Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA

Detalhes bibliográficos
Autor(a) principal: Lancaster, K.E.
Data de Publicação: 2023
Outros Autores: Stockton, Melissa, Hahn, J. A., Chanyachukul, T., Kwobah, E., Byakwaga, H., Carrieri, P., Murenzi, G., Perazzo, Hugo, Crabtree Ramírez, B., Haas, A., Mandiriri, A., Marbaniang, I., Jaquet, A., Parcesepe, A.
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/60653
Resumo: The Ohio State University. Columbus, USA.
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spelling Lancaster, K.E.Stockton, MelissaHahn, J. A.Chanyachukul, T.Kwobah, E.Byakwaga, H.Carrieri, P.Murenzi, G.Perazzo, HugoCrabtree Ramírez, B.Haas, A.Mandiriri, A.Marbaniang, I.Jaquet, A.Parcesepe, A.2023-10-03T00:19:57Z2023-10-03T00:19:57Z2023LANCASTER, K. E. et al. Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA. In: IAS CONFERENCE ON HIV SCIENCE, 12., Brisbane, Australia. [Abstracts...]. Australia, 2023. 1 p.https://www.arca.fiocruz.br/handle/icict/60653engHIVIeDEAPonto de atendimentoUso de álcoolHIVIeDEAPoint-of-careAlcohol useConcordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEAConcordância de biomarcadores auto-relatados e no ponto de atendimento de medidas de uso de álcool entre adultos mais velhos com HIV de países de baixa e média renda, a Rede de Pesquisa Sentinela da Iedeainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectThe Ohio State University. Columbus, USA.University of North Carolina at Chapel Hill. Chapel Hill, USA.Universirty of California San Francisco. San Francisco, USA.TREAT Asia/amfAR – The Foundation for AIDS Research. Bangkok, Thailand.Moi Teaching and Referral Hospital. Eldoret, Kenya.Mbarara University ISS Clinic. Mbarara, Uganda.Aix Marseille Univ. Marseille, France.Research for Development (RD Rwanda) and the Rwanda Military Hospital. Kigali, Rwanda.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil.Instituto Nacional de Ciencias Médicas y Nutrición. México City, Mexico.University of Bern. Institute of Social and Preventive Medicine (ISPM). Switzerland.Newlands Clinic. Harare, Zimbabwe.BJ Government Medical College-JHU Clinical Research Site. Maharashtra, India.University of Bordeaux. Bordeaux, France.University of North Carolina at Chapel Hill. Chapel Hill, USA.Background: Measuring alcohol use is challenging within HIV care services, particularly in low resource settings. Self-reported measurements of alcohol use are rapid and inexpensive yet highly susceptible to mismeasurement. Understanding the use of point-of-care (POC) urine biomarkers and their concordance with self-report will inform strategies for alcohol use measurement among older people with HIV (PWH) in low- and middle-income countries. Methods: We analyzed cross-sectional data from the International epidemiology Database to Evaluate AIDS (IeDEA) Sentinel Research Network (SRN) cohort of PWH aged =40 years from HIV clinics within the Asia-Pacific, Central/Latin America, and Africa regions. We assessed concordance of self-reported alcohol use and POC urine ethylglucuronide (uETG) testing (alcohol detectable up to prior 5 days). We examined the associations between self-reported alcohol measures and uETG using mixed-effect logistic regression controlling for age and sex (fixed) and clinic site (random). We fitted 5 models of uEtG positivity: alcohol use frequency, number of drinks on typical day, binge drinking frequency, unhealthy alcohol use (AUDIT-C =3 for women, =4 for men), and possible alcohol use disorder (AUDIT =13 for women, =15 for men). Results: Of the 2059 participants, 46% (n=945) were men, 52% (n=1,067) reported drinking alcohol, and 20% (n=406) reported unhealthy drinking. A total of 251 participants (12%) tested uEtG positive, with 140 (56%) reporting unhealthy drinking and 111 (44%) not reporting unhealthy drinking. Concordance of self-reported unhealthy alcohol use and uEtG was 82% (kappa=0.32) with differences by sex (women: 87%; kappa=0.29; men: 75%; kappa=0.17). In multivariate models, all measures of self-reported alcohol use were associated with positive uEtG. Conclusions: Though lower among men when compared to women, the overall concordance between self-reported alcohol use and urine POC biomarker was moderate. Alternative biomarkers with longer detection windows should be used to validate and potentially augment self-reported measures. Further approaches for incorporating objective biomarkers should be explored for both epidemiologic and interventional efforts addressing alcohol use among PWH in low resource settings.