Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile

Detalhes bibliográficos
Autor(a) principal: Schitini Junior, Osvaldo Schitini
Data de Publicação: 2019
Outros Autores: Henriques, Águida Cristina Gomes, Freitas, Valéria Souza, Gurgel, Clarissa Araújo, Cury, Patrícia Ramos, Souza, Lélia Batista, Santos, Eliabe Almeida dos, Azevedo, Roberto Almeida de, Silva, Viviane Palmeira da, Santos, Jean Nunes dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/34170
Resumo: Clarissa Araújo Gurgel. Fundação Oswaldo Cruz. Instituto Gonçalo Muniz. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
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spelling Schitini Junior, Osvaldo SchitiniHenriques, Águida Cristina GomesFreitas, Valéria SouzaGurgel, Clarissa AraújoCury, Patrícia RamosSouza, Lélia BatistaSantos, Eliabe Almeida dosAzevedo, Roberto Almeida deSilva, Viviane Palmeira daSantos, Jean Nunes dos2019-07-16T18:14:53Z2019-07-16T18:14:53Z2019SCHITINI JUNIOR, Osvaldo Schitini et al. Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile. Journal of Oral Diagnosis, p. 1-7, 2019.2525-5711https://www.arca.fiocruz.br/handle/icict/3417010.5935/2525-5711.20180025Clarissa Araújo Gurgel. Fundação Oswaldo Cruz. Instituto Gonçalo Muniz. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.CNPQ (Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil) and CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil).Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Estadual de Feira de Santana. Dental School. Department of Propaedeutic and Integrated Clinic. Feira de Santana, BA, Brazil.Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Federal do Rio Grande do Norte. Dental School. Department of Oral Pathology. Natal, RN,Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Universidade Federal da Bahia. Dental School. Department of Propaedeutic and Integrated Clinic. Salvador, BA, Brazil.Introduction: The mechanisms of cell differentiation and pathogenesis in oral epidermoid cysts and dermoid cyst is poorly know. Objective: To report clinicopathological features and investigate cytokeratin profile of oral epidermoid cysts and dermoid cyst. Material and Methods: Eight cases of epidermoid cysts, 4 of dermoid cyst, and 2 Fordyce granules were included. For analysis of the immunohistochemical expression of cytokeratins (6, 7, 8, 10, 13, 14, 18 and 19), brown staining in the sections examined were defined as positive considering three layers: superficial, intermediate and basal. Results: In dermoid cyst, cytokeratins 7, 8, 9 and 19 were expressed in one case. Cytokeratin 6 was detected in six cases of epidermoid cysts. Cytokeratins 10, 13 and 14 were expressed in all cysts. Cytokeratin 18 was absent in all cysts. Cytokeratins 10 and 14 was observed in Fordyce granules. Cytokeratin 10 was more expressed in peripheral cells and immature sebaceous glands. As these glands became more differentiated, cytokeratin 10 was not detected, while cytokeratin 14 was expressed in mature sebocytes. Cytokeratins 10, 13 and 14 were expressed in the lining mucosa adjacent to Fordyce granules, similar to normal oral mucosal lining. Conclusion: cytokeratin profile is altered in dermoid cyst and epidermoid cysts compared to lining oral mucosa.engSociedade Brasileira de Estomatologia e Patologia OralCisto dermoideCisto EpidérmicoQueratinaDermoid CystEpidermal CystKeratinsDermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profileinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/34170/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALSchitini Junior, O. Dermoid epidermoid....2019.pdfSchitini Junior, O. Dermoid epidermoid....2019.pdfapplication/pdf1443984https://www.arca.fiocruz.br/bitstream/icict/34170/2/Schitini%20Junior%2c%20O.%20Dermoid%20epidermoid....2019.pdfd456f68b174c2860d92b0ad1137893aaMD52TEXTSchitini Junior, O. Dermoid epidermoid....2019.pdf.txtSchitini Junior, O. 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dc.title.pt_BR.fl_str_mv Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
title Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
spellingShingle Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
Schitini Junior, Osvaldo Schitini
Cisto dermoide
Cisto Epidérmico
Queratina
Dermoid Cyst
Epidermal Cyst
Keratins
title_short Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
title_full Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
title_fullStr Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
title_full_unstemmed Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
title_sort Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile
author Schitini Junior, Osvaldo Schitini
author_facet Schitini Junior, Osvaldo Schitini
Henriques, Águida Cristina Gomes
Freitas, Valéria Souza
Gurgel, Clarissa Araújo
Cury, Patrícia Ramos
Souza, Lélia Batista
Santos, Eliabe Almeida dos
Azevedo, Roberto Almeida de
Silva, Viviane Palmeira da
Santos, Jean Nunes dos
author_role author
author2 Henriques, Águida Cristina Gomes
Freitas, Valéria Souza
Gurgel, Clarissa Araújo
Cury, Patrícia Ramos
Souza, Lélia Batista
Santos, Eliabe Almeida dos
Azevedo, Roberto Almeida de
Silva, Viviane Palmeira da
Santos, Jean Nunes dos
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Schitini Junior, Osvaldo Schitini
Henriques, Águida Cristina Gomes
Freitas, Valéria Souza
Gurgel, Clarissa Araújo
Cury, Patrícia Ramos
Souza, Lélia Batista
Santos, Eliabe Almeida dos
Azevedo, Roberto Almeida de
Silva, Viviane Palmeira da
Santos, Jean Nunes dos
dc.subject.other.pt_BR.fl_str_mv Cisto dermoide
Cisto Epidérmico
Queratina
topic Cisto dermoide
Cisto Epidérmico
Queratina
Dermoid Cyst
Epidermal Cyst
Keratins
dc.subject.en.pt_BR.fl_str_mv Dermoid Cyst
Epidermal Cyst
Keratins
description Clarissa Araújo Gurgel. Fundação Oswaldo Cruz. Instituto Gonçalo Muniz. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-07-16T18:14:53Z
dc.date.available.fl_str_mv 2019-07-16T18:14:53Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SCHITINI JUNIOR, Osvaldo Schitini et al. Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile. Journal of Oral Diagnosis, p. 1-7, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/34170
dc.identifier.issn.pt_BR.fl_str_mv 2525-5711
dc.identifier.doi.pt_BR.fl_str_mv 10.5935/2525-5711.20180025
identifier_str_mv SCHITINI JUNIOR, Osvaldo Schitini et al. Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile. Journal of Oral Diagnosis, p. 1-7, 2019.
2525-5711
10.5935/2525-5711.20180025
url https://www.arca.fiocruz.br/handle/icict/34170
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Estomatologia e Patologia Oral
publisher.none.fl_str_mv Sociedade Brasileira de Estomatologia e Patologia Oral
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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