Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole

Detalhes bibliográficos
Autor(a) principal: Valle, A. C. F.
Data de Publicação: 2001
Outros Autores: Wanke, B., Lazéra, M. S., Monteiro, P. C. F., Viegas, M. L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/32908
Resumo: Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ, Brasil.
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spelling Valle, A. C. F.Wanke, B.Lazéra, M. S.Monteiro, P. C. F.Viegas, M. L.2019-05-02T13:51:49Z2019-05-02T13:51:49Z2001VALLE, Antonio Carlos Francesconi do et al. Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole. Revista do Instituto de Medicina Tropical de São Paulo, v. 43, n. 4, p. 233-236, July/Aug. 2001.0036-4665https://www.arca.fiocruz.br/handle/icict/3290810.1590/S0036-466520010004000121678-9946engUniversidade de São PauloEntomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazoleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Micologia. Rio de Janeiro, RJ, Brasil.Hospital da Lagoa. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Seguridade Social. Rio de Janeiro, RJ, Brasil.Rhinoentomophthoramycosis caused by Conidiobolus coronatus in a 61-year old woman was unsuccessfully treated during 8 years with all the antifungals available in the Brazilian market, including potassium iodide for 1 month, sulfamethoxazole plus trimethoprim for 2 months, amphotericin B, total dose of 1130 mg, cetoconazole, 400 mg/day for 6 months, fluconazole, 200 mg/day, for at least 2 months and, itraconazole, 400 mg/day for 2 months, followed by 200 mg/day for 4 more months. Complete clinical and mycological cure was achieved using itraconazol 400 mg/day in association with fluconazol 200 mg/day during 24 months. After cure she was submitted to plastic surgery to repair her facial deformation. Today she remains clinically and mycologically cured after 59/60 months (5 years!) without any specific antifungal. We thus suggest the use of the combination of itraconazole and fluconazole as an additional option for the treatment of this mycosis.EntomophthoramycosisZygomycosisCombination triazole treatmentRhinoentomophthoramycosisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/32908/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Valle_Antonio_etal_INI_2001.pdfve_Valle_Antonio_etal_INI_2001.pdfapplication/pdf150426https://www.arca.fiocruz.br/bitstream/icict/32908/2/ve_Valle_Antonio_etal_INI_2001.pdf0980a51b0b76155ac24b86e5aa5c7ab7MD52TEXTve_Valle_Antonio_etal_INI_2001.pdf.txtve_Valle_Antonio_etal_INI_2001.pdf.txtExtracted texttext/plain16644https://www.arca.fiocruz.br/bitstream/icict/32908/3/ve_Valle_Antonio_etal_INI_2001.pdf.txt2b4957a3b22e2e5b0b2ad9cb24c4c000MD53icict/329082019-05-03 02:01:14.477oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-05-03T05:01:14Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
title Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
spellingShingle Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
Valle, A. C. F.
Entomophthoramycosis
Zygomycosis
Combination triazole treatment
Rhinoentomophthoramycosis
title_short Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
title_full Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
title_fullStr Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
title_full_unstemmed Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
title_sort Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole
author Valle, A. C. F.
author_facet Valle, A. C. F.
Wanke, B.
Lazéra, M. S.
Monteiro, P. C. F.
Viegas, M. L.
author_role author
author2 Wanke, B.
Lazéra, M. S.
Monteiro, P. C. F.
Viegas, M. L.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Valle, A. C. F.
Wanke, B.
Lazéra, M. S.
Monteiro, P. C. F.
Viegas, M. L.
dc.subject.en.pt_BR.fl_str_mv Entomophthoramycosis
Zygomycosis
Combination triazole treatment
Rhinoentomophthoramycosis
topic Entomophthoramycosis
Zygomycosis
Combination triazole treatment
Rhinoentomophthoramycosis
description Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Laboratório de Epidemiologia Clínica. Rio de Janeiro, RJ, Brasil.
publishDate 2001
dc.date.issued.fl_str_mv 2001
dc.date.accessioned.fl_str_mv 2019-05-02T13:51:49Z
dc.date.available.fl_str_mv 2019-05-02T13:51:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv VALLE, Antonio Carlos Francesconi do et al. Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole. Revista do Instituto de Medicina Tropical de São Paulo, v. 43, n. 4, p. 233-236, July/Aug. 2001.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/32908
dc.identifier.issn.pt_BR.fl_str_mv 0036-4665
dc.identifier.doi.none.fl_str_mv 10.1590/S0036-46652001000400012
dc.identifier.eissn.none.fl_str_mv 1678-9946
identifier_str_mv VALLE, Antonio Carlos Francesconi do et al. Entomophthoramycosis by Conidiobolus coronatus: report of a case successfully treated with the combination of itraconazole and fluconazole. Revista do Instituto de Medicina Tropical de São Paulo, v. 43, n. 4, p. 233-236, July/Aug. 2001.
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