First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/28844 |
Resumo: | Brazilian Research councils: (CNPq-140152/2014-8; Conselho Nacional de Desenvolvimento Cientíıfico e Tecnológico. This is my PhD fellowship grant which is the result of collaboration between Brazil and Africa), (FAPESP-2013/08135-2; Fundação de Amparo a Pesquisa do Estado de São Paulo), (FINEP-1387/10; Ministério da Ciencia, Technologia, Inovações e Comunicações-Financiadora de Estudo e Projetos (Empresa Brasileira de inovação e Pesquisas), and the Centre de Prise en Charge Medicale Integree du Nourrisson et de la Femme Enceinte atteints de Drépanocytose (CPMINFED), the national instititute of sickle cell disease, the Ministry of Health and the Ministry of hight Education, Benin, Afrique and Agence National de Transfusion Sanguine (ANTS), the Ministry of Health and the Ministry of hight Education, Benin, Afrique. |
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Amoussa, Adjile Edjide RoukiyathKashima, SimoneDjobessi, DidierBarreto, Fernanda KhouriDavou, DeniseBigot, AndreAnani, LudovicLourenco, JoseGiovanetti, MartaSabino, EsterRahimy, Mohamed CherifAlcantara, Luiz Carlos Júnior2018-09-18T12:10:17Z2018-09-18T12:10:17Z2018AMOUSSA, A. E. R. et al. First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety. ISBT Science Series, p. 1–6, 2018.1751-2816https://www.arca.fiocruz.br/handle/icict/28844Brazilian Research councils: (CNPq-140152/2014-8; Conselho Nacional de Desenvolvimento Cientíıfico e Tecnológico. This is my PhD fellowship grant which is the result of collaboration between Brazil and Africa), (FAPESP-2013/08135-2; Fundação de Amparo a Pesquisa do Estado de São Paulo), (FINEP-1387/10; Ministério da Ciencia, Technologia, Inovações e Comunicações-Financiadora de Estudo e Projetos (Empresa Brasileira de inovação e Pesquisas), and the Centre de Prise en Charge Medicale Integree du Nourrisson et de la Femme Enceinte atteints de Drépanocytose (CPMINFED), the national instititute of sickle cell disease, the Ministry of Health and the Ministry of hight Education, Benin, Afrique and Agence National de Transfusion Sanguine (ANTS), the Ministry of Health and the Ministry of hight Education, Benin, Afrique.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilHemocentro de Ribeirão Preto. Ribeirão Preto, SP, BrasilService d’Immunologie Banque de Sang. Cotonou, BeninFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilAgence Nationale pour la Transfusion Sanguine. Cotonou, BeninService d’Immunologie Banque de Sang. Cotonou, BeninAgence Nationale pour la Transfusion Sanguine. Cotonou, BeninUniversity of Oxford. Oxford, UKFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilUniversity of São Paulo. São Paulo, BrasilCentre de Prise en Charge M edicale Int egr ee du Nourrisson et de la Femme Enceinte atteints de Drépanocytose. Cotonou, BeninFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilIntroduction Human T-lymphotropic virus (HTLV) is a blood-borne infection that can be transmitted via blood transfusion. Knowing that blood safety can improve blood transfusion to prevent dissemination of viral infections in medical facilities, there is no routine pre-transfusion screening for HTLV in all blood banks in the Republic of Benin. This study aims to estimate the prevalence of HTLV infection in blood donors and describes the characteristics of positive donors. Methods A HTLV prevalence study was carried out by screening 2,035 samples by an enzyme-linked immunoassay obtained from six blood banks located throughout the Republic of Benin. The PCR method was used to confirm and type all the ELISA reactive samples. Results and discussion Twelve subjects, all volunteer blood donors, were found with positive serology confirmed by a specific HTLV type 1 PCR assay, representing an overall seroprevalence of 0 59%. Furthermore, seven subjects were indeterminate for anti-HTLV-1/2 antibody and only one sample was confirmed positive for HTLV type 1 in a PCR reaction. These are the first cases of HTLV detection among blood donors in Benin Republic, whose blood was already transfused