Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.3390/pathogens10060736 |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/48461 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil. |
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Dario, Maria AugustaPavan, Márcio GalvãoRodrigues, Marina SilvaLisboa, Cristiane VarellaKluyber, DarioDesbiez, Arnaud L. J.Herrera, Heitor MiragliaRoque, André Luiz RodriguesLima, LucianaTeixeira, Marta M. G.Jansen, Ana Maria2021-08-01T18:29:47Z2021-08-01T18:29:47Z2021DARIO, Maria Augusta et al. Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes. Pathogens, v. 10, n.736, 18 p, June 2021.2076-0817https://www.arca.fiocruz.br/handle/icict/4846110.3390/pathogens10060736engMDPITrypanosoma rangeliMamíferosEcologia de parasitasLinhagensBiomas brasileirosTrypanosoma rangeliMammalsParasite ecologyLineagesBrazilian biomesTrypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Mosquitos Transmissores de Hematozoários. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Associate Researcher, Naples Zoo at Caribbeans Gardens. Naples, FL, USA / Instituto de Conservação de Animais Silvestres (ICAS). Campo Grande, MS, Brasil.Instituto de Conservação de Animais Silvestres (ICAS). Campo Grande, MS, Brasil.Universidade Católica Dom Bosco. Pós-Graduação em Ciência Ambientais e Sustentabilidade Agropecuária. Campo Grande, MS, Brasil / Universidade Federal de Mato Grosso do Sul. Pós-Graduação em Ecologia e Conservação. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. São Paulo, SP, Brasil.Universidade de São Paulo. Instituto de Ciências Biomédicas. Departamento de Parasitologia. São Paulo, SP, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil.Abstract: Trypanosoma rangeli is a generalist hemoflagellate that infects mammals and is transmitted by triatomines around Latin America. Due to its high genetic diversity, it can be classified into two to five lineages. In Brazil, its distribution outside the Amazon region is virtually unknown, and knowledge on the ecology of its lineages and on host species diversity requires further investigation. Here, we analyzed 57 T. rangeli samples obtained from hemocultures and blood clots of 1392 mammals captured in different Brazilian biomes. The samples were subjected to small subunit (SSU) rDNA amplification and sequencing to confirm T. rangeli infection. Phylogenetic inferences and haplotype networks were reconstructed to classify T. rangeli lineages and to infer the genetic diversity of the samples. The results obtained in our study highlighted both the mammalian host range and distribution of T. rangeli in Brazil: infection was observed in five new species (Procyon cancrivorous, Priodontes maximum, Alouatta belzebul, Sapajus libidinosus, and Trinomys dimidiatus), and transmission was observed in the Caatinga biome. The coati (Nasua nasua) and capuchin monkey (S. libidinosus) are the key hosts of T. rangeli. We identified all four T. rangeli lineages previously reported in Brazil (A, B, D, and E) and possibly two new genotypes.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48461/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMariaAugustaDario_MarcioPavan_etal_IOC_2021.pdfMariaAugustaDario_MarcioPavan_etal_IOC_2021.pdfapplication/pdf4989598https://www.arca.fiocruz.br/bitstream/icict/48461/2/MariaAugustaDario_MarcioPavan_etal_IOC_2021.pdf38bcc16f2c02f8a64e0e3c40cd4c2598MD52TEXTMariaAugustaDario_MarcioPavan_etal_IOC_2021.pdf.txtMariaAugustaDario_MarcioPavan_etal_IOC_2021.pdf.txtExtracted texttext/plain71324https://www.arca.fiocruz.br/bitstream/icict/48461/3/MariaAugustaDario_MarcioPavan_etal_IOC_2021.pdf.txtea8fc8e55568a5d25f7d0004bc665e7aMD53icict/484612021-08-02 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| dc.title.pt_BR.fl_str_mv |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| title |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| spellingShingle |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes Dario, Maria Augusta Trypanosoma rangeli Mamíferos Ecologia de parasitas Linhagens Biomas brasileiros Trypanosoma rangeli Mammals Parasite ecology Lineages Brazilian biomes |
| title_short |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| title_full |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| title_fullStr |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| title_full_unstemmed |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| title_sort |
Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes |
| author |
Dario, Maria Augusta |
| author_facet |
Dario, Maria Augusta Pavan, Márcio Galvão Rodrigues, Marina Silva Lisboa, Cristiane Varella Kluyber, Dario Desbiez, Arnaud L. J. Herrera, Heitor Miraglia Roque, André Luiz Rodrigues Lima, Luciana Teixeira, Marta M. G. Jansen, Ana Maria |
| author_role |
author |
| author2 |
Pavan, Márcio Galvão Rodrigues, Marina Silva Lisboa, Cristiane Varella Kluyber, Dario Desbiez, Arnaud L. J. Herrera, Heitor Miraglia Roque, André Luiz Rodrigues Lima, Luciana Teixeira, Marta M. G. Jansen, Ana Maria |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Dario, Maria Augusta Pavan, Márcio Galvão Rodrigues, Marina Silva Lisboa, Cristiane Varella Kluyber, Dario Desbiez, Arnaud L. J. Herrera, Heitor Miraglia Roque, André Luiz Rodrigues Lima, Luciana Teixeira, Marta M. G. Jansen, Ana Maria |
| dc.subject.other.pt_BR.fl_str_mv |
Trypanosoma rangeli Mamíferos Ecologia de parasitas Linhagens Biomas brasileiros |
| topic |
Trypanosoma rangeli Mamíferos Ecologia de parasitas Linhagens Biomas brasileiros Trypanosoma rangeli Mammals Parasite ecology Lineages Brazilian biomes |
| dc.subject.en.pt_BR.fl_str_mv |
Trypanosoma rangeli Mammals Parasite ecology Lineages Brazilian biomes |
| description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia de Tripanosomatídeos. Rio de Janeiro, RJ, Brasil. |
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2021 |
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2021-08-01T18:29:47Z |
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2021-08-01T18:29:47Z |
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2021 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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DARIO, Maria Augusta et al. Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes. Pathogens, v. 10, n.736, 18 p, June 2021. |
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https://www.arca.fiocruz.br/handle/icict/48461 |
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2076-0817 |
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10.3390/pathogens10060736 |
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DARIO, Maria Augusta et al. Trypanosoma rangeli Genetic, Mammalian Hosts, and Geographical Diversity from Five Brazilian Biomes. Pathogens, v. 10, n.736, 18 p, June 2021. 2076-0817 10.3390/pathogens10060736 |
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