Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/34439 |
Resumo: | André Japiassu. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. |
id |
CRUZ_93472d382b7891902bc2bffe4db907f3 |
---|---|
oai_identifier_str |
oai:www.arca.fiocruz.br:icict/34439 |
network_acronym_str |
CRUZ |
network_name_str |
Repositório Institucional da FIOCRUZ (ARCA) |
repository_id_str |
2135 |
spelling |
Machado, Flavia R.Ferreira, Elaine M.Sousa, Juliana LubarinoSilva, CarlaSchippers, PierrePereira, AdrianoCardoso, Ilusca M.Salomão, ReinaldoJapiassu, AndreAkamine, NelsonMazza, Bruno F.Assunção, Murillo S. C.Fernandes, Haggeas S.Bossa, AlineMonteiro, Mariana B.Caixeita, NoemiAzevedo, Luciano C. P.Silva, Eliezer2019-07-26T13:15:21Z2019-07-26T13:15:21Z2017MACHADO, Flavia R. et al. Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients. Critical Care Medicine, v. 45, n. 10, p. 1650-1659, Oct. 2017.0090-3493https://www.arca.fiocruz.br/handle/icict/3443910.1097/CCM.00000000000025851530-0293André Japiassu. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-07-26Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Latin American Sepsis Institute. São Paulo, SP, Brazil.Objective: We aimed to assess the results of a quality improvement initiative in sepsis in an emerging setting and to analyze it according to the institutions’ main source of income (public or private). Design: Retrospective analysis of the Latin American Sepsis Institute database from 2005 to 2014. Settings: Brazilian public and private institutions. Patients: Patients with sepsis admitted in the participant institutions. Interventions: The quality improvement initiative was based on a multifaceted intervention. The institutions were instructed to collect data on 6-hour bundle compliance and outcomes in patients with sepsis in all hospital settings. Outcomes and compliance was measured for eight periods of 6 months each, starting at the time of the enrollment in the intervention. The primary outcomes were hospital mortality and compliance with 6-hour bundle. Measurements and Main Results: We included 21,103 patients; 9,032 from public institutions and 12,071 from private institutions. Comparing the first period with the eigth period, compliance with the 6-hour bundle increased from 13.5% to 58.2% in the private institutions (p < 0.0001) and from 7.4% to 15.7% in the public institutions (p < 0.0001). Mortality rates significantly decreased throughout the program in private institutions, from 47.6% to 27.2% in the eighth period (adjusted odds ratio, 0.45; 95% CI, 0.32–0.64). However, in the public hospitals, mortality diminished significantly only in the first two periods. Conclusion: This quality improvement initiative in sepsis in an emerging country was associated with a reduction in mortality and with improved compliance with quality indicators. However, this reduction was sustained only in private