Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study

Detalhes bibliográficos
Autor(a) principal: Jordão, Paula Moskovics
Data de Publicação: 2020
Outros Autores: Russomano, Fábio Bastos, Gerbauld, Gabriella Tostes, Andrade, Cecília Vianna de, Osorio, Clarice Fraga Esteves Maciel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42539
Resumo: Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.
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spelling Jordão, Paula MoskovicsRussomano, Fábio BastosGerbauld, Gabriella TostesAndrade, Cecília Vianna deOsorio, Clarice Fraga Esteves Maciel2020-08-04T19:26:01Z2020-08-04T19:26:01Z2020Jordão PM, Russomano FB, Gerbauld GT, Andrade CV, Osorio CFEM. Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study. Sao Paulo Med J. 2020;138(1):47-53. doi:10.1590/1516-3180.2019.0435.R1.191120191516-3180https://www.arca.fiocruz.br/handle/icict/4253910.1590/1516-3180.2019.0435.R1.19112019engAssociação Paulista de Medicina - APMUterine cervical neoplasmsColposcopyMass screening; PathologySensitivity and specificityEndocervical lesionsEndocervical brushingType 3 transformation zoneAccuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.Background: Cervical cancer screening in Brazil is done using Pap smears. Women who are most likely to have a preinvasive lesion or cervical cancer are immediately referred for colposcopy. Objective: The aim of this study was to evaluate the diagnostic performance of endocervical cytological tests in diagnosing preinvasive cervical lesions in women with initial high-grade squamous intraepithelial lesions (HSIL), or atypical squamous cells in which high-grade lesions could not be ruled out (ASC-H), or atypical glandular cells (AGC), and whose colposcopy did not show any abnormalities, with no fully visible transformation zone (types 2 and 3). Design and setting: Retrospective observational study conducted in Rio de Janeiro, Brazil. Methods: Data from women who came to the cervical pathology outpatient clinic between January 2012 and April 2017 were analyzed. The results from endocervical cytological tests were compared with the final diagnosis, which was obtained through examination of a surgical specimen or, among women who did not undergo an excisional procedure, after cytological and colposcopic follow-up for two years. Results: We included 78 women. The sensitivity of endocervical cytological tests was 72.7%; specificity 98.5%; positive and negative predictive values 88.9% and 95.6%, respectively; and positive and negative likelihood ratios 48.7 and 0.28. Conclusion: Endocervical cytological tests are simple, inexpensive and noninvasive, and form a reliable method for determining management among patients with HSIL, ASC-H and AGC cytological findings and negative colposcopic findings without visualization of the squamocolumnar junction.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/42539/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL1806-9460-spmj-138-01-47.pdf1806-9460-spmj-138-01-47.pdfapplication/pdf209524https://www.arca.fiocruz.br/bitstream/icict/42539/2/1806-9460-spmj-138-01-47.pdf33e8d0ecca968092927f388f7fb04540MD52TEXT1806-9460-spmj-138-01-47.pdf.txt1806-9460-spmj-138-01-47.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
title Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
spellingShingle Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
Jordão, Paula Moskovics
Uterine cervical neoplasms
Colposcopy
Mass screening; Pathology
Sensitivity and specificity
Endocervical lesions
Endocervical brushing
Type 3 transformation zone
title_short Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
title_full Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
title_fullStr Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
title_full_unstemmed Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
title_sort Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study
author Jordão, Paula Moskovics
author_facet Jordão, Paula Moskovics
Russomano, Fábio Bastos
Gerbauld, Gabriella Tostes
Andrade, Cecília Vianna de
Osorio, Clarice Fraga Esteves Maciel
author_role author
author2 Russomano, Fábio Bastos
Gerbauld, Gabriella Tostes
Andrade, Cecília Vianna de
Osorio, Clarice Fraga Esteves Maciel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Jordão, Paula Moskovics
Russomano, Fábio Bastos
Gerbauld, Gabriella Tostes
Andrade, Cecília Vianna de
Osorio, Clarice Fraga Esteves Maciel
dc.subject.mesh.pt_BR.fl_str_mv Uterine cervical neoplasms
Colposcopy
Mass screening; Pathology
Sensitivity and specificity
topic Uterine cervical neoplasms
Colposcopy
Mass screening; Pathology
Sensitivity and specificity
Endocervical lesions
Endocervical brushing
Type 3 transformation zone
dc.subject.en.pt_BR.fl_str_mv Endocervical lesions
Endocervical brushing
Type 3 transformation zone
description Fundação Oswaldo Cruz. Instituto Nacional da Saúde da Mulher da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ. Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-08-04T19:26:01Z
dc.date.available.fl_str_mv 2020-08-04T19:26:01Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Jordão PM, Russomano FB, Gerbauld GT, Andrade CV, Osorio CFEM. Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study. Sao Paulo Med J. 2020;138(1):47-53. doi:10.1590/1516-3180.2019.0435.R1.19112019
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42539
dc.identifier.issn.pt_BR.fl_str_mv 1516-3180
dc.identifier.doi.none.fl_str_mv 10.1590/1516-3180.2019.0435.R1.19112019
identifier_str_mv Jordão PM, Russomano FB, Gerbauld GT, Andrade CV, Osorio CFEM. Accuracy of endocervical cytological tests in diagnosing preinvasive lesions of the cervical canal in patients with type 3 transformation zone: a retrospective observational study. Sao Paulo Med J. 2020;138(1):47-53. doi:10.1590/1516-3180.2019.0435.R1.19112019
1516-3180
10.1590/1516-3180.2019.0435.R1.19112019
url https://www.arca.fiocruz.br/handle/icict/42539
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/42539/1/license.txt
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https://www.arca.fiocruz.br/bitstream/icict/42539/3/1806-9460-spmj-138-01-47.pdf.txt
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