A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy

Detalhes bibliográficos
Autor(a) principal: Signorini, Dario José Hart Pontes
Data de Publicação: 2011
Outros Autores: Oliveira Netto, Ana Maria Schmidt de, Monteiro, Michelle Carreira Miranda, Gabbay, Sergio, Andrade, Marion de Fátima Castro de, Bastos, Francisco Inácio Pinkusfeld Monteiro, Codeço, Cláudia Torres
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/3869
Resumo: Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil.
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spelling Signorini, Dario José Hart PontesOliveira Netto, Ana Maria Schmidt deMonteiro, Michelle Carreira MirandaGabbay, SergioAndrade, Marion de Fátima Castro deBastos, Francisco Inácio Pinkusfeld MonteiroCodeço, Cláudia Torres2012-05-02T02:53:30Z2012-05-02T02:53:30Z2011SIGNORINI, Dario José Hart Pontes et al. A Comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy. Journal of the International Association of Physicians in AIDS Care, Chicago, v. 10, n. 6, p. 351-356, Nov./Dec. 2011.1545-1097https://www.arca.fiocruz.br/handle/icict/386910.1177/1545109711399660engSAGE PublicationsA comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil.Instituto Brasileiro de Ultra-Sonografia. Rio de Janeiro, RJ, Brasil.Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil.Instituto Brasileiro de Ultra-Sonografia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Comunicação e Informação Científica e Tecnológica em Saúde. Departamento de Informações em Saúde. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Presidência. Programa de Computação Científica. Rio de Janeiro, RJ, Brasil.The study evaluated the use of sonographic measurements as an alternative to assessments based on clinical or other imaging techniques for the diagnosis of body-fat abnormalities. The study enrolled 179 HIV-infected patients, 81 (45.3%) of them diagnosed as lipodystrophy (LD)-positive based on a clinical standard questionnaire. Association between clinical LD and sonographic measurements of face, right upper limb, subcutaneous abdomen, and visceral compartments was evaluated by multiple logistic regression. The predicted probability of the logistic model was 0.64, corresponding to a maximum sensitivity of 69.1% (58%-79%), a specificity of 94.9% (88%-98%), and to positive and negative predictive values of 92% (82%-97%) and 79% (70%-86%), respectively. Kappa measure of concordance was 65% (54%-77%). Low sensitivity poses a problem for the use of sonography to detect LD in the clinical routine as a single exam, speaking in favor of the combined use of clinical and sonographic measurements over time.HIV-associated lipodystrophy syndromeAnti-HIV agentsROC curveUltrasonographyLogistic modelsSensitivity and specificitySíndrome de Lipodistrofia Associada ao HIV/diagnósticoFármacos Anti-HIVCurva ROCQuestionárioModelos LogísticosSensibilidade e Especificidadeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALComparison_sonographic_assessments_clinical_HIV.pdfComparison_sonographic_assessments_clinical_HIV.pdfapplication/pdf358917https://www.arca.fiocruz.br/bitstream/icict/3869/1/Comparison_sonographic_assessments_clinical_HIV.pdf0ff94343e7d6a24c1366e3e96f1b4c08MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/3869/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTComparison_sonographic_assessments_clinical_HIV.pdf.txtComparison_sonographic_assessments_clinical_HIV.pdf.txtExtracted texttext/plain31186https://www.arca.fiocruz.br/bitstream/icict/3869/5/Comparison_sonographic_assessments_clinical_HIV.pdf.txt05c1a0f7827c29e0f95aea0b157800fdMD55THUMBNAILComparison_sonographic_assessments_clinical_HIV.pdf.jpgComparison_sonographic_assessments_clinical_HIV.pdf.jpgGenerated Thumbnailimage/jpeg2087https://www.arca.fiocruz.br/bitstream/icict/3869/4/Comparison_sonographic_assessments_clinical_HIV.pdf.jpgdb1144d7dc1a4dd18f2aeab6489ab92fMD54icict/38692023-08-01 16:55:00.386oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-08-01T19:55Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
title A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
spellingShingle A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
Signorini, Dario José Hart Pontes
HIV-associated lipodystrophy syndrome
Anti-HIV agents
ROC curve
Ultrasonography
Logistic models
Sensitivity and specificity
Síndrome de Lipodistrofia Associada ao HIV/diagnóstico
Fármacos Anti-HIV
Curva ROC
Questionário
Modelos Logísticos
Sensibilidade e Especificidade
title_short A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
title_full A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
title_fullStr A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
title_full_unstemmed A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
title_sort A comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy
author Signorini, Dario José Hart Pontes
author_facet Signorini, Dario José Hart Pontes
Oliveira Netto, Ana Maria Schmidt de
Monteiro, Michelle Carreira Miranda
Gabbay, Sergio
Andrade, Marion de Fátima Castro de
Bastos, Francisco Inácio Pinkusfeld Monteiro
Codeço, Cláudia Torres
author_role author
author2 Oliveira Netto, Ana Maria Schmidt de
Monteiro, Michelle Carreira Miranda
Gabbay, Sergio
Andrade, Marion de Fátima Castro de
Bastos, Francisco Inácio Pinkusfeld Monteiro
Codeço, Cláudia Torres
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Signorini, Dario José Hart Pontes
Oliveira Netto, Ana Maria Schmidt de
Monteiro, Michelle Carreira Miranda
Gabbay, Sergio
Andrade, Marion de Fátima Castro de
Bastos, Francisco Inácio Pinkusfeld Monteiro
Codeço, Cláudia Torres
dc.subject.en.pt_BR.fl_str_mv HIV-associated lipodystrophy syndrome
Anti-HIV agents
ROC curve
Ultrasonography
Logistic models
Sensitivity and specificity
topic HIV-associated lipodystrophy syndrome
Anti-HIV agents
ROC curve
Ultrasonography
Logistic models
Sensitivity and specificity
Síndrome de Lipodistrofia Associada ao HIV/diagnóstico
Fármacos Anti-HIV
Curva ROC
Questionário
Modelos Logísticos
Sensibilidade e Especificidade
dc.subject.decs.pt_BR.fl_str_mv Síndrome de Lipodistrofia Associada ao HIV/diagnóstico
Fármacos Anti-HIV
Curva ROC
Questionário
Modelos Logísticos
Sensibilidade e Especificidade
description Universidade Federal do Estado do Rio de Janeiro. Hospital Universitário Gaffrée e Guinle. Rio de Janeiro, RJ, Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2012-05-02T02:53:30Z
dc.date.available.fl_str_mv 2012-05-02T02:53:30Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv SIGNORINI, Dario José Hart Pontes et al. A Comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy. Journal of the International Association of Physicians in AIDS Care, Chicago, v. 10, n. 6, p. 351-356, Nov./Dec. 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/3869
dc.identifier.issn.none.fl_str_mv 1545-1097
dc.identifier.doi.none.fl_str_mv 10.1177/1545109711399660
identifier_str_mv SIGNORINI, Dario José Hart Pontes et al. A Comparison of sonographic assessments and clinical questionnaire in the diagnosis of HIV-associated lipodystrophy. Journal of the International Association of Physicians in AIDS Care, Chicago, v. 10, n. 6, p. 351-356, Nov./Dec. 2011.
1545-1097
10.1177/1545109711399660
url https://www.arca.fiocruz.br/handle/icict/3869
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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