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/60653/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALConcordance_Hugo_Perazzo.pdfConcordance_Hugo_Perazzo.pdfapplication/pdf834508https://www.arca.fiocruz.br/bitstream/icict/60653/2/Concordance_Hugo_Perazzo.pdff27b648026f54030d1a11dae3b0e3965MD52icict/606532023-10-02 21:21:34.754oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-10-03T00:21:34Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
dc.title.alternative.en_US.fl_str_mv Concordância de biomarcadores auto-relatados e no ponto de atendimento de medidas de uso de álcool entre adultos mais velhos com HIV de países de baixa e média renda, a Rede de Pesquisa Sentinela da Iedea
title Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
spellingShingle Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
Lancaster, K.E.
HIV
IeDEA
Ponto de atendimento
Uso de álcool
HIV
IeDEA
Point-of-care
Alcohol use
title_short Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
title_full Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
title_fullStr Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
title_full_unstemmed Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
title_sort Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA
author Lancaster, K.E.
author_facet Lancaster, K.E.
Stockton, Melissa
Hahn, J. A.
Chanyachukul, T.
Kwobah, E.
Byakwaga, H.
Carrieri, P.
Murenzi, G.
Perazzo, Hugo
Crabtree Ramírez, B.
Haas, A.
Mandiriri, A.
Marbaniang, I.
Jaquet, A.
Parcesepe, A.
author_role author
author2 Stockton, Melissa
Hahn, J. A.
Chanyachukul, T.
Kwobah, E.
Byakwaga, H.
Carrieri, P.
Murenzi, G.
Perazzo, Hugo
Crabtree Ramírez, B.
Haas, A.
Mandiriri, A.
Marbaniang, I.
Jaquet, A.
Parcesepe, A.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Lancaster, K.E.
Stockton, Melissa
Hahn, J. A.
Chanyachukul, T.
Kwobah, E.
Byakwaga, H.
Carrieri, P.
Murenzi, G.
Perazzo, Hugo
Crabtree Ramírez, B.
Haas, A.
Mandiriri, A.
Marbaniang, I.
Jaquet, A.
Parcesepe, A.
dc.subject.other.en_US.fl_str_mv HIV
IeDEA
Ponto de atendimento
Uso de álcool
topic HIV
IeDEA
Ponto de atendimento
Uso de álcool
HIV
IeDEA
Point-of-care
Alcohol use
dc.subject.en.en_US.fl_str_mv HIV
IeDEA
Point-of-care
Alcohol use
description The Ohio State University. Columbus, USA.
publishDate 2023
dc.date.accessioned.fl_str_mv 2023-10-03T00:19:57Z
dc.date.available.fl_str_mv 2023-10-03T00:19:57Z
dc.date.issued.fl_str_mv 2023
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
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status_str publishedVersion
dc.identifier.citation.fl_str_mv LANCASTER, K. E. et al. Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA. In: IAS CONFERENCE ON HIV SCIENCE, 12., Brisbane, Australia. [Abstracts...]. Australia, 2023. 1 p.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/60653
identifier_str_mv LANCASTER, K. E. et al. Concordance of self-reported and point-of-care biomarkers of alcohol use measures among older adults with HIV from low- and middle-income countries, the Sentinel Research Network of IeDEA. In: IAS CONFERENCE ON HIV SCIENCE, 12., Brisbane, Australia. [Abstracts...]. Australia, 2023. 1 p.
url https://www.arca.fiocruz.br/handle/icict/60653
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/60653/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/60653/2/Concordance_Hugo_Perazzo.pdf
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