The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/15331 |
Resumo: | Universidade de São Paulo. Instituto de Química. Departamento de Bioquímica. São Paulo, SP, Brasil |
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Zingales, Bianca SilvanaMiles, Michael ACampbell, David ATibayrenc, MichelMacedo, Andrea MaraTeixeira, Marta Maria GeraldesSchijman, Alejandro GLlewellyn, Martin SSilva, Eliane LagesMachado, Carlos RenatoAndrade, Sonia GumesSturm, Nancy R2016-08-23T12:55:42Z2016-08-23T12:55:42Z2012ZINGALES, B. S. et al. The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infection, Genetics and Evolution, v. 12, p. 240–253, 2012.1567-1348https://www.arca.fiocruz.br/handle/icict/1533110.1016/j.meegid.2011.12.009engElsevierEstirpes de Trypanosoma cruziUnidade de digitação discretaGenotipagemFilogeografiaHibridizaçãoPatologiaTrypanosoma cruzi strainsGenotypingPhylogeographyHybridizationPathologyThe revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applicationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de São Paulo. Instituto de Química. Departamento de Bioquímica. São Paulo, SP, BrasilThe London School of Hygiene and Tropical Medicine. London, UKUniversity of California at Los Angeles. David Geffen School of Medicine. Department of Microbiology, Immunology & Molecular Genetics. Los Angeles, USAMaladies Infectieuses et Vecteurs Ecologie, Génétique, Evolution et Contrôle. Paris, FranceUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Bioquímica e Imunologia. Belo Horizonte, MG, BrasilUniversidade de São Paulo. Instituto de Biociências. Departamento de Parasitologia. São Paulo, SP, BrasilInstituto de Investigaciones en Ingeniería Genética y Biología Molecular “Dr. Héctor N. Torres”. Laboratorio de Biología Molecular de la Enfermedad de Chagas. Buenos Aires, ArgentinaThe London School of Hygiene and Tropical Medicine. London, UKUniversidade Federal do Triângulo Mineiro. Departamento de Ciências Biológicas. Uberaba, MG, BrasilUniversidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Bioquímica e Imunologia. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversity of California at Los Angeles. David Geffen School of Medicine. Department of Microbiology, Immunology & Molecular Genetics. Los Angeles, USAThe protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in nature for millions of years. The human infection, named Chagas disease, is a major public health problem for Latin America. T. cruzi is genetically highly diverse and the understanding of the population structure of this parasite is critical because of the links to transmission cycles and disease. At present, T. cruzi is partitioned into six discrete typing units (DTUs), TcI-TcVI. Here we focus on the current status of taxonomy-related areas such as population structure, phylogeographical and eco-epidemiological features, and the correlation of DTU with natural and experimental infection. We also summarize methods for DTU genotyping, available for widespread use in endemic areas. For the immediate future multilocus sequence typing is likely to be the gold standard for population studies. We conclude that greater advances in our knowledge on pathogenic and epidemiological features of these parasites are expected in the coming decade through the comparative analysis of the genomes from isolates of various DTUs.Discrete typing unitinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15331/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALZingales B The revised....pdfZingales B The revised....pdfapplication/pdf805329https://www.arca.fiocruz.br/bitstream/icict/15331/2/Zingales%20B%20The%20revised....pdf57f2ef2b293f4c844093bb34ea5cc263MD52TEXTZingales B The revised....pdf.txtZingales B The revised....pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| title |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| spellingShingle |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications Zingales, Bianca Silvana Estirpes de Trypanosoma cruzi Unidade de digitação discreta Genotipagem Filogeografia Hibridização Patologia Trypanosoma cruzi strains Genotyping Phylogeography Hybridization Pathology |
| title_short |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| title_full |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| title_fullStr |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| title_full_unstemmed |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| title_sort |
The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications |
| author |
Zingales, Bianca Silvana |
| author_facet |
Zingales, Bianca Silvana Miles, Michael A Campbell, David A Tibayrenc, Michel Macedo, Andrea Mara Teixeira, Marta Maria Geraldes Schijman, Alejandro G Llewellyn, Martin S Silva, Eliane Lages Machado, Carlos Renato Andrade, Sonia Gumes Sturm, Nancy R |
| author_role |
author |
| author2 |
Miles, Michael A Campbell, David A Tibayrenc, Michel Macedo, Andrea Mara Teixeira, Marta Maria Geraldes Schijman, Alejandro G Llewellyn, Martin S Silva, Eliane Lages Machado, Carlos Renato Andrade, Sonia Gumes Sturm, Nancy R |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Zingales, Bianca Silvana Miles, Michael A Campbell, David A Tibayrenc, Michel Macedo, Andrea Mara Teixeira, Marta Maria Geraldes Schijman, Alejandro G Llewellyn, Martin S Silva, Eliane Lages Machado, Carlos Renato Andrade, Sonia Gumes Sturm, Nancy R |
| dc.subject.other.none.fl_str_mv |
Estirpes de Trypanosoma cruzi Unidade de digitação discreta Genotipagem Filogeografia Hibridização Patologia |
| topic |
Estirpes de Trypanosoma cruzi Unidade de digitação discreta Genotipagem Filogeografia Hibridização Patologia Trypanosoma cruzi strains Genotyping Phylogeography Hybridization Pathology |
| dc.subject.en.none.fl_str_mv |
Trypanosoma cruzi strains Genotyping Phylogeography Hybridization Pathology |
| description |
Universidade de São Paulo. Instituto de Química. Departamento de Bioquímica. São Paulo, SP, Brasil |
| publishDate |
2012 |
| dc.date.issued.fl_str_mv |
2012 |
| dc.date.accessioned.fl_str_mv |
2016-08-23T12:55:42Z |
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2016-08-23T12:55:42Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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| dc.identifier.citation.fl_str_mv |
ZINGALES, B. S. et al. The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infection, Genetics and Evolution, v. 12, p. 240–253, 2012. |
| dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/15331 |
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1567-1348 |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.meegid.2011.12.009 |
| identifier_str_mv |
ZINGALES, B. S. et al. The revised Trypanosoma cruzi subspecific nomenclature: rationale, epidemiological relevance and research applications. Infection, Genetics and Evolution, v. 12, p. 240–253, 2012. 1567-1348 10.1016/j.meegid.2011.12.009 |
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Elsevier |
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Elsevier |
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