Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season

Detalhes bibliográficos
Autor(a) principal: Resende, Paola Cristina
Data de Publicação: 2015
Outros Autores: Motta, Fernando Couto, Born, Priscila Silva, Miranda, Milene, Siqueira, Marilda Agudo Mendonça Teixeira de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/12244
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.
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spelling Resende, Paola CristinaMotta, Fernando CoutoBorn, Priscila SilvaMiranda, MileneSiqueira, Marilda Agudo Mendonça Teixeira de2015-11-16T16:37:22Z2015-11-16T16:37:22Z2015RESENDE, Paola Cristina; et al. Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season. Mem Inst Oswaldo Cruz, v.110, n.1, p.148-150, Feb. 2015.0074-0276https://www.arca.fiocruz.br/handle/icict/1224410.1590/0074-027601404121678-8060engFundação Oswaldo CruzWhole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 seasoninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.The influenza A(H3N2) virus has circulated worldwide for almost five decades and is the dominant subtype in most seasonal influenza epidemics, as occurred in the 2014 season in South America. In this study we evaluate five whole genome sequences of influenza A(H3N2) viruses detected in patients with mild illness collected from January March 2014. To sequence the genomes, a new generation sequencing (NGS) protocol was performed using the Ion Torrent PGM platform. In addition to analysing the common genes, haemagglutinin, neuraminidase and matrix, our work also comprised internal genes. This was the first report of a whole genome analysis with Brazilian influenza A(H3N2) samples. Considerable amino acid variability was encountered in all gene segments, demonstrating the importance of studying the internal genes. NGS of whole genomes in this study will facilitate deeper virus characterisation, contributing to the improvement of influenza strain surveillance in Brazil.InfluenzaH3N2Ion TorrentNGSVírus da Influenza AVírus da Influenza A Subtipo H3N2Brasilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/12244/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALfernando_motta_etal_IOC_2015.pdffernando_motta_etal_IOC_2015.pdfapplication/pdf222306https://www.arca.fiocruz.br/bitstream/icict/12244/2/fernando_motta_etal_IOC_2015.pdf421b5d30d1c8e3eec96dc3dda24f771bMD52TEXTfernando_motta_etal_IOC_2015.pdf.txtfernando_motta_etal_IOC_2015.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
title Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
spellingShingle Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
Resende, Paola Cristina
Influenza
H3N2
Ion Torrent
NGS
Vírus da Influenza A
Vírus da Influenza A Subtipo H3N2
Brasil
title_short Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
title_full Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
title_fullStr Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
title_full_unstemmed Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
title_sort Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season
author Resende, Paola Cristina
author_facet Resende, Paola Cristina
Motta, Fernando Couto
Born, Priscila Silva
Miranda, Milene
Siqueira, Marilda Agudo Mendonça Teixeira de
author_role author
author2 Motta, Fernando Couto
Born, Priscila Silva
Miranda, Milene
Siqueira, Marilda Agudo Mendonça Teixeira de
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Resende, Paola Cristina
Motta, Fernando Couto
Born, Priscila Silva
Miranda, Milene
Siqueira, Marilda Agudo Mendonça Teixeira de
dc.subject.en.pt_BR.fl_str_mv Influenza
H3N2
Ion Torrent
NGS
topic Influenza
H3N2
Ion Torrent
NGS
Vírus da Influenza A
Vírus da Influenza A Subtipo H3N2
Brasil
dc.subject.decs.pt_BR.fl_str_mv Vírus da Influenza A
Vírus da Influenza A Subtipo H3N2
Brasil
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Vírus Respiratórios e do Sarampo. Rio de Janeiro, RJ, Brasil.
publishDate 2015
dc.date.accessioned.fl_str_mv 2015-11-16T16:37:22Z
dc.date.available.fl_str_mv 2015-11-16T16:37:22Z
dc.date.issued.fl_str_mv 2015
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv RESENDE, Paola Cristina; et al. Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season. Mem Inst Oswaldo Cruz, v.110, n.1, p.148-150, Feb. 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/12244
dc.identifier.issn.none.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/0074-02760140412
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv RESENDE, Paola Cristina; et al. Whole-genome sequences of influenza A(H3N2) viruses isolated from Brazilian patients with mild illness during the 2014 season. Mem Inst Oswaldo Cruz, v.110, n.1, p.148-150, Feb. 2015.
0074-0276
10.1590/0074-02760140412
1678-8060
url https://www.arca.fiocruz.br/handle/icict/12244
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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