Ticks, ivermectin, and experimental Chagas disease

Detalhes bibliográficos
Autor(a) principal: Dias, João Carlos Pinto
Data de Publicação: 2005
Outros Autores: Schofield, Christopher John, Machado, Evandro Marques de Menezes, Fernandes, Alexandre José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/5957
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.
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spelling Dias, João Carlos PintoSchofield, Christopher JohnMachado, Evandro Marques de MenezesFernandes, Alexandre José2012-12-11T16:19:47Z2012-12-11T16:19:47Z2005DIAS, João Carlos Pinto et al. Ticks, ivermectin, and experimental Chagas disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 829-832, Dec. 2005.0037-8682https://www.arca.fiocruz.br/handle/icict/5957engTicks, ivermectin, and experimental Chagas diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.London School of Hygiene and Tropical Medicine. Pathogen Molecular Biology Unit, London, UK.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.Following an infestation of dogticks in kennels housing dogs used for long-term studies of the pathogenesis of Chagas disease, we examined the effect of ivermectin treatment on the dogs, ticks, trypanosome parasites, and also on triatomine vectors of Chagas disease. Ivermectin treatment was highly effective in eliminating the ticks, but showed no apparent effect on the dogs nor on their trypanosome infection. Triatominae fed on the dogs soon after ivermectin treatment showed high mortality, but this effect quickly declined for bugs fed at successive intervals after treatment. In conclusion, although ivermectin treatment may have a transient effect on peridomestic populations of Triatominae, it is not the treatment of choice for this situation. The study also showed that although the dogticks could become infected with Trypanosoma cruzi, this only occurred when feeding on dogs in the acute phase of infection, and there was no evidence of subsequent parasite development in the ticks.Chagas diseaseTrypanosoma cruziRhipicephalus sanguineusivermectinTriatominaeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINAL17. Ticks, ivermectin, and experimental Chagas disease.pdf17. Ticks, ivermectin, and experimental Chagas disease.pdfapplication/pdf422714https://www.arca.fiocruz.br/bitstream/icict/5957/1/17.%20Ticks%2c%20ivermectin%2c%20and%20experimental%20Chagas%20disease.pdf4390afeb63edaf7da36607319ec80371MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81949https://www.arca.fiocruz.br/bitstream/icict/5957/2/license.txtaad6e5ff39a8b3723a1981fb3bcd1becMD52TEXT17. Ticks, ivermectin, and experimental Chagas disease.pdf.txt17. 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dc.title.pt_BR.fl_str_mv Ticks, ivermectin, and experimental Chagas disease
title Ticks, ivermectin, and experimental Chagas disease
spellingShingle Ticks, ivermectin, and experimental Chagas disease
Dias, João Carlos Pinto
Chagas disease
Trypanosoma cruzi
Rhipicephalus sanguineus
ivermectin
Triatominae
title_short Ticks, ivermectin, and experimental Chagas disease
title_full Ticks, ivermectin, and experimental Chagas disease
title_fullStr Ticks, ivermectin, and experimental Chagas disease
title_full_unstemmed Ticks, ivermectin, and experimental Chagas disease
title_sort Ticks, ivermectin, and experimental Chagas disease
author Dias, João Carlos Pinto
author_facet Dias, João Carlos Pinto
Schofield, Christopher John
Machado, Evandro Marques de Menezes
Fernandes, Alexandre José
author_role author
author2 Schofield, Christopher John
Machado, Evandro Marques de Menezes
Fernandes, Alexandre José
author2_role author
author
author
dc.contributor.author.fl_str_mv Dias, João Carlos Pinto
Schofield, Christopher John
Machado, Evandro Marques de Menezes
Fernandes, Alexandre José
dc.subject.en.pt_BR.fl_str_mv Chagas disease
Trypanosoma cruzi
Rhipicephalus sanguineus
ivermectin
Triatominae
topic Chagas disease
Trypanosoma cruzi
Rhipicephalus sanguineus
ivermectin
Triatominae
description Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Belo Horizonte, MG, Brasil / Fundação Oswaldo Cruz. Posto Avançado Emmanuel Dias. Bambui, MG, Brasil.
publishDate 2005
dc.date.issued.fl_str_mv 2005
dc.date.accessioned.fl_str_mv 2012-12-11T16:19:47Z
dc.date.available.fl_str_mv 2012-12-11T16:19:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv DIAS, João Carlos Pinto et al. Ticks, ivermectin, and experimental Chagas disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 829-832, Dec. 2005.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/5957
dc.identifier.issn.none.fl_str_mv 0037-8682
identifier_str_mv DIAS, João Carlos Pinto et al. Ticks, ivermectin, and experimental Chagas disease. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 100, n. 8, p. 829-832, Dec. 2005.
0037-8682
url https://www.arca.fiocruz.br/handle/icict/5957
dc.language.iso.fl_str_mv eng
language eng
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