Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/31179 |
Resumo: | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil. |
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Pimentel, Maria Inês FernandesVasconcellos, Érica de Camargo Ferreira E.Ribeiro, Carla de OliveiraLyra, Marcelo RosandiskiSaheki, Mauricio NaotoSalgueiro, Mariza de MatosAntonio, Liliane de FátimaSchubach, Armando de Oliveira2019-01-21T14:01:37Z2019-01-21T14:01:37Z2017PIMENTEL, Maria Inês Fernandes et al. Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 2, p. 269-272, Mar./Apr. 2017.0037-8682https://www.arca.fiocruz.br/handle/icict/3117910.1590/0037-8682-0323-20161678-9849engSociedade Brasileira de Medicina TropicalIntralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbiditiesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Técnico-Educacional Souza Marques. Escola de Medicina. Rio de Janeiro, RJ, Brasil.Instituto Nacional do Câncer. Centro de Medula Óssea. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Although New World cutaneous leishmaniasis is not itself a life-threatening disease, its treatment with systemic antimonials can cause toxicity that can be dangerous to some patients. Intralesional meglumine antimoniate provides a viable, less toxic alternative. Herein, we describe an alternative treatment with subcutaneous intralesional injections of meglumine antimoniate into large periarticular lesions of three patients with cutaneous leishmaniasis and comorbidities. This treatment was safe, successful, and well tolerated. This case series suggests that intralesional meglumine antimoniate is an effective therapy for cutaneous leishmaniasis, even with periarticular lesions. This hypothesis should be tested in controlled clinical trials.Cutaneous leishmaniasisMeglumine antimoniateIntralesional injectionsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31179/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Pimentel_Maria_Inês_etal_INI_2017.pdfve_Pimentel_Maria_Inês_etal_INI_2017.pdfapplication/pdf2173730https://www.arca.fiocruz.br/bitstream/icict/31179/2/ve_Pimentel_Maria_In%c3%aas_etal_INI_2017.pdf3fbc041a08e2aa9d7750e34dd98f740eMD52TEXTve_Pimentel_Maria_Inês_etal_INI_2017.pdf.txtve_Pimentel_Maria_Inês_etal_INI_2017.pdf.txtExtracted texttext/plain12737https://www.arca.fiocruz.br/bitstream/icict/31179/3/ve_Pimentel_Maria_In%c3%aas_etal_INI_2017.pdf.txta71eb5a45fed194ac1b13b705fec8dc5MD53icict/311792019-01-22 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| dc.title.pt_BR.fl_str_mv |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| title |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| spellingShingle |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities Pimentel, Maria Inês Fernandes Cutaneous leishmaniasis Meglumine antimoniate Intralesional injections |
| title_short |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| title_full |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| title_fullStr |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| title_full_unstemmed |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| title_sort |
Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities |
| author |
Pimentel, Maria Inês Fernandes |
| author_facet |
Pimentel, Maria Inês Fernandes Vasconcellos, Érica de Camargo Ferreira E. Ribeiro, Carla de Oliveira Lyra, Marcelo Rosandiski Saheki, Mauricio Naoto Salgueiro, Mariza de Matos Antonio, Liliane de Fátima Schubach, Armando de Oliveira |
| author_role |
author |
| author2 |
Vasconcellos, Érica de Camargo Ferreira E. Ribeiro, Carla de Oliveira Lyra, Marcelo Rosandiski Saheki, Mauricio Naoto Salgueiro, Mariza de Matos Antonio, Liliane de Fátima Schubach, Armando de Oliveira |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pimentel, Maria Inês Fernandes Vasconcellos, Érica de Camargo Ferreira E. Ribeiro, Carla de Oliveira Lyra, Marcelo Rosandiski Saheki, Mauricio Naoto Salgueiro, Mariza de Matos Antonio, Liliane de Fátima Schubach, Armando de Oliveira |
| dc.subject.en.pt_BR.fl_str_mv |
Cutaneous leishmaniasis Meglumine antimoniate Intralesional injections |
| topic |
Cutaneous leishmaniasis Meglumine antimoniate Intralesional injections |
| description |
Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil. |
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2017 |
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2017 |
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2019-01-21T14:01:37Z |
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2019-01-21T14:01:37Z |
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PIMENTEL, Maria Inês Fernandes et al. Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 2, p. 269-272, Mar./Apr. 2017. |
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https://www.arca.fiocruz.br/handle/icict/31179 |
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0037-8682 |
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10.1590/0037-8682-0323-2016 |
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1678-9849 |
| identifier_str_mv |
PIMENTEL, Maria Inês Fernandes et al. Intralesional treatment with meglumine antimoniate in three patients with New World cutaneous leishmaniasis and large periarticular lesions with comorbidities. Revista da Sociedade Brasileira de Medicina Tropical, v. 50, n. 2, p. 269-272, Mar./Apr. 2017. 0037-8682 10.1590/0037-8682-0323-2016 1678-9849 |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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