Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review

Detalhes bibliográficos
Autor(a) principal: Malta, Monica Siqueira
Data de Publicação: 2008
Outros Autores: Strathdee, Steffanie Anne, Magnanini, Monica Maria Ferreira, Bastos, Francisco Inácio Pinkusfeld Monteiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/1377
Resumo: Oswaldo Cruz Foundation. Sergio Arouca School of Public Health. Social Science Department. Rio de Janeiro, RJ, Brazil
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spelling Malta, Monica SiqueiraStrathdee, Steffanie AnneMagnanini, Monica Maria FerreiraBastos, Francisco Inácio Pinkusfeld Monteiro2010-11-25T13:40:13Z2010-11-25T13:40:13Z2008MALTA, Monica Siqueira et al. Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic. Addiction, 103, 1242–1257.https://www.arca.fiocruz.br/handle/icict/1377engAdherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleOswaldo Cruz Foundation. Sergio Arouca School of Public Health. Social Science Department. Rio de Janeiro, RJ, BrazilUniversity of Califórnia. School of Medicine. Department of Family and Preventive Medicine. Division of International Health and Cross Cultural Medicine. San Diego, CA, USAInstitute of Public Health Studies, Federal University of Rio de Janeiro (IESC/UFRJ), Rio de Janeiro, BrazilOswaldo Cruz Foundation. Center for Scientific and Technological Information. Health Information Department. Rio de Janeiro, RJ, BrazilAims Adherence to highly active antiretroviral therapy (HAART) is a key predictor of survival for human immunodeficiency virus (HIV)-infected people. Suboptimal adherence among marginalized populations such as HIV-positive drug users could be associated with clinical failure and the emergence of viral resistance. Objective To conduct a systematic review of studies assessing adherence to HAART among HIV-positive drug users (DU) and identify factors associated with non-adherence to HIV treatment. Data sources Seven electronic databases were searched for peerreviewed papers published in English, French, Spanish or Portuguese, from 1996 to 2007. Study selection and data abstraction Studies were excluded if they presented only qualitative data, were reviews themselves or assessed other populations without disaggregating data on DU. Findings on adherence were extracted and summarized. Data synthesis Forty-one studies were considered, which studied a total of 15 194 patients, the majority of whom were HIV-positive DU (n = 11 628, 76.5%). Twenty-two studies assessed adherence using patient self-reports, eight used pharmacy records, three used electronic monitoring [i.e. Medication Event Monitoring Systems (MEMS) caps], six studies used a combination of patient self-report, clinical data and MEMS-caps, and two analyzed secondary data. Overall, active substance use was associated with poor adherence, as well as depression and low social support. Higher adherence was found in patents receiving care in structured settings (e.g. directly observed therapy) and/or drug addiction treatment (especially substitution therapy). Conclusion While lower than other populations—especially among users of stimulants, incarcerated DU and patients with psychiatric comorbidities—adherence to HAART among HIV-positive DU can be achieved. 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dc.title.pt_BR.fl_str_mv Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
title Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
spellingShingle Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
Malta, Monica Siqueira
Adherence
antiretroviral therapy
Aids
drug use
HAART
HIV
methadone maintenance therapy
psychosocial support
systematic review
title_short Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
title_full Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
title_fullStr Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
title_full_unstemmed Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
title_sort Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic review
author Malta, Monica Siqueira
author_facet Malta, Monica Siqueira
Strathdee, Steffanie Anne
Magnanini, Monica Maria Ferreira
Bastos, Francisco Inácio Pinkusfeld Monteiro
author_role author
author2 Strathdee, Steffanie Anne
Magnanini, Monica Maria Ferreira
Bastos, Francisco Inácio Pinkusfeld Monteiro
author2_role author
author
author
dc.contributor.author.fl_str_mv Malta, Monica Siqueira
Strathdee, Steffanie Anne
Magnanini, Monica Maria Ferreira
Bastos, Francisco Inácio Pinkusfeld Monteiro
dc.subject.en.pt_BR.fl_str_mv Adherence
antiretroviral therapy
Aids
drug use
HAART
HIV
methadone maintenance therapy
psychosocial support
systematic review
topic Adherence
antiretroviral therapy
Aids
drug use
HAART
HIV
methadone maintenance therapy
psychosocial support
systematic review
description Oswaldo Cruz Foundation. Sergio Arouca School of Public Health. Social Science Department. Rio de Janeiro, RJ, Brazil
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2010-11-25T13:40:13Z
dc.date.available.fl_str_mv 2010-11-25T13:40:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv MALTA, Monica Siqueira et al. Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic. Addiction, 103, 1242–1257.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/1377
identifier_str_mv MALTA, Monica Siqueira et al. Adherence to antiretroviral therapy for human immunodeficiency virus/acquired immune deficiency syndrome among drug users: a systematic. Addiction, 103, 1242–1257.
url https://www.arca.fiocruz.br/handle/icict/1377
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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