A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome

Detalhes bibliográficos
Autor(a) principal: Mathias, Rasika Ann
Data de Publicação: 2016
Outros Autores: Taub, Margaret A, Gignoux, Christopher R, Fu, Wenqing, Musharoff, Shaila, O'Connor, Timothy D, Vergara, Candelaria, Torgerson, Dara G, Pino-Yanes, Maria, Shringarpure, Suyash S, Huang, Lili, Rafaels, Nicholas, Boorgula, Meher Preethi, Johnston, Henry Richard, Ortega, Victor E, Levin, Albert M, Song, Wei, Torres, Raul, Padhukasahasram, Badri, Eng, Celeste, Mejia-Mejia, Delmy-Aracely, Ferguson, Trevor, Qin, Zhaohui S, Scott, Alan F, Yazdanbakhsh, Maria, Wilson, James G, Marrugo, Javier, Lange, Leslie A, Kumar, Rajesh, Avila, Pedro C, Williams, L Keoki, Watson, Harold, Ware, Lorraine B, Olopade, Christopher, Olopade, Olufunmilayo, Oliveira, Ricardo Riccio, Ober, Carole, Nicolae, Dan L, Meyers, Deborah, Mayorga, Alvaro, Knight-Madden, Jennifer, Hartert, Tina, Hansel, Nadia N, Foreman, Marilyn G, Ford, Jean G, Faruque, Mezbah U, Dunston, Georgia M, Caraballo, Luis, Burchard, Esteban G, Bleecker, Eugene, Araujo, Maria Ilma Andrade Santos, Herrera-Paz, Edwin Francisco, Gietzen, Kimberly, Grus, Wendy E, Bamshad, Michael, Bustamante, Carlos D, Kenny, Eimear E, Hernandez, Ryan D, Beaty, Terri H, Ruczinski, Ingo, Akey, Joshua, Barnes, Kathleen C
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/18176
Resumo: Ricardo Riccio Oliveira. Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil, 1 Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21224, USA. 2 Department of Epidemiology, Bloomberg School of Public Health, JHU, Baltimore, Maryland 21205, USA. 3 Department of Biostatistics, Bloomberg School of Public Health, JHU, Baltimore, Maryland 21205, USA. 4 Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA. 5 Department of Genomic Sciences, University of Washington, Seattle, Washington 98195, USA. 6 Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 7 Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 8 Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 9 Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA. 10 CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid 28029, Spain. 11 Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia 30322, USA. 12 Center for Human Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA. 13 Department of Public Health Sciences, Henry Ford Health System, Detroit, Michigan 48202, USA. 14 Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, California 94158, USA. 15 Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA. 16 Centro de Neumologia y Alergias, San Pedro Sula 21102, Honduras. 17 Faculty of Medicine, Centro Medico de la Familia, San Pedro Sula 21102, Honduras. 18 Tropical Medicine Research Institute, The University of the West Indies, St. Michael BB11115, Barbados. 19 Department of Parasitology, Leiden University Medical Center, Leiden 2333ZA, The Netherlands. 20 Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. 21 Instituto de Investigaciones Immunologicas, Universidad de Cartagena, Cartagena 130000, Colombia. 22 Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA. 23 Department of Pediatrics, Northwestern University, Chicago, Illinois 60637, USA. 24 The Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, Illinois 60637, USA. 25 Department of Medicine, Northwestern University, Chicago, Illinois 60637, USA. 26 Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA. 27 Faculty of Medical Sciences Cave Hill Campus, The University of the West Indies, Bridgetown BB11000, Barbados. 28 Queen Elizabeth Hospital, The University of the West Indies, St. Michael BB11115, Barbados. 29 Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA. 30 Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee 37232, USA. 31 Department of Medicine and Center for Global Health, University of Chicago, Chicago, Illinois 60637, USA. 32 Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA. 33 Laborato´rio de Patologia Experimental, Centro de Pesquisas Gonc¸alo Moniz, Salvador 40296-710, Brazil. 34 Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA. 35 Department of Statistics, University of Chicago, Chicago, Illinois 60637, USA. 36 Pulmonary and Critical Care Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA. 37 Department of Medicine, The Brooklyn Hospital Center, Brooklyn, New York 11201, USA. 38 National Human Genome Center, Howard University College of Medicine,Washington DC 20059, USA. 39 Department of Microbiology, Howard University College of Medicine,Washington DC 20059, USA. 40 Institute for Immunological Research, Universidad de Cartagena, Cartagena 130000, Colombia. 41 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94158, USA. 42 Immunology Service, Universidade Federal da Bahia, Salvador 401110170, Brazil. 43 Facultad de Medicina, Universidad Catolica de Honduras, San Pedro Sula 21102, Honduras. 44 Illumina, Inc., San Diego, California 92122, USA. 45 Knome Inc., Cambridge, Massachusetts 02141, USA. 46 Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA. 47 Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA. 48 Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143, USA. 49 California Institute for Quantitative Biosciences, University of California, San Francisco, California 94143, USA.