to recipients. This result emphasizes that HTLV needs to be considered as a Public Health issue in the Republic of Benin. Conclusion This study reports positive result of HTLV infection among blood donors in the blood banks of Benin Republic in West Africa and highlights the inclusion of screening tests and strategies to reduce its transmission.engWileyDoadores de sangueHTLVPrevalência de HTLVTeste de HTLVBlood donorsHTLVHTLV prevalenceHTLV testingFirst detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safetyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/28844/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAmoussa AE First detection of human....pdfAmoussa AE First detection of 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| dc.title.pt_BR.fl_str_mv |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| title |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| spellingShingle |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety Amoussa, Adjile Edjide Roukiyath Doadores de sangue HTLV Prevalência de HTLV Teste de HTLV Blood donors HTLV HTLV prevalence HTLV testing |
| title_short |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| title_full |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| title_fullStr |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| title_full_unstemmed |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| title_sort |
First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety |
| author |
Amoussa, Adjile Edjide Roukiyath |
| author_facet |
Amoussa, Adjile Edjide Roukiyath Kashima, Simone Djobessi, Didier Barreto, Fernanda Khouri Davou, Denise Bigot, Andre Anani, Ludovic Lourenco, Jose Giovanetti, Marta Sabino, Ester Rahimy, Mohamed Cherif Alcantara, Luiz Carlos Júnior |
| author_role |
author |
| author2 |
Kashima, Simone Djobessi, Didier Barreto, Fernanda Khouri Davou, Denise Bigot, Andre Anani, Ludovic Lourenco, Jose Giovanetti, Marta Sabino, Ester Rahimy, Mohamed Cherif Alcantara, Luiz Carlos Júnior |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Amoussa, Adjile Edjide Roukiyath Kashima, Simone Djobessi, Didier Barreto, Fernanda Khouri Davou, Denise Bigot, Andre Anani, Ludovic Lourenco, Jose Giovanetti, Marta Sabino, Ester Rahimy, Mohamed Cherif Alcantara, Luiz Carlos Júnior |
| dc.subject.other.pt_BR.fl_str_mv |
Doadores de sangue HTLV Prevalência de HTLV Teste de HTLV |
| topic |
Doadores de sangue HTLV Prevalência de HTLV Teste de HTLV Blood donors HTLV HTLV prevalence HTLV testing |
| dc.subject.en.pt_BR.fl_str_mv |
Blood donors HTLV HTLV prevalence HTLV testing |
| description |
Brazilian Research councils: (CNPq-140152/2014-8; Conselho Nacional de Desenvolvimento Cientíıfico e Tecnológico. This is my PhD fellowship grant which is the result of collaboration between Brazil and Africa), (FAPESP-2013/08135-2; Fundação de Amparo a Pesquisa do Estado de São Paulo), (FINEP-1387/10; Ministério da Ciencia, Technologia, Inovações e Comunicações-Financiadora de Estudo e Projetos (Empresa Brasileira de inovação e Pesquisas), and the Centre de Prise en Charge Medicale Integree du Nourrisson et de la Femme Enceinte atteints de Drépanocytose (CPMINFED), the national instititute of sickle cell disease, the Ministry of Health and the Ministry of hight Education, Benin, Afrique and Agence National de Transfusion Sanguine (ANTS), the Ministry of Health and the Ministry of hight Education, Benin, Afrique. |
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2018 |
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2018-09-18T12:10:17Z |
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2018 |
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AMOUSSA, A. E. R. et al. First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety. ISBT Science Series, p. 1–6, 2018. |
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AMOUSSA, A. E. R. et al. First detection of human T-lymphotropic virus in blood donors in Benin shows that testing is required to improve blood safety. ISBT Science Series, p. 1–6, 2018. 1751-2816 |
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