A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/57049 |
Resumo: | Instituto Butantan. São Paulo, SP, Brazil / Instituto Butantan. Center of Toxins, Immune Response and Cell Signaling. São Paulo, SP, Brazil. |
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Elias, Maria CarolinaSlavov, Svetoslav NanevLima, Alex Ranieri JeronimoMartins, Antonio JorgeBarros, Claudia Renata Dos SantosMoretti, Debora BotequioAraujo, Eduardo L.Marqueze, Elaine CristinaRibeiro, GabrielaRibeiro, Gabriela Mauric FrossardBernardino, Jardelina Souza TodaoKoser, Jaqueline ReginatoClemente, Luan GasparCrispin, Luiz Aurelio CamposAlcantara, Luiz Carlos JuniorCoutinho, Luiz LehmannGiovanetti, MartaSilva, Quetura OliveiraMachado Neto, RaulHaddad, RicardoKashima, SimoneViala, Vincent LouisCovas, Dimas TadeuSampaio, Sandra Coccuzzo2023-02-13T18:11:02Z2023-02-13T18:11:02Z2023ELIAS, Maria Carolina et al. A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations. BMC Public Health, v. 23, p. 1-9, 2023.1471-2458https://www.arca.fiocruz.br/handle/icict/5704910.1186/s12889-022-14867-2engBioMed CentralA traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInstituto Butantan. São Paulo, SP, Brazil / Instituto Butantan. Center of Toxins, Immune Response and Cell Signaling. São Paulo, SP, Brazil.University of São Paulo. Ribeirão Preto Medical School. Blood Center of Ribeirão Preto. Ribeirão Preto, SP, Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Loccus. São Paulo, SP, Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Universidade de São Paulo. Centro de Genomica Funcional. Piracicaba, São Paulo, Brasil.Instituto Butantan. São Paulo, SP Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil.Universidade de São Paulo. Centro de Genomica Funcional. Piracicaba, São Paulo, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan. São Paulo, SP Brazil.University of São Paulo. Ribeirão Preto Medical School. Blood Center of Ribeirão Preto. Ribeirão Preto, SP, Brazil.Instituto Butantan. São Paulo, SP Brazil.University of São Paulo. Ribeirão Preto Medical School. Blood Center of Ribeirão Preto. Ribeirão Preto, SP, Brazil / Instituto Butantan. São Paulo, SP Brazil.Instituto Butantan, São Paulo, Brazil.Background: Brazil has been dramatically hit by the SARS-CoV-2 pandemic and is a world leader in COVID-19 morbidity and mortality. Additionally, the largest country of Latin America has been a continuous source of SARS-CoV-2 variants and shows extraordinary variability of the pandemic strains probably related to the country´s outstanding position as a Latin American economical and transportation hub. Not all regions of the country show sufficient infrastructure for SARS-CoV-2 diagnosis and genotyping which can negatively impact the pandemic response. Methods: Due to this reason and to disburden the diagnostic system of the inner São Paulo State, the Butantan Institute established the Mobile Laboratory (in Portuguese: LabMovel) for SARS-CoV-2 testing which started a trip of the most important "hotspots" of the most populous Brazilian region. The LabMovel initiated in two important cities of the State: Aparecida do Norte (an important religious center) and the Baixada Santista region which incorporates the port of Santos, the busiest in Latin America. The LabMovel was fully equipped with an automatized system for SARS-CoV-2 diagnosis and sequencing/genotyping. It also integrated the laboratory systems for patient records and results divulgation including in the Federal Brazilian Healthcare System. Results: Currently,16,678 samples were tested, among them 1,217 from Aparecida and 4,564 from Baixada Santista. We tracked the delta introductio in the tested regions with its high diversification. The established mobile SARS-CoV-2 laboratory had a major impact on the Public Health System of the included cities including timely delivery of the results to the healthcare agents and the Federal Healthcare system, evaluation of the vaccination status of the positive individuals in the background of exponential vaccination process in Brazil and scientific and technological divulgation of the fieldwork to the most vulnerable populations. Conclusions: The SARS-CoV-2 pandemic has demonstrated worldwide the importance of science to fight against this viral agent and the LabMovel shows that it is possible to integrate researchers, clinicians, healthcare workers and patients to take rapid actions that can in fact mitigate this and other epidemiological situations.BrazilCOVID-19LabMovelMolecular surveillanceReal-time detectionSARS-CoV-2info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/57049/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALA traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations.pdfA traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian 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| dc.title.en_US.fl_str_mv |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| title |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| spellingShingle |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations Elias, Maria Carolina Brazil COVID-19 LabMovel Molecular surveillance Real-time detection SARS-CoV-2 |
