Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/7958 |
Resumo: | Fundação de Amparo à Pesquisa do Estado de São Paulo,Conselho Nacional para o Desenvolvimento Científico e Tecnológico, COLCIENCIAS, National Institute of Allergy and Infectious Diseases |
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Melo, Luciane Moreno StortiCosta, Daniela Reis daNeiras, Wanessa Cristina de SouzaCassiano, Gustavo CapattiCouto, Vanja Suely Calvosa D’AlmeidaPóvoa, Marinete MarinsSoares, Irene da SilvaCarvalho, Luzia Helena deArevalo-Herrera, MyrianHerrera, SócratesRossit, Andrea Regina BaptistaCordeiro, José AntonioMattos, Luiz Carlos deMachado, Ricardo Luiz Dantas2014-07-14T19:23:18Z2014-07-14T19:23:18Z2012STORTI MELO, Luciane Moreno et al. Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax. Acta Tropica. 2012, vol.121, pp. 152-155.0001-706Xhttps://www.arca.fiocruz.br/handle/icict/795810.1016/j.actatropica.2011.10.009Fundação de Amparo à Pesquisa do Estado de São Paulo,Conselho Nacional para o Desenvolvimento Científico e Tecnológico, COLCIENCIAS, National Institute of Allergy and Infectious DiseasesUniversidade Federal de Sergipe. Departamento de Biociências. Itabaiana, SE, Brazil/Faculdade de Medicina de São José do Rio Preto. Departamento de Doenças Dermatológicas, Infecciosas e Parasitárias. Centro de Investigação de Microrganismos. José do Rio Preto, SP, BrazilFaculdade de Medicina de São José do Rio Preto. Departamento de Doenças Dermatológicas, Infecciosas e Parasitárias. Centro de Investigação de Microrganismos. José do Rio Preto, SP, BrazilFaculdade de Medicina de São José do Rio Preto. Departamento de Doenças Dermatológicas, Infecciosas e Parasitárias. Centro de Investigação de Microrganismos. São José do Rio Preto, SP, Brazil/Universidade Federal do Triângulo Mineiro. Instituto de Ciências Exatas, Naturais e Educação. Uberaba, MG, BrazilFaculdade de Medicina de São José do Rio Preto. Departamento de Doenças Dermatológicas, Infecciosas e Parasitárias. Centro de Investigação de Microrganismos.José do Rio Preto, SP, Brazil/Universidade Estadual Paulista Júlio Mesquita Filho. Pós Graduação em Genética. São José do Rio Preto, SP, BrazilMinistério da Saúde. Núcleo Estadual do Amapá. Macapá, AP, BrazilInstituto Evandro Chagas. Laboratório de Pesquisas Básicas em Malária. Secretaria de Vigilância em Saúde. Ananindeua, Pará, BrazilUniversidade de São Paulo. Faculdade de Ciências Farmacêuticas. São Paulo, SP, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou Laboratório de Malária. Belo Horizonte, MG, BrazilUniversidad del Valle. Facultad de Salud. Instituto de Inmunología. Cali, ColombiaUniversidad del Valle. Facultad de Salud. Instituto de Inmunología. Cali, ColombiaUniversidade Federal Fluminense.Instituto Biomédico. Departamento de Microbiologia e Parasitologia. Niterói, RJ, BrazilFaculdade de Medicina de São José do Rio Preto. Departamento de Epidemiologia. São José do Rio Preto, São Paulo, BrazilFaculdade de Medicina de São José do Rio Preto. Departamento de Biologia Molecular. Laboratório de Imunohematologia. São José do Rio Preto, SP, BrazilFaculdade de Medicina de São José do Rio Preto. Departamento de Doenças Dermatológicas, Infecciosas e Parasitárias. Centro de Investigação de Microrganismos. José do Rio Preto, SP, BrazilWe evaluated the influence of allelic frequency of the human leukocyte antigen (HLA) -DRB1 on the acquisition of antibody response against malaria sporozoite and merozoite peptides in patients with Plasmodium vivax malaria acquired in endemic areas of Brazil. IgG antibodies were detected by enzyme-linked immunosorbent assay against four peptides of circumsporozoite protein (CSP) (amino, carboxyl, and VK210 and VK247 repeats) and peptides of merozoite surface protein 1 (MSP-1), apical membrane antigen 1 (AMA-1), and Duffy-binding protein (DBP). We found an association between HLA-DR3 and HLA-DR5 alleles and lack of antibody response to CSP amino terminal, as well as an association between HLA-DR3 and the highest antibody response to MSP1 (Pv200L). In conclusion, we suggest a potential regulatory role of the HLA-DRB1 alleles in the production of antibodies to a conserved region of P. vivax CSP and MSP1 in Brazilian population exposed to malaria.engElsevier IncorporationInfluence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivaxinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePlasmodium vivaxHLA-DRB1Antibody responseinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALInfluence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax.pdfInfluence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax.pdfapplication/pdf1086483https://www.arca.fiocruz.br/bitstream/icict/7958/1/Influence%20of%20HLA-DRB-1%20alleles%20on%20the%20production%20of%20antibody%20against%20CSP%2c%20MSP-1%2c%20AMA-1%2c%20and%20DBP%20in%20Brazilian%20individuals%20naturally%20infected%20with%20Plasmodium%20vivax.pdfd221781096c01dc30756f28e09484e49MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7958/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTInfluence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax.pdf.txtInfluence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax.pdf.txtExtracted texttext/plain4https://www.arca.fiocruz.br/bitstream/icict/7958/3/Influence%20of%20HLA-DRB-1%20alleles%20on%20the%20production%20of%20antibody%20against%20CSP%2c%20MSP-1%2c%20AMA-1%2c%20and%20DBP%20in%20Brazilian%20individuals%20naturally%20infected%20with%20Plasmodium%20vivax.pdf.txtff4c8ff01d544500ea4bfea43e6108c1MD53icict/79582018-04-05 23:45:40.598oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-04-06T02:45:40Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| title |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| spellingShingle |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax Melo, Luciane Moreno Storti Plasmodium vivax HLA-DRB1 Antibody response |
| title_short |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| title_full |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| title_fullStr |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| title_full_unstemmed |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| title_sort |
Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax |
| author |
Melo, Luciane Moreno Storti |
| author_facet |
Melo, Luciane Moreno Storti Costa, Daniela Reis da Neiras, Wanessa Cristina de Souza Cassiano, Gustavo Capatti Couto, Vanja Suely Calvosa D’Almeida Póvoa, Marinete Marins Soares, Irene da Silva Carvalho, Luzia Helena de Arevalo-Herrera, Myrian Herrera, Sócrates Rossit, Andrea Regina Baptista Cordeiro, José Antonio Mattos, Luiz Carlos de Machado, Ricardo Luiz Dantas |
| author_role |
author |
| author2 |
Costa, Daniela Reis da Neiras, Wanessa Cristina de Souza Cassiano, Gustavo Capatti Couto, Vanja Suely Calvosa D’Almeida Póvoa, Marinete Marins Soares, Irene da Silva Carvalho, Luzia Helena de Arevalo-Herrera, Myrian Herrera, Sócrates Rossit, Andrea Regina Baptista Cordeiro, José Antonio Mattos, Luiz Carlos de Machado, Ricardo Luiz Dantas |
| author2_role |
author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Melo, Luciane Moreno Storti Costa, Daniela Reis da Neiras, Wanessa Cristina de Souza Cassiano, Gustavo Capatti Couto, Vanja Suely Calvosa D’Almeida Póvoa, Marinete Marins Soares, Irene da Silva Carvalho, Luzia Helena de Arevalo-Herrera, Myrian Herrera, Sócrates Rossit, Andrea Regina Baptista Cordeiro, José Antonio Mattos, Luiz Carlos de Machado, Ricardo Luiz Dantas |
| dc.subject.en.pt_BR.fl_str_mv |
Plasmodium vivax HLA-DRB1 Antibody response |
| topic |
Plasmodium vivax HLA-DRB1 Antibody response |
| description |
Fundação de Amparo à Pesquisa do Estado de São Paulo,Conselho Nacional para o Desenvolvimento Científico e Tecnológico, COLCIENCIAS, National Institute of Allergy and Infectious Diseases |
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2012 |
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2012 |
| dc.date.accessioned.fl_str_mv |
2014-07-14T19:23:18Z |
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2014-07-14T19:23:18Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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STORTI MELO, Luciane Moreno et al. Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax. Acta Tropica. 2012, vol.121, pp. 152-155. |
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https://www.arca.fiocruz.br/handle/icict/7958 |
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0001-706X |
| dc.identifier.doi.none.fl_str_mv |
10.1016/j.actatropica.2011.10.009 |
| identifier_str_mv |
STORTI MELO, Luciane Moreno et al. Influence of HLA-DRB-1 alleles on the production of antibody against CSP, MSP-1, AMA-1, and DBP in Brazilian individuals naturally infected with Plasmodium vivax. Acta Tropica. 2012, vol.121, pp. 152-155. 0001-706X 10.1016/j.actatropica.2011.10.009 |
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Elsevier Incorporation |
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