Immune response in COVID-19: what do we currently know?

Detalhes bibliográficos
Autor(a) principal: Oliveira, Daniela Silva de
Data de Publicação: 2020
Outros Autores: Medeiros, Nayara Ingrid, Gomes, Juliana de Assis Silva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/43403
Resumo: Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brasil.
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spelling Oliveira, Daniela Silva deMedeiros, Nayara IngridGomes, Juliana de Assis Silva2020-09-16T16:04:01Z2020-09-16T16:04:01Z2020OLIVEIRA, Daniela Silva de; MEDEIROS, Nayara Ingrid; GOMES, Juliana de Assis Silva. Immune response in COVID-19: what do we currently know? Microbial Pathogenesis, p. 1-33, 2020.0882-4010https://www.arca.fiocruz.br/handle/icict/4340310.1016/j.micpath.2020.104484engScience Directhttps://www.arca.fiocruz.br/handle/icict/51725COVID-19SARS-CoV-2COVID-19SARS-CoV-2Immune response in COVID-19: what do we currently know?info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brasil.Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Instituto René Rachou. Imunologia Celular e Molecular. Belo Horizonte, MG, BrasilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brasil.In 2002/2003 there was a pandemic denominate SARS (severe acute respiratory 20 syndrome), caused by the SARS-CoV virus that belongs to the genera Betacoranavirus and the family Coronaviridae, generally responsible for influenza infections. In mid of 2019, a new disease by the coronavirus named by COVID-19 (SARS-CoV-2) emerged, both infections have flu symptoms, however they are infections that variable intensity, being medium to severe. In medium infections individuals have the virus and exhibit symptoms, however hospitalization is not necessary, in severe infections, individuals are hospitalized, have high pathology and in some cases progress to death. The virus is formed by simple positive RNA, enveloped, non-segmented, and presenting the largest genome of viruses constituting 32Kb, consisting of envelope proteins, membrane, nucleo capsid and spike protein, which is essential in the interaction with the host cells. As for the origin of this virus, research has been intensified to determine this paradox and although the similarity with SARS-CoV, this virus did not has necessarily the same place of origin. As for the immune system, it is currently unknown how this new virus interacts. In this brief review, we demonstrate important considerations about the responses to this infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/43403/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALImmune response in COVID-19_ What do we currently know_.pdfImmune response in COVID-19_ What do we currently know_.pdfapplication/pdf767113https://www.arca.fiocruz.br/bitstream/icict/43403/2/Immune%20response%20in%20COVID-19_%20What%20do%20we%20currently%20know_.pdfdd692b18e26c5acdd155e06db72f2245MD52TEXTImmune response in COVID-19_ What do we currently know_.pdf.txtImmune response in COVID-19_ What do we currently know_.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Immune response in COVID-19: what do we currently know?
title Immune response in COVID-19: what do we currently know?
spellingShingle Immune response in COVID-19: what do we currently know?
Oliveira, Daniela Silva de
COVID-19
SARS-CoV-2
COVID-19
SARS-CoV-2
title_short Immune response in COVID-19: what do we currently know?
title_full Immune response in COVID-19: what do we currently know?
title_fullStr Immune response in COVID-19: what do we currently know?
title_full_unstemmed Immune response in COVID-19: what do we currently know?
title_sort Immune response in COVID-19: what do we currently know?
author Oliveira, Daniela Silva de
author_facet Oliveira, Daniela Silva de
Medeiros, Nayara Ingrid
Gomes, Juliana de Assis Silva
author_role author
author2 Medeiros, Nayara Ingrid
Gomes, Juliana de Assis Silva
author2_role author
author
dc.contributor.author.fl_str_mv Oliveira, Daniela Silva de
Medeiros, Nayara Ingrid
Gomes, Juliana de Assis Silva
dc.subject.other.pt_BR.fl_str_mv COVID-19
SARS-CoV-2
topic COVID-19
SARS-CoV-2
COVID-19
SARS-CoV-2
dc.subject.en.pt_BR.fl_str_mv COVID-19
SARS-CoV-2
description Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-09-16T16:04:01Z
dc.date.available.fl_str_mv 2020-09-16T16:04:01Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, Daniela Silva de; MEDEIROS, Nayara Ingrid; GOMES, Juliana de Assis Silva. Immune response in COVID-19: what do we currently know? Microbial Pathogenesis, p. 1-33, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/43403
dc.identifier.issn.pt_BR.fl_str_mv 0882-4010
dc.identifier.doi.none.fl_str_mv 10.1016/j.micpath.2020.104484
identifier_str_mv OLIVEIRA, Daniela Silva de; MEDEIROS, Nayara Ingrid; GOMES, Juliana de Assis Silva. Immune response in COVID-19: what do we currently know? Microbial Pathogenesis, p. 1-33, 2020.
0882-4010
10.1016/j.micpath.2020.104484
url https://www.arca.fiocruz.br/handle/icict/43403
dc.language.iso.fl_str_mv eng
language eng
dc.relation.hasversion.pt_BR.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51725
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Science Direct
publisher.none.fl_str_mv Science Direct
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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