Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2014 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/10881 |
Resumo: | Fundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil. |
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Santos, Eliane Matos dosSá, Gloria Regina da Silva eSiqueira, Marilda Agudo Mendonça Teixeira deMartins, Reinaldo de MenezesCamacho, Luiz Antonio Bastosvon Doellinger, Vanessa dos ReisMaia, Maria de Lourdes de Sousa2015-06-17T12:05:25Z2015-06-17T12:05:25Z2014SANTOS, Eliane Matos dos; et al. Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program. Mem Inst Oswaldo Cruz, v.109, n.3, p.335-339, May 2014.1678-8060https://www.arca.fiocruz.br/handle/icict/1088110.1590/0074-0276130351engFundação Oswaldo CruzImmune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Programinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil.A non-controlled longitudinal study was conducted to evaluate the combined vaccine against measles, mumps and rubella (MMR) immunogenicity in 150 children vaccinated in the routine of three health units in the city of Rio de Janeiro, Brazil, 2008-2009, without other vaccines administered during the period from 30 days before to 30 days after vaccination. A previous study conducted in Brazil in 2007, in 1,769 children ranging from 12-15 months of age vaccinated against yellow fever and MMR simultaneously or at intervals of 30 days or more between doses, had shown low seroconversion for mumps regardless of the interval between administration of the two vaccines. The current study showed 89.5% (95% confidence interval: 83.3; 94.0) seroconversion rate for mumps. All children seroconverted for measles and rubella. After revaccination, high antibody titres and seroconversion rates were achieved against mumps. The results of this study and others suggest that two MMR doses confer optimal immunoresponses for all three antigens and the possible need for additional doses should be studied taking into account not only serological, but also epidemiological data, as there is no serological correlate of protection for mumps.MMR VaccineImmunogenicityMumpsCaxumbaVacina contra Sarampo-Caxumba-Rubéolainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1914https://www.arca.fiocruz.br/bitstream/icict/10881/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALmarilda_siqueira3etal_IOC_2014.pdfapplication/pdf252716https://www.arca.fiocruz.br/bitstream/icict/10881/2/marilda_siqueira3etal_IOC_2014.pdf34ab3e4046a381c110d0c539556a78c1MD52TEXTmarilda_siqueira3etal_IOC_2014.pdf.txtmarilda_siqueira3etal_IOC_2014.pdf.txtExtracted texttext/plain24123https://www.arca.fiocruz.br/bitstream/icict/10881/3/marilda_siqueira3etal_IOC_2014.pdf.txt51f6527072f279d141f868aec3f111a4MD53icict/108812022-06-24 13:10:50.523oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-06-24T16:10:50Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| title |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| spellingShingle |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program Santos, Eliane Matos dos MMR Vaccine Immunogenicity Mumps Caxumba Vacina contra Sarampo-Caxumba-Rubéola |
| title_short |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| title_full |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| title_fullStr |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| title_full_unstemmed |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| title_sort |
Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program |
| author |
Santos, Eliane Matos dos |
| author_facet |
Santos, Eliane Matos dos Sá, Gloria Regina da Silva e Siqueira, Marilda Agudo Mendonça Teixeira de Martins, Reinaldo de Menezes Camacho, Luiz Antonio Bastos von Doellinger, Vanessa dos Reis Maia, Maria de Lourdes de Sousa |
| author_role |
author |
| author2 |
Sá, Gloria Regina da Silva e Siqueira, Marilda Agudo Mendonça Teixeira de Martins, Reinaldo de Menezes Camacho, Luiz Antonio Bastos von Doellinger, Vanessa dos Reis Maia, Maria de Lourdes de Sousa |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Santos, Eliane Matos dos Sá, Gloria Regina da Silva e Siqueira, Marilda Agudo Mendonça Teixeira de Martins, Reinaldo de Menezes Camacho, Luiz Antonio Bastos von Doellinger, Vanessa dos Reis Maia, Maria de Lourdes de Sousa |
| dc.subject.en.pt_BR.fl_str_mv |
MMR Vaccine Immunogenicity Mumps |
| topic |
MMR Vaccine Immunogenicity Mumps Caxumba Vacina contra Sarampo-Caxumba-Rubéola |
| dc.subject.decs.pt_BR.fl_str_mv |
Caxumba Vacina contra Sarampo-Caxumba-Rubéola |
| description |
Fundação Oswaldo Cruz. Bio-Manguinhos. Unidade de Assessoria Clínica. Rio de Janeiro, RJ, Brasil. |
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2014 |
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2014 |
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2015-06-17T12:05:25Z |
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2015-06-17T12:05:25Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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SANTOS, Eliane Matos dos; et al. Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program. Mem Inst Oswaldo Cruz, v.109, n.3, p.335-339, May 2014. |
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https://www.arca.fiocruz.br/handle/icict/10881 |
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1678-8060 |
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10.1590/0074-0276130351 |
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SANTOS, Eliane Matos dos; et al. Immune response to the mumps component of the MMR vaccine in the routine of immunisation services in the Brazilian National Immunisation Program. Mem Inst Oswaldo Cruz, v.109, n.3, p.335-339, May 2014. 1678-8060 10.1590/0074-0276130351 |
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