Z2017LIMA, C. T. DE et al. Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi’s sarcoma at an university hospital. Anais Brasileiros de Dermatologia, v. 92, n. 2, p. 172–176, mar. 2017.1806-4841https://www.arca.fiocruz.br/handle/icict/1941710.1590/abd1806-4841.20175377engSíndrome da Imunodeficiência AdquiridaHIVNeoplasiasSarcoma, KaposiAcquired immunodeficiency syndromeHIVNeoplasmsSarcoma, KaposiInfecções Oportunistas Relacionadas com a AIDS / mortalidadeSarcoma , Kaposi / mortalidadeBrasil / epidemiologiaClinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospitalinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleCommission and Hospital Infection Control Service of the Hospital Barão de Lucena. Recife, PE, Brazil.Universidade Federal de Pernambuco. Department of Tropical Medicine. Recife, PE, Brazil / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Real Hospital Português de Beneficência de Pernambuco. Department of Clinical Oncology. Recife, PE, Brazil / Hospital Barão de Lucena. Department of Clinical Oncology. Recife, PE, Brazil.Universidade Federal de Pernambuco. Department of Tropical Medicine. Recife, PE, Brazil / Dermatology Service of the Hospital das Clínicas of the Universidade Federal de Pernambuco (HC-UFPE). Recife, PE, Brazil.Universidade Federal de Pernambuco. Department of Tropical Medicine. Recife, PE, Brazil.Background: Kaposi's sarcoma continues to be the most common human immunodeficiency virus - associated neoplasm with considerable morbidity and mortality. Objective: To describe the clinical and laboratory characteristics, initial staging, and outcomes of aids patients with Kaposi's sarcoma at an university hospital of Recife, Pernambuco. Methods: This is a descriptive study with analytic character, retrospective, of a case series between 2004 and 2014. Results: Of the 22 patients included in the study, 20 were aged <40 years (72.7%). The majority had CD4+ T lymphocyte counts of <200 cells/mm3 (77.3%) and human immunodeficiency virus loads of <100,000 copies/mL (78.9%). Lesions were most commonly observed on the skin (90%), and internal organs were affected in 11 of the 22 patients. Only 7 (31.8%) of the 22 patients were undergoing antiretroviral therapy (ART) at the time of Kaposis sarcoma diagnosis, and the initial disease staging classification was high risk (Aids Clinical Trials Group Oncology Committee) in 19 of the 22 patients (86.4%). Regarding Kaposi's sarcoma treatment, 17 of 22 patients (77.3%) underwent systemic chemotherapy + ART and 5 were treated exclusively with ART. Eight of the 22 patients died (36.5%); of these, 87.5% had died within one year of Kaposi's sarcoma diagnosis. Limitation of the study: Without a control group, this study cannot be used to generate hypotheses. Conclusions: Despite the association between aids and late Kaposi's sarcoma diagnosis in the study population, including an unfavorable risk at the time of staging, a lower mortality rate was observed relative to other studies; this might be related to access to a specialized health service.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19417/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL28538874 2017 lim-clin.oa.pdf28538874 2017 lim-clin.oa.pdfapplication/pdf287529https://www.arca.fiocruz.br/bitstream/icict/19417/2/28538874%202017%20lim-clin.oa.pdfc9afa11ebf83a86fc4e42c532ae83f6dMD52TEXT28538874 2017 lim-clin.oa.pdf.txt28538874 2017 lim-clin.oa.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
title Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
spellingShingle Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
Lima, Catarina Tenório de
Síndrome da Imunodeficiência Adquirida
HIV
Neoplasias
Sarcoma, Kaposi
Acquired immunodeficiency syndrome
HIV
Neoplasms
Sarcoma, Kaposi
Infecções Oportunistas Relacionadas com a AIDS / mortalidade
Sarcoma , Kaposi / mortalidade
Brasil / epidemiologia
title_short Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
title_full Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
title_fullStr Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
title_full_unstemmed Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
title_sort Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital
author Lima, Catarina Tenório de
author_facet Lima, Catarina Tenório de
Araújo, Paulo Sérgio Ramos de
Teixeira, Heberton Medeiros de
Santos, Josemir Belo Dos
Silveira, Vera Magalhães da
author_role author
author2 Araújo, Paulo Sérgio Ramos de
Teixeira, Heberton Medeiros de
Santos, Josemir Belo Dos
Silveira, Vera Magalhães da
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lima, Catarina Tenório de
Araújo, Paulo Sérgio Ramos de
Teixeira, Heberton Medeiros de
Santos, Josemir Belo Dos
Silveira, Vera Magalhães da
dc.subject.other.none.fl_str_mv Síndrome da Imunodeficiência Adquirida
HIV
Neoplasias
Sarcoma, Kaposi
topic Síndrome da Imunodeficiência Adquirida
HIV
Neoplasias
Sarcoma, Kaposi
Acquired immunodeficiency syndrome
HIV
Neoplasms
Sarcoma, Kaposi
Infecções Oportunistas Relacionadas com a AIDS / mortalidade
Sarcoma , Kaposi / mortalidade
Brasil / epidemiologia
dc.subject.en.none.fl_str_mv Acquired immunodeficiency syndrome
HIV
Neoplasms
Sarcoma, Kaposi
dc.subject.decs.none.fl_str_mv Infecções Oportunistas Relacionadas com a AIDS / mortalidade
Sarcoma , Kaposi / mortalidade
Brasil / epidemiologia
description Commission and Hospital Infection Control Service of the Hospital Barão de Lucena. Recife, PE, Brazil.
publishDate 2017
dc.date.accessioned.fl_str_mv 2017-06-19T19:21:51Z
dc.date.available.fl_str_mv 2017-06-19T19:21:51Z
dc.date.issued.fl_str_mv 2017
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LIMA, C. T. DE et al. Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi’s sarcoma at an university hospital. Anais Brasileiros de Dermatologia, v. 92, n. 2, p. 172–176, mar. 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/19417
dc.identifier.issn.pt_BR.fl_str_mv 1806-4841
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/abd1806-4841.20175377
identifier_str_mv LIMA, C. T. DE et al. Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi’s sarcoma at an university hospital. Anais Brasileiros de Dermatologia, v. 92, n. 2, p. 172–176, mar. 2017.
1806-4841
10.1590/abd1806-4841.20175377
url https://www.arca.fiocruz.br/handle/icict/19417
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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