Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil.
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/8496 |
Resumo: | Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil |
| id |
CRUZ_927bda57f84d3aef0f1f4ad8721e686b |
|---|---|
| oai_identifier_str |
oai:www.arca.fiocruz.br:icict/8496 |
| network_acronym_str |
CRUZ |
| network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| repository_id_str |
2135 |
| spelling |
Oliveira, Paula MatosMascarenhas, Rita Elizabeth MoreiraLacroix, ClaireFerrer, Suzana RamosOliveira, Rone Peterson CerqueiraCravo, Elaine AndradeAlves, André Pinheiro RibeiroGrassi, Maria Fernanda Rios2014-10-03T17:34:45Z2014-10-03T17:34:45Z2011OLIVEIRA, P. M. et al. Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. Brazilian Journal of Infectious Diseases, v. 15, n. 3, p. 239-244, 2011.1678-4391https://www.arca.fiocruz.br/handle/icict/8496engElsevier Editora LtdaCandida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleEscola Bahiana de Medicina e Saúde Pública. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, Ba, BrasilLaboratoire de Mycologie-Parasitologie. Paris, FranceEscola Bahiana de Medicina e Saúde Pública. Salvador, Ba, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, Ba, BrasilEscola Bahiana de Medicina e Saúde Pública. Salvador, Ba, BrasilFundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Laboratório Avançadao de Saúde Pública. Salvador, BA, BrasilBackground: Vulvovaginal candidiasis (VVC) is the second most common vaginal infection. HIV-infection is a risk factor for this infection. Objective: To determine the frequency of VVC and to describe the main Candida species isolated and their susceptibility to antifungal drugs in HIV-infected patients, compared to HIV-uninfected women in Salvador, Brazil. Methods: Cross-sectional study including a group of 64 HIV-infected women and 76 uninfected women, followed up at the AIDS reference center and at the Gynecological Clinic of Escola Bahiana de Medicina e Saúde Pública (Salvador, Bahia, Brazil). Results: Frequency of Candida spp. was higher in HIV-infected women (29.7%) than in HIV-uninfected controls (14.5%) (p = 0.02). The odds ratio value for vulvovaginal candidiasis in HIV-infected patients was 2.6 (95% CI: 1.07 - 6.32 p = 0.03). Candida albicans was the most commonly isolated species in both HIV-infected (52.3%) and uninfected women (85.7%), followed by C. parapsolis in 17.6% and 14.3%, respectively. In HIV-infected women, C. glabrata, C. parapsilosis, and a coinfection of C. albicans and C. glabrata were also identified. There was no significant difference between Candida species isolated from the vaginal mucosa of women with VVC and colonization of the vaginal mucosa of HIV-infected and HIV-uninfected women. One C. glabrata isolate from an HIV-infected patient was resistant to fluconazole and other two isolates exhibited a dose-dependent susceptibility. Conclusion: Our results confirm a higher frequency of Candida spp. isolated from the vaginal mucosa of HIV-infected women and a broader spectrum of species involved. Only Candida glabrata isolates showed decreased susceptibility to fluconazole.HIVCandidaCandidiasisVulvovaginalInfecções Oportunistas Relacionadas com a AIDS/microbiologiaCandida/isolamento & purificaçãoCandidíase Vulvovaginal/microbiologiaInfecções Oportunistas Relacionadas com a AIDS/diagnósticoAdultoAntifúngicos/farmacologiaBrasilCandida/classificaçãoCandida/efeitos de drogasCandidíase Vulvovaginal/diagnósticoFemininoHumanosTestes de Sensibilidade MicrobianaMembrana Mucosa/microbiologiaPrevalênciaVagina/microbiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8496/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALOliveira PM Candida species....pdfOliveira PM Candida species....pdfapplication/pdf872401https://www.arca.fiocruz.br/bitstream/icict/8496/2/Oliveira%20PM%20Candida%20species....pdf2ecc5beb865c4485a2faea6effe9c4aeMD52TEXTOliveira PM Candida species....pdf.txtOliveira PM Candida species....pdf.txtExtracted texttext/plain22735https://www.arca.fiocruz.br/bitstream/icict/8496/3/Oliveira%20PM%20Candida%20species....pdf.txtf909f405622e2fcf8fe654f6fb08fdb7MD53icict/84962023-03-15 14:33:56.255oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:56Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| title |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| spellingShingle |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. Oliveira, Paula Matos HIV Candida Candidiasis Vulvovaginal Infecções Oportunistas Relacionadas com a AIDS/microbiologia Candida/isolamento & purificação Candidíase Vulvovaginal/microbiologia Infecções Oportunistas Relacionadas com a AIDS/diagnóstico Adulto Antifúngicos/farmacologia Brasil Candida/classificação Candida/efeitos de drogas Candidíase Vulvovaginal/diagnóstico Feminino Humanos Testes de Sensibilidade Microbiana Membrana Mucosa/microbiologia Prevalência Vagina/microbiologia |
