Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis

Detalhes bibliográficos
Autor(a) principal: Miranda, Luciana de Freitas Campos
Data de Publicação: 2019
Outros Autores: Pacheco, Raquel da Silva, Pimentel, Maria Inês Fernandes, Salgueiro, Mariza de Matos, Silva, Aline Fagundes da, Mello, Cíntia Xavier de, Barros, Juliana Helena da Silva, Valete-Rosalino, Claudia Maria, Madeira, Maria de Fátima, Xavier, Samanta Cristina das Chagas, Schubach, Armando de Oliveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/37637
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.
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spelling Miranda, Luciana de Freitas CamposPacheco, Raquel da SilvaPimentel, Maria Inês FernandesSalgueiro, Mariza de MatosSilva, Aline Fagundes daMello, Cíntia Xavier deBarros, Juliana Helena da SilvaValete-Rosalino, Claudia MariaMadeira, Maria de FátimaXavier, Samanta Cristina das ChagasSchubach, Armando de Oliveira2019-12-05T13:43:10Z2019-12-05T13:43:10Z2019MIRANDA, Luciana de Freitas Campos et al. Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: Species typing and flow of travelers and migrants with leishmaniasis. Plos Neglected Tropical Diseases, p. 1-20, Nov. 2019.1935-2727https://www.arca.fiocruz.br/handle/icict/3763710.1371/journal.pntd.00077481935-2735engPublic Library of ScienceGeospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.Background: We identified the species of Leishmania isolated from traveling and migrant patients attended in a reference center from 2000 to 2015, we performed the georeferencing of these species in Rio de Janeiro (RJ) state and we had knowledge about the human flows between the likely location of infection (LLI) and place of residence (PR) in RJ state, Brazil. Methodology/Principal findings: This is a retrospective cross-sectional study including 171 patients diagnosed with ATL. Google Maps, OpenStreetMap, and Bing Maps were tools used to georeference LLI and PR. For etiological identification, we used isoenzyme electrophoresis, polymerase chain reaction-restriction fragment length polymorphism (molecular target hsp70C with restriction enzymes HaeIII and BstUI), and sequencing of the internal transcribed spacer of ribosomal DNA. ARCGIS software was used to create maps of the geographic distribution of Leishmania species in the state and municipality of RJ, together with flows between the LLI and PR. Isolates from 104 patients were identified as: L. (Viannia) braziliensis (80.8%), L. (V.) naiffi (7.7%), L. (V.) guyanensis (6.7%), L. (Leishmania) amazonensis (1%), and genetic variants of L. (V.) braziliensis (3.8%). The flow maps showed that the LLI included 4 countries, 19 Brazilian states, and 18 municipalities of RJ state. The Brazilian states with the highest density of cases were Amazonas (n = 32), Bahia (n = 18), and Ceará (n = 15). Conclusions/Significance: This work is the first contribution to the knowledge of the routes of Leishmania species introduced in RJ state by migrants and travelers patients. L. (V.) braziliensis, L. (V.) guyanensis, L. (V.) naiffi, L. (L.) amazonensis, and genetic variants of L. (V.) braziliensis were identified in RJ state. To determine whether the autochthonous transmission of these imported species is possible it is necessary the adaptation of these species to environmental conditions as well as the presence of reservoirs and phlebotomine vectors in this region.Tegumentary leishmaniasisGeospatial analysisRio de JaneiroBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83104https://www.arca.fiocruz.br/bitstream/icict/37637/1/license.txt79178e5f2a0eb066867a274556814938MD51ORIGINALve_Miranda_Luciana_etal_INI_2019.pdfve_Miranda_Luciana_etal_INI_2019.pdfapplication/pdf3522154https://www.arca.fiocruz.br/bitstream/icict/37637/2/ve_Miranda_Luciana_etal_INI_2019.pdf9b01d25f62087a8bfe0f1dd19f0087f0MD52TEXTve_Miranda_Luciana_etal_INI_2019.pdf.txtve_Miranda_Luciana_etal_INI_2019.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
title Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
spellingShingle Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
Miranda, Luciana de Freitas Campos
Tegumentary leishmaniasis
Geospatial analysis
Rio de Janeiro
Brazil
title_short Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
title_full Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
title_fullStr Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
title_full_unstemmed Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
title_sort Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: species typing and flow of travelers and migrants with leishmaniasis
author Miranda, Luciana de Freitas Campos
author_facet Miranda, Luciana de Freitas Campos
Pacheco, Raquel da Silva
Pimentel, Maria Inês Fernandes
Salgueiro, Mariza de Matos
Silva, Aline Fagundes da
Mello, Cíntia Xavier de
Barros, Juliana Helena da Silva
Valete-Rosalino, Claudia Maria
Madeira, Maria de Fátima
Xavier, Samanta Cristina das Chagas
Schubach, Armando de Oliveira
author_role author
author2 Pacheco, Raquel da Silva
Pimentel, Maria Inês Fernandes
Salgueiro, Mariza de Matos
Silva, Aline Fagundes da
Mello, Cíntia Xavier de
Barros, Juliana Helena da Silva
Valete-Rosalino, Claudia Maria
Madeira, Maria de Fátima
Xavier, Samanta Cristina das Chagas
Schubach, Armando de Oliveira
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Miranda, Luciana de Freitas Campos
Pacheco, Raquel da Silva
Pimentel, Maria Inês Fernandes
Salgueiro, Mariza de Matos
Silva, Aline Fagundes da
Mello, Cíntia Xavier de
Barros, Juliana Helena da Silva
Valete-Rosalino, Claudia Maria
Madeira, Maria de Fátima
Xavier, Samanta Cristina das Chagas
Schubach, Armando de Oliveira
dc.subject.en.pt_BR.fl_str_mv Tegumentary leishmaniasis
Geospatial analysis
Rio de Janeiro
Brazil
topic Tegumentary leishmaniasis
Geospatial analysis
Rio de Janeiro
Brazil
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica e Vigilância em Leishmanioses. Rio de Janeiro, RJ, Brasil.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-12-05T13:43:10Z
dc.date.available.fl_str_mv 2019-12-05T13:43:10Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MIRANDA, Luciana de Freitas Campos et al. Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: Species typing and flow of travelers and migrants with leishmaniasis. Plos Neglected Tropical Diseases, p. 1-20, Nov. 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/37637
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0007748
dc.identifier.eissn.none.fl_str_mv 1935-2735
identifier_str_mv MIRANDA, Luciana de Freitas Campos et al. Geospatial analysis of tegumentary leishmaniasis in Rio de Janeiro state, Brazil from 2000 to 2015: Species typing and flow of travelers and migrants with leishmaniasis. Plos Neglected Tropical Diseases, p. 1-20, Nov. 2019.
1935-2727
10.1371/journal.pntd.0007748
1935-2735
url https://www.arca.fiocruz.br/handle/icict/37637
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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