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spelling Mathias, Rasika AnnTaub, Margaret AGignoux, Christopher RFu, WenqingMusharoff, ShailaO'Connor, Timothy DVergara, CandelariaTorgerson, Dara GPino-Yanes, MariaShringarpure, Suyash SHuang, LiliRafaels, NicholasBoorgula, Meher PreethiJohnston, Henry RichardOrtega, Victor ELevin, Albert MSong, WeiTorres, RaulPadhukasahasram, BadriEng, CelesteMejia-Mejia, Delmy-AracelyFerguson, TrevorQin, Zhaohui SScott, Alan FYazdanbakhsh, MariaWilson, James GMarrugo, JavierLange, Leslie AKumar, RajeshAvila, Pedro CWilliams, L KeokiWatson, HaroldWare, Lorraine BOlopade, ChristopherOlopade, OlufunmilayoOliveira, Ricardo RiccioOber, CaroleNicolae, Dan LMeyers, DeborahMayorga, AlvaroKnight-Madden, JenniferHartert, TinaHansel, Nadia NForeman, Marilyn GFord, Jean GFaruque, Mezbah UDunston, Georgia MCaraballo, LuisBurchard, Esteban GBleecker, EugeneAraujo, Maria Ilma Andrade SantosHerrera-Paz, Edwin FranciscoGietzen, KimberlyGrus, Wendy EBamshad, MichaelBustamante, Carlos DKenny, Eimear EHernandez, Ryan DBeaty, Terri HRuczinski, IngoAkey, JoshuaBarnes, Kathleen C2017-03-27T16:28:42Z2017-03-27T16:28:42Z2016MATHIAS, R. A. et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications, v. 7, p. 12522, 2016.2041-1723https://www.arca.fiocruz.br/handle/icict/1817610.1038/ncomms12522Ricardo Riccio Oliveira. Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil, 1 Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21224, USA. 2 Department of Epidemiology, Bloomberg School of Public Health, JHU, Baltimore, Maryland 21205, USA. 3 Department of Biostatistics, Bloomberg School of Public Health, JHU, Baltimore, Maryland 21205, USA. 4 Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA. 5 Department of Genomic Sciences, University of Washington, Seattle, Washington 98195, USA. 6 Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 7 Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 8 Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 9 Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA. 10 CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid 28029, Spain. 11 Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia 30322, USA. 12 Center for Human Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA. 13 Department of Public Health Sciences, Henry Ford Health System, Detroit, Michigan 48202, USA. 14 Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, California 94158, USA. 15 Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA. 16 Centro de Neumologia y Alergias, San Pedro Sula 21102, Honduras. 17 Faculty of Medicine, Centro Medico de la Familia, San Pedro Sula 21102, Honduras. 18 Tropical Medicine Research Institute, The University of the West Indies, St. Michael BB11115, Barbados. 19 Department of Parasitology, Leiden University Medical Center, Leiden 2333ZA, The Netherlands. 20 Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. 21 Instituto de Investigaciones Immunologicas, Universidad de Cartagena, Cartagena 130000, Colombia. 22 Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA. 23 Department of Pediatrics, Northwestern University, Chicago, Illinois 60637, USA. 24 The Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, Illinois 60637, USA. 25 Department of Medicine, Northwestern University, Chicago, Illinois 60637, USA. 26 Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA. 27 Faculty of Medical Sciences Cave Hill Campus, The University of the West Indies, Bridgetown BB11000, Barbados. 28 Queen Elizabeth Hospital, The University of the West Indies, St. Michael BB11115, Barbados. 29 Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA. 30 Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee 37232, USA. 31 Department of Medicine and Center for Global Health, University of Chicago, Chicago, Illinois 60637, USA. 32 Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA. 33 Laborato´rio de Patologia Experimental, Centro de Pesquisas Gonc¸alo Moniz, Salvador 40296-710, Brazil. 