Platelet–leukocyte interactions in the pathogenesis of viral infections

Detalhes bibliográficos
Autor(a) principal: Hottz, Eugenio D.
Data de Publicação: 2021
Outros Autores: Teixeira, Anna Cecíllia Quirino, Merij, Laura Botelho, Pinheiro, Mariana Brandi Mendonça, Rozini, Stephane Vicente, Bozza, Fernando A., Bozza, Patrícia T.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/51037
Resumo: Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
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spelling Hottz, Eugenio D.Teixeira, Anna Cecíllia QuirinoMerij, Laura BotelhoPinheiro, Mariana Brandi MendonçaRozini, Stephane VicenteBozza, Fernando A.Bozza, Patrícia T.2022-02-05T20:56:35Z2022-02-05T20:56:35Z2021HOTTZ, Eugenio D. et al. Platelet–leukocyte interactions in the pathogenesis of viral infections. Platelets,On line, p. 1 - 8, 2021.0953-7104https://www.arca.fiocruz.br/handle/icict/5103710.1080/09537104.2021.19521791369-1635engTaylor & FrancisCOVID-19DenguePlaquetasAgregados de plaquetas-leucócitosHIVInfluenzaCOVID-19PlateletsPlatelet-leukocyte aggregatesDengueHIVInfluenzaPlatelet–leukocyte interactions in the pathogenesis of viral infectionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil.Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em Medicina Intensiva. Rio de Janeiro, RJ, Brasil / Instituto D`Or de Pesquisa e Educação. Medicina Intensiva. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Evolving evidence demonstrates that platelets have major roles in viral syndromes through previously unrecognized viral sensing and effector functions. Activated platelets and increased platelet-leukocyte aggregates are observed in clinical and experimental viral infections. The mechanisms and outcomes of platelet–leukocyte interactions depend on the interacting leukocyte as well as on the pathogen and pathological conditions. In this review, we discuss the mechanisms involved in platelet interactions with leukocytes and its functions during viral infections. We focus on the contributions of human platelet–leukocyte interactions to pathophysiological and protective responses during viral infections of major global health relevance, including acquired immunodeficiency syndrome (AIDS), dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS), influenza pneumonia, and COVID-19.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/51037/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALEugenioHottz_PatricaBozza_etal_IOC_2021.pdfEugenioHottz_PatricaBozza_etal_IOC_2021.pdfapplication/pdf2155384https://www.arca.fiocruz.br/bitstream/icict/51037/2/EugenioHottz_PatricaBozza_etal_IOC_2021.pdf5a14edeca1218f6d343188d607146950MD52icict/510372022-06-24 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dc.title.pt_BR.fl_str_mv Platelet–leukocyte interactions in the pathogenesis of viral infections
title Platelet–leukocyte interactions in the pathogenesis of viral infections
spellingShingle Platelet–leukocyte interactions in the pathogenesis of viral infections
Hottz, Eugenio D.
COVID-19
Dengue
Plaquetas
Agregados de plaquetas-leucócitos
HIV
Influenza
COVID-19
Platelets
Platelet-leukocyte aggregates
Dengue
HIV
Influenza
title_short Platelet–leukocyte interactions in the pathogenesis of viral infections
title_full Platelet–leukocyte interactions in the pathogenesis of viral infections
title_fullStr Platelet–leukocyte interactions in the pathogenesis of viral infections
title_full_unstemmed Platelet–leukocyte interactions in the pathogenesis of viral infections
title_sort Platelet–leukocyte interactions in the pathogenesis of viral infections
author Hottz, Eugenio D.
author_facet Hottz, Eugenio D.
Teixeira, Anna Cecíllia Quirino
Merij, Laura Botelho
Pinheiro, Mariana Brandi Mendonça
Rozini, Stephane Vicente
Bozza, Fernando A.
Bozza, Patrícia T.
author_role author
author2 Teixeira, Anna Cecíllia Quirino
Merij, Laura Botelho
Pinheiro, Mariana Brandi Mendonça
Rozini, Stephane Vicente
Bozza, Fernando A.
Bozza, Patrícia T.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Hottz, Eugenio D.
Teixeira, Anna Cecíllia Quirino
Merij, Laura Botelho
Pinheiro, Mariana Brandi Mendonça
Rozini, Stephane Vicente
Bozza, Fernando A.
Bozza, Patrícia T.
dc.subject.other.pt_BR.fl_str_mv COVID-19
Dengue
Plaquetas
Agregados de plaquetas-leucócitos
HIV
Influenza
topic COVID-19
Dengue
Plaquetas
Agregados de plaquetas-leucócitos
HIV
Influenza
COVID-19
Platelets
Platelet-leukocyte aggregates
Dengue
HIV
Influenza
dc.subject.en.pt_BR.fl_str_mv COVID-19
Platelets
Platelet-leukocyte aggregates
Dengue
HIV
Influenza
description Universidade Federal de Juiz de Fora. Instituto de Ciências Biológicas. Departamento de Bioquímica. Laboratório de Imunotrombose. Juiz de Fora, MG, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-02-05T20:56:35Z
dc.date.available.fl_str_mv 2022-02-05T20:56:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv HOTTZ, Eugenio D. et al. Platelet–leukocyte interactions in the pathogenesis of viral infections. Platelets,On line, p. 1 - 8, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/51037
dc.identifier.issn.pt_BR.fl_str_mv 0953-7104
dc.identifier.doi.none.fl_str_mv 10.1080/09537104.2021.1952179
dc.identifier.eissn.none.fl_str_mv 1369-1635
identifier_str_mv HOTTZ, Eugenio D. et al. Platelet–leukocyte interactions in the pathogenesis of viral infections. Platelets,On line, p. 1 - 8, 2021.
0953-7104
10.1080/09537104.2021.1952179
1369-1635
url https://www.arca.fiocruz.br/handle/icict/51037
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/51037/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/51037/2/EugenioHottz_PatricaBozza_etal_IOC_2021.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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