| title_short |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| title_full |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| title_fullStr |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| title_full_unstemmed |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| title_sort |
Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. |
| author |
Oliveira, Paula Matos |
| author_facet |
Oliveira, Paula Matos Mascarenhas, Rita Elizabeth Moreira Lacroix, Claire Ferrer, Suzana Ramos Oliveira, Rone Peterson Cerqueira Cravo, Elaine Andrade Alves, André Pinheiro Ribeiro Grassi, Maria Fernanda Rios |
| author_role |
author |
| author2 |
Mascarenhas, Rita Elizabeth Moreira Lacroix, Claire Ferrer, Suzana Ramos Oliveira, Rone Peterson Cerqueira Cravo, Elaine Andrade Alves, André Pinheiro Ribeiro Grassi, Maria Fernanda Rios |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Oliveira, Paula Matos Mascarenhas, Rita Elizabeth Moreira Lacroix, Claire Ferrer, Suzana Ramos Oliveira, Rone Peterson Cerqueira Cravo, Elaine Andrade Alves, André Pinheiro Ribeiro Grassi, Maria Fernanda Rios |
| dc.subject.en.pt_BR.fl_str_mv |
HIV Candida Candidiasis Vulvovaginal |
| topic |
HIV Candida Candidiasis Vulvovaginal Infecções Oportunistas Relacionadas com a AIDS/microbiologia Candida/isolamento & purificação Candidíase Vulvovaginal/microbiologia Infecções Oportunistas Relacionadas com a AIDS/diagnóstico Adulto Antifúngicos/farmacologia Brasil Candida/classificação Candida/efeitos de drogas Candidíase Vulvovaginal/diagnóstico Feminino Humanos Testes de Sensibilidade Microbiana Membrana Mucosa/microbiologia Prevalência Vagina/microbiologia |
| dc.subject.decs.pt_BR.fl_str_mv |
Infecções Oportunistas Relacionadas com a AIDS/microbiologia Candida/isolamento & purificação Candidíase Vulvovaginal/microbiologia Infecções Oportunistas Relacionadas com a AIDS/diagnóstico Adulto Antifúngicos/farmacologia Brasil Candida/classificação Candida/efeitos de drogas Candidíase Vulvovaginal/diagnóstico Feminino Humanos Testes de Sensibilidade Microbiana Membrana Mucosa/microbiologia Prevalência Vagina/microbiologia |
| description |
Escola Bahiana de Medicina e Saúde Pública. Salvador, BA, Brasil |
| publishDate |
2011 |
| dc.date.issued.fl_str_mv |
2011 |
| dc.date.accessioned.fl_str_mv |
2014-10-03T17:34:45Z |
| dc.date.available.fl_str_mv |
2014-10-03T17:34:45Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
OLIVEIRA, P. M. et al. Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. Brazilian Journal of Infectious Diseases, v. 15, n. 3, p. 239-244, 2011. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/8496 |
| dc.identifier.issn.none.fl_str_mv |
1678-4391 |
| identifier_str_mv |
OLIVEIRA, P. M. et al. Candida species isolated from the vaginal mucosa of HIV-infected women in Salvador, Bahia, Brazil. Brazilian Journal of Infectious Diseases, v. 15, n. 3, p. 239-244, 2011. 1678-4391 |
| url |
https://www.arca.fiocruz.br/handle/icict/8496 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Elsevier Editora Ltda |
| publisher.none.fl_str_mv |
Elsevier Editora Ltda |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
| instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
| instacron_str |
FIOCRUZ |
| institution |
FIOCRUZ |
| reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
| collection |
Repositório Institucional da FIOCRUZ (ARCA) |
| bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/8496/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/8496/2/Oliveira%20PM%20Candida%20species....pdf https://www.arca.fiocruz.br/bitstream/icict/8496/3/Oliveira%20PM%20Candida%20species....pdf.txt |
| bitstream.checksum.fl_str_mv |
7d48279ffeed55da8dfe2f8e81f3b81f 2ecc5beb865c4485a2faea6effe9c4ae f909f405622e2fcf8fe654f6fb08fdb7 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
| repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
| _version_ |
1813009120730546176 |