institutions.engLippincott, Williams & WilkinsQuality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patientsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMortalitySepsis bundlesSepsisSeptic shockQuality improvementinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/34439/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Machado_Flavia_etal_INI_2017.pdfve_Machado_Flavia_etal_INI_2017.pdfapplication/pdf364785https://www.arca.fiocruz.br/bitstream/icict/34439/2/ve_Machado_Flavia_etal_INI_2017.pdfae2c5397a3467916a7e133936837eccaMD52TEXTve_Machado_Flavia_etal_INI_2017.pdf.txtve_Machado_Flavia_etal_INI_2017.pdf.txtExtracted texttext/plain52303https://www.arca.fiocruz.br/bitstream/icict/34439/3/ve_Machado_Flavia_etal_INI_2017.pdf.txtff734f4d29eb4ab1eccd41183c02ef4dMD53icict/344392021-03-24 16:32:34.744oai:www.arca.fiocruz.br:icict/34439Q0VTU8ODTyBOw4NPIEVYQ0xVU0lWQSBERSBESVJFSVRPUyBBVVRPUkFJUw0KDQpKYW5hw61uYSBOYXNjaW1lbnRvLCBDUEY6IDAxNC41MDkuNTI3LTQ3LCB2aW5jdWxhZG8gYSBJTkkgLSBJbnN0aXR1dG8gTmFjaW9uYWwgZGUgSW5mZWN0b2xvZ2lhIEV2YW5kcm8gQ2hhZ2FzCgpBbyBhY2VpdGFyIG9zIFRFUk1PUyBlIENPTkRJw4fDlUVTIGRlc3RhIENFU1PDg08sIG8gQVVUT1IgZS9vdSBUSVRVTEFSIGRlIGRpcmVpdG9zCmF1dG9yYWlzIHNvYnJlIGEgT0JSQSBkZSBxdWUgdHJhdGEgZXN0ZSBkb2N1bWVudG86CgooMSkgQ0VERSBlIFRSQU5TRkVSRSwgdG90YWwgZSBncmF0dWl0YW1lbnRlLCDDoCBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVosIGVtCmNhcsOhdGVyIHBlcm1hbmVudGUsIGlycmV2b2fDoXZlbCBlIE7Dg08gRVhDTFVTSVZPLCB0b2RvcyBvcyBkaXJlaXRvcyBwYXRyaW1vbmlhaXMgTsODTwpDT01FUkNJQUlTIGRlIHV0aWxpemHDp8OjbyBkYSBPQlJBIGFydMOtc3RpY2EgZS9vdSBjaWVudMOtZmljYSBpbmRpY2FkYSBhY2ltYSwgaW5jbHVzaXZlIG9zIGRpcmVpdG9zCmRlIHZveiBlIGltYWdlbSB2aW5jdWxhZG9zIMOgIE9CUkEsIGR1cmFudGUgdG9kbyBvIHByYXpvIGRlIGR1cmHDp8OjbyBkb3MgZGlyZWl0b3MgYXV0b3JhaXMsIGVtCnF1YWxxdWVyIGlkaW9tYSBlIGVtIHRvZG9zIG9zIHBhw61zZXM7CgooMikgQUNFSVRBIHF1ZSBhIGNlc3PDo28gdG90YWwgbsOjbyBleGNsdXNpdmEsIHBlcm1hbmVudGUgZSBpcnJldm9nw6F2ZWwgZG9zIGRpcmVpdG9zIGF1dG9yYWlzCnBhdHJpbW9uaWFpcyBuw6NvIGNvbWVyY2lhaXMgZGUgdXRpbGl6YcOnw6NvIGRlIHF1ZSB0cmF0YSBlc3RlIGRvY3VtZW50byBpbmNsdWksIGV4ZW1wbGlmaWNhdGl2YW1lbnRlLApvcyBkaXJlaXRvcyBkZSBkaXNwb25pYmlsaXphw6fDo28gZSBjb211bmljYcOnw6NvIHDDumJsaWNhIGRhIE9CUkEsIGVtIHF1YWxxdWVyIG1laW8gb3UgdmXDrWN1bG8sCmluY2x1c2l2ZSBlbSBSZXBvc2l0w7NyaW9zIERpZ2l0YWlzLCBiZW0gY29tbyBvcyBkaXJlaXRvcyBkZSByZXByb2R1w6fDo28sIGV4aWJpw6fDo28sIGV4ZWN1w6fDo28sCmRlY2xhbWHDp8OjbywgcmVjaXRhw6fDo28sIGV4cG9zacOnw6NvLCBhcnF1aXZhbWVudG8sIGluY2x1c8OjbyBlbSBiYW5jbyBkZSBkYWRvcywgcHJlc2VydmHDp8OjbywgZGlmdXPDo28sCmRpc3RyaWJ1acOnw6NvLCBkaXZ1bGdhw6fDo28sIGVtcHLDqXN0aW1vLCB0cmFkdcOnw6NvLCBkdWJsYWdlbSwgbGVnZW5kYWdlbSwgaW5jbHVzw6NvIGVtIG5vdmFzIG9icmFzIG91CmNvbGV0w6JuZWFzLCByZXV0aWxpemHDp8OjbywgZWRpw6fDo28sIHByb2R1w6fDo28gZGUgbWF0ZXJpYWwgZGlkw6F0aWNvIGUgY3Vyc29zIG91IHF1YWxxdWVyIGZvcm1hIGRlCnV0aWxpemHDp8OjbyBuw6NvIGNvbWVyY2lhbDsKCigzKSBSRUNPTkhFQ0UgcXVlIGEgY2Vzc8OjbyBhcXVpIGVzcGVjaWZpY2FkYSBjb25jZWRlIMOgIEZJT0NSVVogLSBGVU5EQcOHw4NPIE9TV0FMRE8KQ1JVWiBvIGRpcmVpdG8gZGUgYXV0b3JpemFyIHF1YWxxdWVyIHBlc3NvYSDigJMgZsOtc2ljYSBvdSBqdXLDrWRpY2EsIHDDumJsaWNhIG91IHByaXZhZGEsIG5hY2lvbmFsIG91CmVzdHJhbmdlaXJhIOKAkyBhIGFjZXNzYXIgZSB1dGlsaXphciBhbXBsYW1lbnRlIGEgT0JSQSwgc2VtIGV4Y2x1c2l2aWRhZGUsIHBhcmEgcXVhaXNxdWVyCmZpbmFsaWRhZGVzIG7Do28gY29tZXJjaWFpczsKCig0KSBERUNMQVJBIHF1ZSBhIG9icmEgw6kgY3JpYcOnw6NvIG9yaWdpbmFsIGUgcXVlIMOpIG8gdGl0dWxhciBkb3MgZGlyZWl0b3MgYXF1aSBjZWRpZG9zIGUgYXV0b3JpemFkb3MsCnJlc3BvbnNhYmlsaXphbmRvLXNlIGludGVncmFsbWVudGUgcGVsbyBjb250ZcO6ZG8gZSBvdXRyb3MgZWxlbWVudG9zIHF1ZSBmYXplbSBwYXJ0ZSBkYSBPQlJBLAppbmNsdXNpdmUgb3MgZGlyZWl0b3MgZGUgdm96IGUgaW1hZ2VtIHZpbmN1bGFkb3Mgw6AgT0JSQSwgb2JyaWdhbmRvLXNlIGEgaW5kZW5pemFyIHRlcmNlaXJvcyBwb3IKZGFub3MsIGJlbSBjb21vIGluZGVuaXphciBlIHJlc3NhcmNpciBhIEZJT0NSVVogLSBGVU5EQcOHw4NPIE9TV0FMRE8gQ1JVWiBkZQpldmVudHVhaXMgZGVzcGVzYXMgcXVlIHZpZXJlbSBhIHN1cG9ydGFyLCBlbSByYXrDo28gZGUgcXVhbHF1ZXIgb2ZlbnNhIGEgZGlyZWl0b3MgYXV0b3JhaXMgb3UKZGlyZWl0b3MgZGUgdm96IG91IGltYWdlbSwgcHJpbmNpcGFsbWVudGUgbm8gcXVlIGRpeiByZXNwZWl0byBhIHBsw6FnaW8gZSB2aW9sYcOnw7VlcyBkZSBkaXJlaXRvczsKCig1KSBBRklSTUEgcXVlIGNvbmhlY2UgYSBQb2zDrXRpY2EgSW5zdGl0dWNpb25hbCBkZSBBY2Vzc28gQWJlcnRvIGRhIEZJT0NSVVogLSBGVU5EQcOHw4NPCk9TV0FMRE8gQ1JVWiBlIGFzIGRpcmV0cml6ZXMgcGFyYSBvIGZ1bmNpb25hbWVudG8gZG8gcmVwb3NpdMOzcmlvIGluc3RpdHVjaW9uYWwgQVJDQS4KCkEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVogcmVzZXJ2YQpleGNsdXNpdmFtZW50ZSBhbyBBVVRPUiBvcyBkaXJlaXRvcyBtb3JhaXMgZSBvcyB1c29zIGNvbWVyY2lhaXMgc29icmUgYXMgb2JyYXMgZGUgc3VhIGF1dG9yaWEKZS9vdSB0aXR1bGFyaWRhZGUsIHNlbmRvIG9zIHRlcmNlaXJvcyB1c3XDoXJpb3MgcmVzcG9uc8OhdmVpcyBwZWxhIGF0cmlidWnDp8OjbyBkZSBhdXRvcmlhIGUgbWFudXRlbsOnw6NvCmRhIGludGVncmlkYWRlIGRhIE9CUkEgZW0gcXVhbHF1ZXIgdXRpbGl6YcOnw6NvLgoKQSBQb2zDrXRpY2EgSW5zdGl0dWNpb25hbCBkZSBBY2Vzc28gQWJlcnRvIGRhIEZJT0NSVVogLSBGVU5EQcOHw4NPIE9TV0FMRE8gQ1JVWgpyZXNwZWl0YSBvcyBjb250cmF0b3MgZSBhY29yZG9zIHByZWV4aXN0ZW50ZXMgZG9zIEF1dG9yZXMgY29tIHRlcmNlaXJvcywgY2FiZW5kbyBhb3MgQXV0b3JlcwppbmZvcm1hciDDoCBJbnN0aXR1acOnw6NvIGFzIGNvbmRpw6fDtWVzIGUgb3V0cmFzIHJlc3RyacOnw7VlcyBpbXBvc3RhcyBwb3IgZXN0ZXMgaW5zdHJ1bWVudG9zLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:34Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
title |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
spellingShingle |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients Machado, Flavia R. Mortality Sepsis bundles Sepsis Septic shock Quality improvement |
title_short |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
title_full |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
title_fullStr |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
title_full_unstemmed |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
title_sort |
Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients |
author |
Machado, Flavia R. |
author_facet |
