Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016

Barreira, Débora Maria Pires Gonçalves; Fumian, Túlio Machado; Tonini, Marco André Loureiro; Volpini, Lays Paula Bondi; Santos, Rodrigo Pratte; Ribeiro, Anézia Lima Chaves; Leite, José Paulo Gagliardi; Souza, Márcia Terezinha Baroni de Moraes e; Brasil, Patrícia; Cunha, Denise Cotrim da; Miagostovich, Marize Pereira; Spano, Liliana Cruz

Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016

Detalhes bibliográficos
Autor(a) principal:	Barreira, Débora Maria Pires Gonçalves
Data de Publicação:	2017
Outros Autores:	Fumian, Túlio Machado, Tonini, Marco André Loureiro, Volpini, Lays Paula Bondi, Santos, Rodrigo Pratte, Ribeiro, Anézia Lima Chaves, Leite, José Paulo Gagliardi, Souza, Márcia Terezinha Baroni de Moraes e, Brasil, Patrícia, Cunha, Denise Cotrim da, Miagostovich, Marize Pereira, Spano, Liliana Cruz
Tipo de documento:	Artigo
Idioma:	eng
Título da fonte:	Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo:	https://www.arca.fiocruz.br/handle/icict/34675
Resumo:	Federal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.

Metadados do item

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spelling	Barreira, Débora Maria Pires GonçalvesFumian, Túlio MachadoTonini, Marco André LoureiroVolpini, Lays Paula BondiSantos, Rodrigo PratteRibeiro, Anézia Lima ChavesLeite, José Paulo GagliardiSouza, Márcia Terezinha Baroni de Moraes eBrasil, PatríciaCunha, Denise Cotrim daMiagostovich, Marize PereiraSpano, Liliana Cruz2019-08-08T15:08:47Z2019-08-08T15:08:47Z2017BARREIRA, Débora Maria Pires Gonçalves et al. Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016. Plos One, p. 1-9, Dec. 2017.1932-6203https://www.arca.fiocruz.br/handle/icict/3467510.1371/journal.pone.01895041932-6203engPublic Library of ScienceDetection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Federal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.Federal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.Federal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.Central Laboratory of Public Health. Vitória, ES, Brazil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Doenças Febris Agudas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sérgio Arouca. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Comparada e Ambiental. Rio de Janeiro, RJ, Brasil.Federal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.Noroviruses are the leading cause of acute gastroenteritis (AGE) in all age groups worldwide. Despite the high genetic diversity of noroviruses, most AGE outbreaks are caused by a single norovirus genotype: GII.4. Since 1995, several different variants of norovirus GII.4 have been associated with pandemics, with each variant circulating for 3 to 8 years. The Sydney_2012 variant was first reported in Australia and then in other countries. A new variant, GII.P16-GII.4, was recently described in Japan and South Korea and then in the USA, France, Germany and England. In our study, 190 faecal specimens were collected from children admitted to a paediatric hospital and a public health facility during a surveillance study of sporadic cases of AGE conducted between January 2015 and July 2016. The norovirus was detected by RT-qPCR in 51 samples (26.8%), and in 37 of them (72.5%), the ORF1-2 junction was successfully sequenced. The new recombinant GII.P16-GII.4 Sydney was revealed for the first time in Brazil in 2016 and predominated among other strains (9 GII.Pe-GII.4, 3 GII.P17-GII.17, 1 GII.Pg-GII.1, 1 GII.P16-GII.3 and 1 GII.PNA-GII.4). The epidemiological significance of this new recombinant is still unknown, but continuous surveillance studies may evaluate its impact on the population, its potential to replace the first recombinant GII.Pe-GII.4 Sydney 2012 variant, and the emergence of new recombinant forms of GII.P16.Norovirus GII.P16-GII.4 SydneySoutheastern BrazilBrazilNorovirusesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/34675/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Barreira_Débora_etal_INI_2017.pdfve_Barreira_Débora_etal_INI_2017.pdfapplication/pdf4321989https://www.arca.fiocruz.br/bitstream/icict/34675/2/ve_Barreira_D%c3%a9bora_etal_INI_2017.pdfe9dcb6968a4161fd2eff30b73b4de183MD52TEXTve_Barreira_Débora_etal_INI_2017.pdf.txtve_Barreira_Débora_etal_INI_2017.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