| title_short |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| title_full |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| title_fullStr |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| title_full_unstemmed |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| title_sort |
A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations |
| author |
Elias, Maria Carolina |
| author_facet |
Elias, Maria Carolina Slavov, Svetoslav Nanev Lima, Alex Ranieri Jeronimo Martins, Antonio Jorge Barros, Claudia Renata Dos Santos Moretti, Debora Botequio Araujo, Eduardo L. Marqueze, Elaine Cristina Ribeiro, Gabriela Ribeiro, Gabriela Mauric Frossard Bernardino, Jardelina Souza Todao Koser, Jaqueline Reginato Clemente, Luan Gaspar Crispin, Luiz Aurelio Campos Alcantara, Luiz Carlos Junior Coutinho, Luiz Lehmann Giovanetti, Marta Silva, Quetura Oliveira Machado Neto, Raul Haddad, Ricardo Kashima, Simone Viala, Vincent Louis Covas, Dimas Tadeu Sampaio, Sandra Coccuzzo |
| author_role |
author |
| author2 |
Slavov, Svetoslav Nanev Lima, Alex Ranieri Jeronimo Martins, Antonio Jorge Barros, Claudia Renata Dos Santos Moretti, Debora Botequio Araujo, Eduardo L. Marqueze, Elaine Cristina Ribeiro, Gabriela Ribeiro, Gabriela Mauric Frossard Bernardino, Jardelina Souza Todao Koser, Jaqueline Reginato Clemente, Luan Gaspar Crispin, Luiz Aurelio Campos Alcantara, Luiz Carlos Junior Coutinho, Luiz Lehmann Giovanetti, Marta Silva, Quetura Oliveira Machado Neto, Raul Haddad, Ricardo Kashima, Simone Viala, Vincent Louis Covas, Dimas Tadeu Sampaio, Sandra Coccuzzo |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Elias, Maria Carolina Slavov, Svetoslav Nanev Lima, Alex Ranieri Jeronimo Martins, Antonio Jorge Barros, Claudia Renata Dos Santos Moretti, Debora Botequio Araujo, Eduardo L. Marqueze, Elaine Cristina Ribeiro, Gabriela Ribeiro, Gabriela Mauric Frossard Bernardino, Jardelina Souza Todao Koser, Jaqueline Reginato Clemente, Luan Gaspar Crispin, Luiz Aurelio Campos Alcantara, Luiz Carlos Junior Coutinho, Luiz Lehmann Giovanetti, Marta Silva, Quetura Oliveira Machado Neto, Raul Haddad, Ricardo Kashima, Simone Viala, Vincent Louis Covas, Dimas Tadeu Sampaio, Sandra Coccuzzo |
| dc.subject.en.en_US.fl_str_mv |
Brazil COVID-19 LabMovel Molecular surveillance Real-time detection SARS-CoV-2 |
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Brazil COVID-19 LabMovel Molecular surveillance Real-time detection SARS-CoV-2 |
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Instituto Butantan. São Paulo, SP, Brazil / Instituto Butantan. Center of Toxins, Immune Response and Cell Signaling. São Paulo, SP, Brazil. |
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2023 |
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2023-02-13T18:11:02Z |
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2023-02-13T18:11:02Z |
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2023 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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ELIAS, Maria Carolina et al. A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations. BMC Public Health, v. 23, p. 1-9, 2023. |
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https://www.arca.fiocruz.br/handle/icict/57049 |
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1471-2458 |
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10.1186/s12889-022-14867-2 |
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ELIAS, Maria Carolina et al. A traveling SARS-CoV-2 laboratory as part of a pandemic response among vulnerable Brazilian populations. BMC Public Health, v. 23, p. 1-9, 2023. 1471-2458 10.1186/s12889-022-14867-2 |
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BioMed Central |
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BioMed Central |
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