Machado, Flavia R. Ferreira, Elaine M. Sousa, Juliana Lubarino Silva, Carla Schippers, Pierre Pereira, Adriano Cardoso, Ilusca M. Salomão, Reinaldo Japiassu, Andre Akamine, Nelson Mazza, Bruno F. Assunção, Murillo S. C. Fernandes, Haggeas S. Bossa, Aline Monteiro, Mariana B. Caixeita, Noemi Azevedo, Luciano C. P. Silva, Eliezer |
author_role |
author |
author2 |
Ferreira, Elaine M. Sousa, Juliana Lubarino Silva, Carla Schippers, Pierre Pereira, Adriano Cardoso, Ilusca M. Salomão, Reinaldo Japiassu, Andre Akamine, Nelson Mazza, Bruno F. Assunção, Murillo S. C. Fernandes, Haggeas S. Bossa, Aline Monteiro, Mariana B. Caixeita, Noemi Azevedo, Luciano C. P. Silva, Eliezer |
author2_role |
author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Machado, Flavia R. Ferreira, Elaine M. Sousa, Juliana Lubarino Silva, Carla Schippers, Pierre Pereira, Adriano Cardoso, Ilusca M. Salomão, Reinaldo Japiassu, Andre Akamine, Nelson Mazza, Bruno F. Assunção, Murillo S. C. Fernandes, Haggeas S. Bossa, Aline Monteiro, Mariana B. Caixeita, Noemi Azevedo, Luciano C. P. Silva, Eliezer |
dc.subject.en.pt_BR.fl_str_mv |
Mortality Sepsis bundles Sepsis Septic shock Quality improvement |
topic |
Mortality Sepsis bundles Sepsis Septic shock Quality improvement |
description |
André Japiassu. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2019-07-26T13:15:21Z |
dc.date.available.fl_str_mv |
2019-07-26T13:15:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MACHADO, Flavia R. et al. Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients. Critical Care Medicine, v. 45, n. 10, p. 1650-1659, Oct. 2017. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/34439 |
dc.identifier.issn.pt_BR.fl_str_mv |
0090-3493 |
dc.identifier.doi.none.fl_str_mv |
10.1097/CCM.0000000000002585 |
dc.identifier.eissn.none.fl_str_mv |
1530-0293 |
identifier_str_mv |
MACHADO, Flavia R. et al. Quality improvement initiatives in sepsis in an emerging country: does the institution's mainsource of income influence the results? An analysis of 21,103 patients. Critical Care Medicine, v. 45, n. 10, p. 1650-1659, Oct. 2017. 0090-3493 10.1097/CCM.0000000000002585 1530-0293 |
url |
https://www.arca.fiocruz.br/handle/icict/34439 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
instname_str |
Fundação Oswaldo Cruz (FIOCRUZ) |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
reponame_str |
Repositório Institucional da FIOCRUZ (ARCA) |
collection |
Repositório Institucional da FIOCRUZ (ARCA) |
bitstream.url.fl_str_mv |
https://www.arca.fiocruz.br/bitstream/icict/34439/1/license.txt https://www.arca.fiocruz.br/bitstream/icict/34439/2/ve_Machado_Flavia_etal_INI_2017.pdf https://www.arca.fiocruz.br/bitstream/icict/34439/3/ve_Machado_Flavia_etal_INI_2017.pdf.txt |
bitstream.checksum.fl_str_mv |
79178e5f2a0eb066867a274556814938 ae2c5397a3467916a7e133936837ecca ff734f4d29eb4ab1eccd41183c02ef4d |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ) |
repository.mail.fl_str_mv |
repositorio.arca@fiocruz.br |
_version_ |
1798324749104840704 |