title	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
spellingShingle	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016 Barreira, Débora Maria Pires Gonçalves Norovirus GII.P16-GII.4 Sydney Southeastern Brazil Brazil Noroviruses
title_short	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
title_full	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
title_fullStr	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
title_full_unstemmed	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
title_sort	Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016
author	Barreira, Débora Maria Pires Gonçalves
author_facet	Barreira, Débora Maria Pires Gonçalves Fumian, Túlio Machado Tonini, Marco André Loureiro Volpini, Lays Paula Bondi Santos, Rodrigo Pratte Ribeiro, Anézia Lima Chaves Leite, José Paulo Gagliardi Souza, Márcia Terezinha Baroni de Moraes e Brasil, Patrícia Cunha, Denise Cotrim da Miagostovich, Marize Pereira Spano, Liliana Cruz
author_role	author
author2	Fumian, Túlio Machado Tonini, Marco André Loureiro Volpini, Lays Paula Bondi Santos, Rodrigo Pratte Ribeiro, Anézia Lima Chaves Leite, José Paulo Gagliardi Souza, Márcia Terezinha Baroni de Moraes e Brasil, Patrícia Cunha, Denise Cotrim da Miagostovich, Marize Pereira Spano, Liliana Cruz
author2_role	author author author author author author author author author author author
dc.contributor.author.fl_str_mv	Barreira, Débora Maria Pires Gonçalves Fumian, Túlio Machado Tonini, Marco André Loureiro Volpini, Lays Paula Bondi Santos, Rodrigo Pratte Ribeiro, Anézia Lima Chaves Leite, José Paulo Gagliardi Souza, Márcia Terezinha Baroni de Moraes e Brasil, Patrícia Cunha, Denise Cotrim da Miagostovich, Marize Pereira Spano, Liliana Cruz
dc.subject.en.pt_BR.fl_str_mv	Norovirus GII.P16-GII.4 Sydney Southeastern Brazil Brazil Noroviruses
topic	Norovirus GII.P16-GII.4 Sydney Southeastern Brazil Brazil Noroviruses
description	Federal University of Espírito Santo. Health Science Center. Pathology Department. Laboratory of Virology and Infectious Gastroenteritis. Vitória, ES, Brazil.
publishDate	2017
dc.date.issued.fl_str_mv	2017
dc.date.accessioned.fl_str_mv	2019-08-08T15:08:47Z
dc.date.available.fl_str_mv	2019-08-08T15:08:47Z
dc.type.status.fl_str_mv	info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv	info:eu-repo/semantics/article
format	article
status_str	publishedVersion
dc.identifier.citation.fl_str_mv	BARREIRA, Débora Maria Pires Gonçalves et al. Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016. Plos One, p. 1-9, Dec. 2017.
dc.identifier.uri.fl_str_mv	https://www.arca.fiocruz.br/handle/icict/34675
dc.identifier.issn.pt_BR.fl_str_mv	1932-6203
dc.identifier.doi.none.fl_str_mv	10.1371/journal.pone.0189504
dc.identifier.eissn.none.fl_str_mv	1932-6203
identifier_str_mv	BARREIRA, Débora Maria Pires Gonçalves et al. Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016. Plos One, p. 1-9, Dec. 2017. 1932-6203 10.1371/journal.pone.0189504
url	https://www.arca.fiocruz.br/handle/icict/34675
dc.language.iso.fl_str_mv	eng
language	eng
dc.rights.driver.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	Public Library of Science
publisher.none.fl_str_mv	Public Library of Science
dc.source.none.fl_str_mv	reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ
instname_str	Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str	FIOCRUZ
institution	FIOCRUZ
reponame_str	Repositório Institucional da FIOCRUZ (ARCA)
collection	Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv	https://www.arca.fiocruz.br/bitstream/icict/34675/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/34675/2/ve_Barreira_D%c3%a9bora_etal_INI_2017.pdf https://www.arca.fiocruz.br/bitstream/icict/34675/3/ve_Barreira_D%c3%a9bora_etal_INI_2017.pdf.txt
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repository.name.fl_str_mv	Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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Detection and molecular characterization of the novel recombinant norovirus GII.P16-GII.4 Sydney in southeastern Brazil in 2016

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