Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city

Detalhes bibliográficos
Autor(a) principal: Gonçalves, Caroline Macedo
Data de Publicação: 2014
Outros Autores: Melo, Fabrício Freire de, Bezerra, Juliana Maria Trindade, Chaves, Bárbara Aparecida, Silva, Breno M, Silva, Luciana D, Pessanha, José EM, Arias, Jorge R, Secundino, Nágila Francinete Costa, Norris, Douglas E, Pimenta, Paulo Filemon Paolucci
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/10143
Resumo: Fundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.
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spelling Gonçalves, Caroline MacedoMelo, Fabrício Freire deBezerra, Juliana Maria TrindadeChaves, Bárbara AparecidaSilva, Breno MSilva, Luciana DPessanha, José EMArias, Jorge RSecundino, Nágila Francinete CostaNorris, Douglas EPimenta, Paulo Filemon Paolucci2015-04-30T14:26:21Z2015-04-30T14:26:21Z2014GONÇALVES, Caroline Macedo et al. Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city. Parasites & Vectors, v. 7, p. 320, 20141756-3305https://www.arca.fiocruz.br/handle/icict/1014310.1186/1756-3305-7-320engBioMed CentralDistinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk cityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.Universidade Federal de Ouro Preto. Departamento de Ciências Biológicas. Ouro Preto, MG, Brazil.Universidade Federal de Minas Gerais. Departamento de Medicina Interna. Belo Horizonte, MG, BrazilPrefeitura de Belo Horizonte. Secretaria Municipal de Saude. Belo Horizonte, MG, Brazil.Retired Consultant. Manassas, Virginia, USA.Fundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.Johns Hopkins University. Bloomberg School of Public Health. Johns Hopkins Malaria Research Institute. Department of Molecular Microbiology and Immunology. Baltimore, MD, USAFundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.Background: In Brazil, dengue epidemics erupt sporadically throughout the country and it is unclear if outbreaks may initiate a sustainable transmission cycle. There are few studies evaluating the ability of Brazilian Aedes aegypti populations to transmit dengue virus (DENV). The aim of this study was to compare DENV susceptibility of field-captured Ae. aegypti populations from nine distinct geographic areas of the city of Belo Horizonte in 2009 and 2011. Infection Rate (IR), Vector Competence (VC) and Disseminated Infection Rate (DIR) were determined. Methods: Aedes aegypti eggs from each region were collected and reared separately in an insectary. Adult females were experimentally infected with DENV-2 and the virus was detected by qPCR in body and head samples. Data were analyzed with the Statistical Package for the Social Sciences version 17. Results: IR varied from 40.0% to 82.5% in 2009 and 60.0% to 100.0% in 2011. VC ranged from 25.0% to 77.5% in 2009 and 25.0% to 80.0% in 2011. DIR oscillated from 68.7% to 100.0% in 2009 and 38.4% to 86.8 in 2011. When the results were evaluated by a logistic model using IR as covariate, North, Barreiro, South-Central and Venda Nova showed the strongest association in 2009. In 2011, a similar association was observed for South-Central, Venda Nova, West and Northeast regions. Using VC as covariate, South-Central and Venda Nova showed the most relevant association in 2009. In 2011, South-Central, Venda Nova and Barreiro presented the greatest revelation associations. When DIR data were analyzed by logistic regression models, Pampulha, South-Central, Venda Nova, West, Northeast and East (2009) as well as South-Central, Venda Nova and West (2011) were the districts showing the strongest associations. Conclusions: We conclude that Ae. aegypti populations from Belo Horizonte exhibit wide variation in vector competence to transmit dengue. Therefore, vector control strategies should be adapted to the available data for each region. Further analysis should be conducted to better understand the reasons for this large variability in vector competence and how these parameters correlate with epidemiological findings in subsequent years.Dengue virus (DENV)Aedes aegyptiField populationInfection rateVector competenceDisseminated infection rateinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINAL2014_192.pdf2014_192.pdfapplication/pdf475160https://www.arca.fiocruz.br/bitstream/icict/10143/2/2014_192.pdf2672072979c3d9d1b272986733bd5042MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82352https://www.arca.fiocruz.br/bitstream/icict/10143/3/license.txtafbdf7d7a9bcf771a1cc7edf5f618413MD53TEXT2014_192.pdf.txt2014_192.pdf.txtExtracted texttext/plain37837https://www.arca.fiocruz.br/bitstream/icict/10143/4/2014_192.pdf.txtdfb375fc45794112ca71c4c5fd4a2182MD54icict/101432019-06-19 10:07:47.175oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-06-19T13:07:47Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
title Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
spellingShingle Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
Gonçalves, Caroline Macedo
Dengue virus (DENV)
Aedes aegypti
Field population
Infection rate
Vector competence
Disseminated infection rate
title_short Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
title_full Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
title_fullStr Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
title_full_unstemmed Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
title_sort Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city
author Gonçalves, Caroline Macedo
author_facet Gonçalves, Caroline Macedo
Melo, Fabrício Freire de
Bezerra, Juliana Maria Trindade
Chaves, Bárbara Aparecida
Silva, Breno M
Silva, Luciana D
Pessanha, José EM
Arias, Jorge R
Secundino, Nágila Francinete Costa
Norris, Douglas E
Pimenta, Paulo Filemon Paolucci
author_role author
author2 Melo, Fabrício Freire de
Bezerra, Juliana Maria Trindade
Chaves, Bárbara Aparecida
Silva, Breno M
Silva, Luciana D
Pessanha, José EM
Arias, Jorge R
Secundino, Nágila Francinete Costa
Norris, Douglas E
Pimenta, Paulo Filemon Paolucci
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gonçalves, Caroline Macedo
Melo, Fabrício Freire de
Bezerra, Juliana Maria Trindade
Chaves, Bárbara Aparecida
Silva, Breno M
Silva, Luciana D
Pessanha, José EM
Arias, Jorge R
Secundino, Nágila Francinete Costa
Norris, Douglas E
Pimenta, Paulo Filemon Paolucci
dc.subject.en.pt_BR.fl_str_mv Dengue virus (DENV)
Aedes aegypti
Field population
Infection rate
Vector competence
Disseminated infection rate
topic Dengue virus (DENV)
Aedes aegypti
Field population
Infection rate
Vector competence
Disseminated infection rate
description Fundação Oswaldo Cruz. Laboratorio de Entomologia Médica. Belo Horizonte, MG, Brazil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2015-04-30T14:26:21Z
dc.date.available.fl_str_mv 2015-04-30T14:26:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GONÇALVES, Caroline Macedo et al. Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city. Parasites & Vectors, v. 7, p. 320, 2014
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/10143
dc.identifier.issn.none.fl_str_mv 1756-3305
dc.identifier.doi.none.fl_str_mv 10.1186/1756-3305-7-320
identifier_str_mv GONÇALVES, Caroline Macedo et al. Distinct variation in vector competence among nine field populations of Aedes aegypti from a Brazilian dengue-endemic risk city. Parasites & Vectors, v. 7, p. 320, 2014
1756-3305
10.1186/1756-3305-7-320
url https://www.arca.fiocruz.br/handle/icict/10143
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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