Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)

Detalhes bibliográficos
Autor(a) principal: Guimarães, F. Nery
Data de Publicação: 1955
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/52981
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
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spelling Guimarães, F. Nery2022-05-30T11:35:07Z2022-05-30T11:35:07Z1955GUIMARÃES. F. Nery. Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 53, n. 1, p. 1 - 11, 1955.0074-0206https://www.arca.fiocruz.br/handle/icict/5298110.1590/S0074-027619550001000011678-8060porFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Foco de LeishmanioseLeishmaniose muco-cutâneaBaixada FluminenseRio de JaneiroEstudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.The paper reports a survey made in a focus of muco-cutaneous leishmaniasis in a locality of the lowlands of the State of Rio de Janeiro, Brazil (Baixada Fluminense). The existence of the disease as an endemic of the region was confirmed by the finding of 21 cases with typical scars and responding positively to Montenegro's intradermo-reaction with specific antigen and some of them dating back from 5 to 15 years. At the time of the survey, however, an epidemic outbreak was discovered, coincidig with a great felling of trees for the making of charcoal. Out of 306 persons examined (50% of the local population), 39 presented leishmaniotic lesions (12,7%). Both within the houses and outside, adults Phlebotomus intermedius were captured. From 12 houses, 136 specimens were captured (11,3 per house). Out of 23 dogs examined, one was found with a probable diagnosis of elishmaniasis. Fifteen cats were found negative, as well as 28 small wild mammals. From the 39 patients, 4 had mucous lesions (10,3%), 16 presented multiple lesions (41,0%), and 19 were female (48,7%). There was an absolute predominance of lesions on bare parts of the body. About one third of the cases were children of 10 years or less, confirming the intense domiciliary transmission. Some houses had 2 to 6 patients. On basis of informations furnished by the patients of by their relatives as to the time elapsed since the beginning of the infection, and admitting an incubation period of 2 months, it is possible to conclude that the great majority of infections probably occurred between July and December, coinciding with the great felling of trees already referred to. In 36 cases Montenegro's intradermo-reaction was made, with 2 doubtful and 34 positive results of variable intensity. Eighteen biopsies were made, the epidermis presenting hyperacanthosis, and frquently pseudoepitheliomatosis with corneous globules and micro-abscesses. The dermis showed two characteristic pictures: an infiltration with predominance of plasmocytes or a granulomatous lesion with epithelioid and giant cells. In general, granulomatosis occurred in older cases, isolated or associated to infiltration with plasmocytes. It seems that granulomatosis represents a hyperergic condition of the infected organism, as the patients who showed it had the disease for a longer time and reponded strongly to the intradermo-reaction. Leishmaniae were not numerous in sections. Three patients showed spontaneous cure. Twenty six patients were treated, 16 with tartar emetic, 4 with "fuadin" and 4 with both these drugs. Some of the patients treated with tartar showed toxic symptoms, although the results were as good as those obtained with "fuadin". Two patients with nasal mucous lesions were not cured, notwithstanding the use of both these drugs. Five years after this survey, muco-cutaneous leishmaniasis was absent from the region, probably as a consequence of several preiodical DDT house sprayings to combate malaria during the intervening years (NERY GHIMARÃES & BUSTAMANTE, 1953).info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/52981/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALFNery_Guimaraes_IOC_v53_n1_1955.pdfFNery_Guimaraes_IOC_v53_n1_1955.pdfapplication/pdf1136051https://www.arca.fiocruz.br/bitstream/icict/52981/2/FNery_Guimaraes_IOC_v53_n1_1955.pdfcac54c32e8d7671ca4ec2235609cf2bcMD52icict/529812023-09-05 10:11:34.107oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-05T13:11:34Repositório Institucional da FIOCRUZ (ARCA) - 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dc.title.pt_BR.fl_str_mv Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
title Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
spellingShingle Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
Guimarães, F. Nery
Foco de Leishmaniose
Leishmaniose muco-cutânea
Baixada Fluminense
Rio de Janeiro
title_short Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
title_full Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
title_fullStr Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
title_full_unstemmed Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
title_sort Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro)
author Guimarães, F. Nery
author_facet Guimarães, F. Nery
author_role author
dc.contributor.author.fl_str_mv Guimarães, F. Nery
dc.subject.other.pt_BR.fl_str_mv Foco de Leishmaniose
Leishmaniose muco-cutânea
Baixada Fluminense
Rio de Janeiro
topic Foco de Leishmaniose
Leishmaniose muco-cutânea
Baixada Fluminense
Rio de Janeiro
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.
publishDate 1955
dc.date.issued.fl_str_mv 1955
dc.date.accessioned.fl_str_mv 2022-05-30T11:35:07Z
dc.date.available.fl_str_mv 2022-05-30T11:35:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GUIMARÃES. F. Nery. Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 53, n. 1, p. 1 - 11, 1955.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/52981
dc.identifier.issn.pt_BR.fl_str_mv 0074-0206
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761955000100001
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv GUIMARÃES. F. Nery. Estudo de um foco de Leishmaniose muco-cutânea na Baixada Fluminense (Estado do Rio de Janeiro). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 53, n. 1, p. 1 - 11, 1955.
0074-0206
10.1590/S0074-02761955000100001
1678-8060
url https://www.arca.fiocruz.br/handle/icict/52981
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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