34 Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA. 35 Department of Statistics, University of Chicago, Chicago, Illinois 60637, USA. 36 Pulmonary and Critical Care Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA. 37 Department of Medicine, The Brooklyn Hospital Center, Brooklyn, New York 11201, USA. 38 National Human Genome Center, Howard University College of Medicine,Washington DC 20059, USA. 39 Department of Microbiology, Howard University College of Medicine,Washington DC 20059, USA. 40 Institute for Immunological Research, Universidad de Cartagena, Cartagena 130000, Colombia. 41 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94158, USA. 42 Immunology Service, Universidade Federal da Bahia, Salvador 401110170, Brazil. 43 Facultad de Medicina, Universidad Catolica de Honduras, San Pedro Sula 21102, Honduras. 44 Illumina, Inc., San Diego, California 92122, USA. 45 Knome Inc., Cambridge, Massachusetts 02141, USA. 46 Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA. 47 Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA. 48 Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143, USA. 49 California Institute for Quantitative Biosciences, University of California, San Francisco, California 94143, USA.Johns Hopkins University. Department of Medicine. Baltimore, Maryland, USA / Bloomberg School of Public Health JHU. Department of Epidemiology. Baltimore, Maryland, USABloomberg School of Public Health, JHU. Department of Biostatistics. Baltimore, Maryland, USAFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil. Múltipla - ver em NotasThe African Diaspora in the Western Hemisphere represents one of the largest forced migrations in history and had a profound impact on genetic diversity in modern populations. To date, the fine-scale population structure of descendants of the African Diaspora remains largely uncharacterized. Here we present genetic variation from deeply sequenced genomes of 642 individuals from North and South American, Caribbean and West African populations, substantially increasing the lexicon of human genomic variation and suggesting much variation remains to be discovered in African-admixed populations in the Americas. We summarize genetic variation in these populations, quantifying the postcolonial sex-biased European gene flow across multiple regions. Moreover, we refine estimates on the burden of deleterious variants carried across populations and how this varies with African ancestry. Our data are an important resource for empowering disease mapping studies in African-admixed individuals and will facilitate gene discovery for diseases disproportionately affecting individuals of African ancestry.engNature Publishing GroupGenética populacionalDiversidade genéticaVariação genéticaMigração humanaPopulaçãoMapeamento genéticoÁfricaGeneticsGenetic diversityGenetic variationHuman migrationPopulationGenetic mappingÁfricaA continuum of admixture in the Western Hemisphere revealed by the African Diaspora genomeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/18176/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMathias_R A continuum of...).pdfMathias_R A continuum 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dc.title.pt_BR.fl_str_mv A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
title A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
spellingShingle A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
Mathias, Rasika Ann
Genética populacional
Diversidade genética
Variação genética
Migração humana
População
Mapeamento genético
África
Genetics
Genetic diversity
Genetic variation
Human migration
Population
Genetic mapping
África
title_short A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
title_full A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
title_fullStr A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
title_full_unstemmed A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
title_sort A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome
author Mathias, Rasika Ann
author_facet Mathias, Rasika Ann
Taub, Margaret A
Gignoux, Christopher R
Fu, Wenqing
Musharoff, Shaila
O'Connor, Timothy D
Vergara, Candelaria
Torgerson, Dara G
Pino-Yanes, Maria
Shringarpure, Suyash S
Huang, Lili
Rafaels, Nicholas
Boorgula, Meher Preethi
Johnston, Henry Richard
Ortega, Victor E
Levin, Albert M
Song, Wei
Torres, Raul
Padhukasahasram, Badri
Eng, Celeste
Mejia-Mejia, Delmy-Aracely
