Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Hauser-Davis, Rachel Ann
Data de Publicação: 2020
Outros Autores: Figueiredo, Livia, Lemos, Leila, Moura, Jailson Fulgêncio de, Rocha, Rafael C. C., Saint Pierre, Tatiana, Ziolli, Roberta L., Siciliano, Salvatore
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/45802
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil / GEMM-Lagos. Araruama, RJ, Brasil.
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spelling Hauser-Davis, Rachel AnnFigueiredo, LiviaLemos, LeilaMoura, Jailson Fulgêncio deRocha, Rafael C. C.Saint Pierre, TatianaZiolli, Roberta L.Siciliano, Salvatore2021-01-25T15:10:23Z2021-01-25T15:10:23Z2020HAUSER-DAVIS, Rachel Ann et al. Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil. Frontiers in Marine Science, v. 7, Article 584195, p. 1-8, Dec. 2020.2296-7745https://www.arca.fiocruz.br/handle/icict/4580210.3389/fmars.2020.584195engFrontiers MediaFracionamento metálico subcelularDesintoxicação metálicaBiodisponibilidadeContaminaçãoOdontocetesSubcellular metal fractionationMetal detoxificationBioavailabilityContaminationSubcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil / GEMM-Lagos. Araruama, RJ, Brasil.Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.GEMM-Lagos. Araruama, RJ, Brasil / Oregon State University. Mammal Institute. Hatfield Marine Science Center. Corvallis, OR, USA.GEMM-Lagos. Araruama, RJ, Brasil / Leibniz Center for Tropical Marine Ecology (ZMT), Systems Ecology Group. Bremen, Germany.Pontifícia Universidade Católica do Rio de Janeiro. Departamento de Química. Rio de Janeiro, RJ, Brasil.Pontifícia Universidade Católica do Rio de Janeiro. Departamento de Química. Rio de Janeiro, RJ, Brasil.Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.GEMM-Lagos. Araruama, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biodiversidade. Rio de Janeiro, RJ, Brasil.Marine mammals are considered excellent ocean health sentinels and are ubiquitously exposed to chemical contaminants worldwide. The Guiana dolphin (Sotalia guianensis) is a near-threatened dolphin species from Brazil with unknown population size data. This indicates the need for assessments regarding deleterious effects that may arise from exposure to chemical contamination, especially metals. After entry in the organism, these compounds are subject to internal subcellular compartmentalization, which in turn alters their bioavailability. However, almost no assessments regarding subcellular metal contents in marine mammals are available. In this context, metal compartmentalization was determined in three subcellular fractions for three toxic elements, Cd, Hg and Pb, by inductively coupled plasma mass spectrometry (ICP-MS) in Guiana dolphin kidney and liver samples from Southeastern Brazil. Differential metal-detoxification mechanisms were observed for the three elements, where metallothionein (MT) detoxification was postulated for only for Pb, while Cd and Hg were poorly associated to MT, and mostly present in the insoluble fraction, indicating low bioavailability. This is the first report on subcellular metal compartmentalization in Guiana dolphins and indicates that critical biochemical detoxification data is obtained through subcellular fraction analyses in marine mammals. This indicates an emerging study field for this type of assessment, which may, in turn, aid in conservation efforts.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/45802/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALRachelAnnDavis_RafaelRocha_etal_IOC_2020.pdfRachelAnnDavis_RafaelRocha_etal_IOC_2020.pdfapplication/pdf990818https://www.arca.fiocruz.br/bitstream/icict/45802/2/RachelAnnDavis_RafaelRocha_etal_IOC_2020.pdf8a15b2ffcaf92c89688b88090cb6c237MD52TEXTRachelAnnDavis_RafaelRocha_etal_IOC_2020.pdf.txtRachelAnnDavis_RafaelRocha_etal_IOC_2020.pdf.txtExtracted texttext/plain46028https://www.arca.fiocruz.br/bitstream/icict/45802/3/RachelAnnDavis_RafaelRocha_etal_IOC_2020.pdf.txtb28dce982dd435b5b24ad8882aa11095MD53icict/458022021-04-16 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dc.title.pt_BR.fl_str_mv Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
title Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
spellingShingle Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
Hauser-Davis, Rachel Ann
Fracionamento metálico subcelular
Desintoxicação metálica
Biodisponibilidade
Contaminação
Odontocetes
Subcellular metal fractionation
Metal detoxification
Bioavailability
Contamination
title_short Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
title_full Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
title_fullStr Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
title_full_unstemmed Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
title_sort Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil
author Hauser-Davis, Rachel Ann
author_facet Hauser-Davis, Rachel Ann
Figueiredo, Livia
Lemos, Leila
Moura, Jailson Fulgêncio de
Rocha, Rafael C. C.
Saint Pierre, Tatiana
Ziolli, Roberta L.
Siciliano, Salvatore
author_role author
author2 Figueiredo, Livia
Lemos, Leila
Moura, Jailson Fulgêncio de
Rocha, Rafael C. C.
Saint Pierre, Tatiana
Ziolli, Roberta L.
Siciliano, Salvatore
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Hauser-Davis, Rachel Ann
Figueiredo, Livia
Lemos, Leila
Moura, Jailson Fulgêncio de
Rocha, Rafael C. C.
Saint Pierre, Tatiana
Ziolli, Roberta L.
Siciliano, Salvatore
dc.subject.other.pt_BR.fl_str_mv Fracionamento metálico subcelular
Desintoxicação metálica
Biodisponibilidade
Contaminação
topic Fracionamento metálico subcelular
Desintoxicação metálica
Biodisponibilidade
Contaminação
Odontocetes
Subcellular metal fractionation
Metal detoxification
Bioavailability
Contamination
dc.subject.en.pt_BR.fl_str_mv Odontocetes
Subcellular metal fractionation
Metal detoxification
Bioavailability
Contamination
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Avaliação e Promoção da Saúde Ambiental. Rio de Janeiro, RJ, Brasil / GEMM-Lagos. Araruama, RJ, Brasil.
publishDate 2020
dc.date.issued.fl_str_mv 2020
dc.date.accessioned.fl_str_mv 2021-01-25T15:10:23Z
dc.date.available.fl_str_mv 2021-01-25T15:10:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv HAUSER-DAVIS, Rachel Ann et al. Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil. Frontiers in Marine Science, v. 7, Article 584195, p. 1-8, Dec. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/45802
dc.identifier.issn.pt_BR.fl_str_mv 2296-7745
dc.identifier.doi.none.fl_str_mv 10.3389/fmars.2020.584195
identifier_str_mv HAUSER-DAVIS, Rachel Ann et al. Subcellular Cadmium, Lead and Mercury Compartmentalization in Guiana Dolphins (Sotalia guianensis) From Southeastern Brazil. Frontiers in Marine Science, v. 7, Article 584195, p. 1-8, Dec. 2020.
2296-7745
10.3389/fmars.2020.584195
url https://www.arca.fiocruz.br/handle/icict/45802
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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