Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol

Detalhes bibliográficos
Autor(a) principal: Lembrança, Lucas
Data de Publicação: 2011
Outros Autores: Medina, Jéssica de Paiva, Portugal, Marcelo, Almeida, Delvone Freire Gil, Solla, Jorge Jose Santos Pereira, Gadelha, Ricardo, Freitas, Luiz Antonio Rodrigues de, Paraná, Raymundo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/15591
Resumo: Federal University of Bahia. University Hospital. Scientific Initiation Program of the Hepatology Unit. Salvador, BA, Brasil
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spelling Lembrança, LucasMedina, Jéssica de PaivaPortugal, MarceloAlmeida, Delvone Freire GilSolla, Jorge Jose Santos PereiraGadelha, RicardoFreitas, Luiz Antonio Rodrigues deParaná, Raymundo2016-09-02T13:06:26Z2016-09-02T13:06:26Z2011LEMBRANÇA, L. et al. Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol. Annals of Hepatology, v. 10, n. 1, p. 43-49, 2011.1665-268121301009https://www.arca.fiocruz.br/handle/icict/15591engEdiciones Medicina y CulturaEpidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocolinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Bahia. University Hospital. Scientific Initiation Program of the Hepatology Unit. Salvador, BA, BrasilFederal University of Bahia. University Hospital. Scientific Initiation Program of the Hepatology Unit. Salvador, BA, BrasilFederal University of Bahia. Bahia State Health Department. Salvador, BA, BrasilFederal University of Bahia. Bahia State Health Department. Salvador, BA, BrasilBahia State Health Department. Salvador, BA, BrasilMinistry of Health. National Viral Hepatitis Program. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFederal University of Bahia. Teaching Hospital. Hepatology Unit. Salvador, BA, BrasilThe main objective of this study was to describe the profile of patients who were benefitted in a collective effort to perform liver biopsies in Bahia, Brazil. METHOD: A cross-sectional study was conducted with a sample composed of all the patients who were submitted to liver biopsy during a collective effort carried out in Bahia between July 2007 and November 2009. At the time of the procedure, date on the age and gender of patients and the reason for performing the biopsy were recorded. Data on the degree of fibrosis and the presence of co-morbidities. Following statistical analysis, the frequency of the liver diseases that led to the biopsy procedure was described, and the profile of the patients was stratified into groups according to the most prevalent etiologies. RESULTS: Of the 550 patients evaluated, 55.3% were men and 44.7% women. Mean age was 46.63 ± 11.59 years and there was no statistically significant difference in age between males and females. Of the 550 patients, 72% had hepatitis C and the mean age of these patients was 48.49 ± 10.1 years, significantly higher than the mean age of the patients with hepatitis B (40.41 ± 12.43 years). Furthermore, 70.7% of the patients with hepatitis C were between 41 and 60 years of age. The most frequent fibrosis grade was F2 (44%) and the prevalence of advanced fibrosis was 27.7%. Overall, 85 patients, most of them men, had some degree of iron overload. With respect to the safety of the biopsy procedure, severe complications occurred in only two patients. CONCLUSION: Hepatitis C is the predominant liver disease that demanded liver biopsy. The profile of the patients who benefitted from this collective effort is similar to that of patients in the rest of the country. Moreover, non-Ultrasonography guided liver biopsy is safe and the collective effort to carry out liver biopsies in Bahia was found to be a viable venture.Liver biopsyHepatitisCollective effortinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/15591/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALLembrança L Epidemiological assessment....pdfLembrança L Epidemiological assessment....pdfapplication/pdf68854https://www.arca.fiocruz.br/bitstream/icict/15591/2/Lembran%c3%a7a%20L%20Epidemiological%20assessment....pdfab46220b6e2af3c2c5618b5c4ed55442MD52TEXTLembrança L Epidemiological assessment....pdf.txtLembrança L Epidemiological assessment....pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
title Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
spellingShingle Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
Lembrança, Lucas
Liver biopsy
Hepatitis
Collective effort
title_short Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
title_full Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
title_fullStr Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
title_full_unstemmed Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
title_sort Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol
author Lembrança, Lucas
author_facet Lembrança, Lucas
Medina, Jéssica de Paiva
Portugal, Marcelo
Almeida, Delvone Freire Gil
Solla, Jorge Jose Santos Pereira
Gadelha, Ricardo
Freitas, Luiz Antonio Rodrigues de
Paraná, Raymundo
author_role author
author2 Medina, Jéssica de Paiva
Portugal, Marcelo
Almeida, Delvone Freire Gil
Solla, Jorge Jose Santos Pereira
Gadelha, Ricardo
Freitas, Luiz Antonio Rodrigues de
Paraná, Raymundo
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lembrança, Lucas
Medina, Jéssica de Paiva
Portugal, Marcelo
Almeida, Delvone Freire Gil
Solla, Jorge Jose Santos Pereira
Gadelha, Ricardo
Freitas, Luiz Antonio Rodrigues de
Paraná, Raymundo
dc.subject.en.pt_BR.fl_str_mv Liver biopsy
Hepatitis
Collective effort
topic Liver biopsy
Hepatitis
Collective effort
description Federal University of Bahia. University Hospital. Scientific Initiation Program of the Hepatology Unit. Salvador, BA, Brasil
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2016-09-02T13:06:26Z
dc.date.available.fl_str_mv 2016-09-02T13:06:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LEMBRANÇA, L. et al. Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol. Annals of Hepatology, v. 10, n. 1, p. 43-49, 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/15591
dc.identifier.issn.pt_BR.fl_str_mv 1665-2681
dc.identifier.other.none.fl_str_mv 21301009
identifier_str_mv LEMBRANÇA, L. et al. Epidemiological assessment of liver disease in northeastern Brazil by means of a standardized liver biopsy protocol. Annals of Hepatology, v. 10, n. 1, p. 43-49, 2011.
1665-2681
21301009
url https://www.arca.fiocruz.br/handle/icict/15591
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Ediciones Medicina y Cultura
publisher.none.fl_str_mv Ediciones Medicina y Cultura
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/15591/1/license.txt
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