Ferguson, Trevor
Qin, Zhaohui S
Scott, Alan F
Yazdanbakhsh, Maria
Wilson, James G
Marrugo, Javier
Lange, Leslie A
Kumar, Rajesh
Avila, Pedro C
Williams, L Keoki
Watson, Harold
Ware, Lorraine B
Olopade, Christopher
Olopade, Olufunmilayo
Oliveira, Ricardo Riccio
Ober, Carole
Nicolae, Dan L
Meyers, Deborah
Mayorga, Alvaro
Knight-Madden, Jennifer
Hartert, Tina
Hansel, Nadia N
Foreman, Marilyn G
Ford, Jean G
Faruque, Mezbah U
Dunston, Georgia M
Caraballo, Luis
Burchard, Esteban G
Bleecker, Eugene
Araujo, Maria Ilma Andrade Santos
Herrera-Paz, Edwin Francisco
Gietzen, Kimberly
Grus, Wendy E
Bamshad, Michael
Bustamante, Carlos D
Kenny, Eimear E
Hernandez, Ryan D
Beaty, Terri H
Ruczinski, Ingo
Akey, Joshua
Barnes, Kathleen C
author_role author
author2 Taub, Margaret A
Gignoux, Christopher R
Fu, Wenqing
Musharoff, Shaila
O'Connor, Timothy D
Vergara, Candelaria
Torgerson, Dara G
Pino-Yanes, Maria
Shringarpure, Suyash S
Huang, Lili
Rafaels, Nicholas
Boorgula, Meher Preethi
Johnston, Henry Richard
Ortega, Victor E
Levin, Albert M
Song, Wei
Torres, Raul
Padhukasahasram, Badri
Eng, Celeste
Mejia-Mejia, Delmy-Aracely
Ferguson, Trevor
Qin, Zhaohui S
Scott, Alan F
Yazdanbakhsh, Maria
Wilson, James G
Marrugo, Javier
Lange, Leslie A
Kumar, Rajesh
Avila, Pedro C
Williams, L Keoki
Watson, Harold
Ware, Lorraine B
Olopade, Christopher
Olopade, Olufunmilayo
Oliveira, Ricardo Riccio
Ober, Carole
Nicolae, Dan L
Meyers, Deborah
Mayorga, Alvaro
Knight-Madden, Jennifer
Hartert, Tina
Hansel, Nadia N
Foreman, Marilyn G
Ford, Jean G
Faruque, Mezbah U
Dunston, Georgia M
Caraballo, Luis
Burchard, Esteban G
Bleecker, Eugene
Araujo, Maria Ilma Andrade Santos
Herrera-Paz, Edwin Francisco
Gietzen, Kimberly
Grus, Wendy E
Bamshad, Michael
Bustamante, Carlos D
Kenny, Eimear E
Hernandez, Ryan D
Beaty, Terri H
Ruczinski, Ingo
Akey, Joshua
Barnes, Kathleen C
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dc.contributor.author.fl_str_mv Mathias, Rasika Ann
Taub, Margaret A
Gignoux, Christopher R
Fu, Wenqing
Musharoff, Shaila
O'Connor, Timothy D
Vergara, Candelaria
Torgerson, Dara G
Pino-Yanes, Maria
Shringarpure, Suyash S
Huang, Lili
Rafaels, Nicholas
Boorgula, Meher Preethi
Johnston, Henry Richard
Ortega, Victor E
Levin, Albert M
Song, Wei
Torres, Raul
Padhukasahasram, Badri
Eng, Celeste
Mejia-Mejia, Delmy-Aracely
Ferguson, Trevor
Qin, Zhaohui S
Scott, Alan F
Yazdanbakhsh, Maria
Wilson, James G
Marrugo, Javier
Lange, Leslie A
Kumar, Rajesh
Avila, Pedro C
Williams, L Keoki
Watson, Harold
Ware, Lorraine B
Olopade, Christopher
Olopade, Olufunmilayo
Oliveira, Ricardo Riccio
Ober, Carole
Nicolae, Dan L
Meyers, Deborah
Mayorga, Alvaro
Knight-Madden, Jennifer
Hartert, Tina
Hansel, Nadia N
Foreman, Marilyn G
Ford, Jean G
Faruque, Mezbah U
Dunston, Georgia M
Caraballo, Luis
Burchard, Esteban G
Bleecker, Eugene
Araujo, Maria Ilma Andrade Santos
Herrera-Paz, Edwin Francisco
Gietzen, Kimberly
Grus, Wendy E
Bamshad, Michael
Bustamante, Carlos D
Kenny, Eimear E
Hernandez, Ryan D
Beaty, Terri H
Ruczinski, Ingo
Akey, Joshua
Barnes, Kathleen C
dc.subject.other.pt_BR.fl_str_mv Genética populacional
Diversidade genética
Variação genética
Migração humana
População
Mapeamento genético
África
topic Genética populacional
Diversidade genética
Variação genética
Migração humana
População
Mapeamento genético
África
Genetics
Genetic diversity
Genetic variation
Human migration
Population
Genetic mapping
África
dc.subject.en.pt_BR.fl_str_mv Genetics
Genetic diversity
Genetic variation
Human migration
Population
Genetic mapping
África
description Ricardo Riccio Oliveira. Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, Brasil, 1 Department of Medicine, Johns Hopkins University, Baltimore, Maryland 21224, USA. 2 Department of Epidemiology, Bloomberg School of Public Health, JHU, Baltimore, Maryland 21205, USA. 3 Department of Biostatistics, Bloomberg School of Public Health, JHU, Baltimore, Maryland 21205, USA. 4 Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA. 5 Department of Genomic Sciences, University of Washington, Seattle, Washington 98195, USA. 6 Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 7 Program in Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 8 Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. 9 Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA. 10 CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid 28029, Spain. 11 Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia 30322, USA. 12 Center for Human Genomics and Personalized Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA. 13 Department of Public Health Sciences, Henry Ford Health System, Detroit, Michigan 48202, USA. 14 Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, California 94158, USA. 15 Center for Health Policy and Health Services Research, Henry Ford Health System, Detroit, Michigan 48202, USA. 16 Centro de Neumologia y Alergias, San Pedro Sula 21102, Honduras. 17 Faculty of Medicine, Centro Medico de la Familia, San Pedro Sula 21102, Honduras. 18 Tropical Medicine Research Institute, The University of the West Indies, St. Michael BB11115, Barbados. 19 Department of Parasitology, Leiden University Medical Center, Leiden 2333ZA, The Netherlands. 20 Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. 21 Instituto de Investigaciones Immunologicas, Universidad de Cartagena, Cartagena 130000, Colombia. 22 Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA. 23 Department of Pediatrics, Northwestern University, Chicago, Illinois 60637, USA. 24 The Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, Illinois 60637, USA. 25 Department of Medicine, Northwestern University, Chicago, Illinois 60637, USA. 26 Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA. 27 Faculty of Medical Sciences Cave Hill Campus, The University of the West Indies, Bridgetown BB11000, Barbados. 28 Queen Elizabeth Hospital, The University of the West Indies, St. Michael BB11115, Barbados. 29 Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA. 30 Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, Tennessee 37232, USA. 31 Department of Medicine and Center for Global Health, University of Chicago, Chicago, Illinois 60637, USA. 32 Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA. 33 Laborato´rio de Patologia Experimental, Centro de Pesquisas Gonc¸alo Moniz, Salvador 40296-710, Brazil. 34 Department of Human Genetics, University of Chicago, Chicago, Illinois 60637, USA. 35 Department of Statistics, University of Chicago, Chicago, Illinois 60637, USA. 36 Pulmonary and Critical Care Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA. 37 Department of Medicine, The Brooklyn Hospital Center, Brooklyn, New York 11201, USA. 38 National Human Genome Center, Howard University College of Medicine,Washington DC 20059, USA. 39 Department of Microbiology, Howard University College of Medicine,Washington DC 20059, USA. 40 Institute for Immunological Research, Universidad de Cartagena, Cartagena 130000, Colombia. 41 Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California 94158, USA. 42 Immunology Service, Universidade Federal da Bahia, Salvador 401110170, Brazil. 43 Facultad de Medicina, Universidad Catolica de Honduras, San Pedro Sula 21102, Honduras. 44 Illumina, Inc., San Diego, California 92122, USA. 45 Knome Inc., Cambridge, Massachusetts 02141, USA. 46 Department of Pediatrics, University of Washington, Seattle, Washington 98195, USA. 47 Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA. 48 Institute for Human Genetics, University of California, San Francisco, San Francisco, California 94143, USA. 49 California Institute for Quantitative Biosciences, University of California, San Francisco, California 94143, USA.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2017-03-27T16:28:42Z
dc.date.available.fl_str_mv 2017-03-27T16:28:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MATHIAS, R. A. et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications, v. 7, p. 12522, 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/18176
dc.identifier.issn.pt_BR.fl_str_mv 2041-1723
dc.identifier.doi.none.fl_str_mv 10.1038/ncomms12522
identifier_str_mv MATHIAS, R. A. et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications, v. 7, p. 12522, 2016.
2041-1723
10.1038/ncomms12522
url https://www.arca.fiocruz.br/handle/icict/18176
dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Nature Publishing Group
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