Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/53379 |
Resumo: | Diagnostics - PATH. Seattle, WA, USA. |
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Zobrist, StephanieOliveira-Silva, MichelleVieira, Alexia MartinesBansil, PoojaGerth-Guyette, EmilyLeader, Brandon T.Golden, AllisonSlater, HannahCruz, Catherine Duran de LucenaGarbin, EduardoSagalovsky, MarianaPal, SampaGupta, VinWolansky, LeoDall'Acqua, Deusilene Souza VieiraNaveca, Felipe GomesNascimento, Valdinete Alves doVillalobos Salcedo, Juan MiguelDrain, Paul K.Costa, Alexandre Dias TavaresDomingo, Gonzalo J.Pereira, Dhélio2022-06-20T18:54:40Z2022-06-20T18:54:40Z2022ZOBRIST, Stephanie et al. Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations. The Journal of Infectious Diseases, p. 1-11, 20 May 2022.0022-1899https://www.arca.fiocruz.br/handle/icict/5337910.1093/infdis/jiac2041537-6613engOxford University PressPorto VelhoRondôniaAllplex SARS-CoV-2 assaySalivaDirectTeste PADRÃO Q COVID-19 AgLumiraDx SARS-CoV-2 Ag testPorto VelhoRondôniaAllplex SARS-CoV-2 assaySalivaDirectSD Biosensor STANDARD Q COVID-19 AgLumiraDx SARS-CoV-2 Ag testPorto VelhoRondôniaEnsayo Allplex SARS-CoV-2SalivaDirectSD Biosensor STANDARD Q COVID-19 AgLa Prueba LumiraDx SARS-CoV-2 AgSARS-CoV-2COVID-19Reação em Cadeia da Polimerase Via Transcriptase ReversaKit de Reagentes para DiagnósticoScreening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleDiagnostics - PATH. Seattle, WA, USA.Centro de Pesquisa em Medicina Tropical. Porto Velho, RO, Brasil.Centro de Pesquisa em Medicina Tropical. Porto Velho, RO, Brasil.Diagnostics - PATH. Seattle, WA, USA.Diagnostics - PATH. Seattle, WA, USA.Diagnostics - PATH. Seattle, WA, USA.Diagnostics - PATH. Seattle, WA, USA.Diagnostics - PATH. Seattle, WA, USA.Centro de Pesquisa em Medicina Tropical. Porto Velho, RO, Brasil.Centro de Pesquisa em Medicina Tropical. Porto Velho, RO, Brasil.Diagnostics - PATH. Seattle, WA, USA.Diagnostics - PATH. Seattle, WA, USA.Amazon.com. Seattle, WA, USA.The Rockefeller Foundation. Pandemic Prevention Institute. New York, NY, USA.Fundação Oswaldo Cruz. Fiocruz Rondônia. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brasil.Fundação Oswaldo Cruz. Fiocruz Rondônia. Porto Velho, RO, Brasil.University of Washington. Departments of Global Health and Medicine. Seattle, WA, USA.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Diagnostics - PATH. Seattle, WA, USA.Centro de Pesquisa em Medicina Tropical. Porto Velho, RO, Brasil.Background. Point-of-care and decentralized testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical to inform public health responses. Performance evaluations in priority use cases such as contact tracing can highlight trade-offs in test selection and testing strategies. Methods. A prospective diagnostic accuracy study was conducted among close contacts of coronavirus disease 2019 (COVID19) cases in Brazil. Two anterior nares swabs (ANS), a nasopharyngeal swab (NPS), and saliva were collected at all visits. Vaccination history and symptoms were assessed. Household contacts were followed longitudinally. Three rapid antigen tests and 1 molecular method were evaluated for usability and performance against reference reverse-transcription polymerase chain reaction (RT-PCR) on nasopharyngeal swab specimens. Results. Fifty index cases and 214 contacts (64 household) were enrolled. Sixty-five contacts were RT-PCR positive during ≥1 visit. Vaccination did not influence viral load. Gamma variants were most prevalent; Delta variants emerged increasingly during implementation. The overall sensitivity of evaluated tests ranged from 33% to 76%. Performance was higher among symptomatic cases and those with cycle threshold (Ct) values ,34 and lower among oligosymptomatic or asymptomatic cases. Assuming a 24-hour time to results for RT-PCR, the cumulative sensitivity of an anterior nares swab rapid antigen test was .70% and almost 90% after 4 days. Conclusions. The near-immediate time to results for antigen tests significantly offsets lower analytical sensitivity in settings where RT-PCR results are delayed or unavailable.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/53379/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINALjiac204OK2.pdfjiac204OK2.pdfapplication/pdf881347https://www.arca.fiocruz.br/bitstream/icict/53379/2/jiac204OK2.pdfac0b915ce92e1d184dbd05d5e9f591daMD52icict/533792022-11-17 10:26:57.58oai:www.arca.fiocruz.br:icict/53379Q0VTU8ODTyBOw4NPIEVYQ0xVU0lWQSBERSBESVJFSVRPUyBBVVRPUkFJUw0KDQpNYW5vZWwgQmFyYXRhLCBDUEY6IDA3MC43NjQuMzM3LTYxLCB2aW5jdWxhZG8gYSBGaW9jcnV6IFBhcmFuw6EgLSBJbnN0aXR1dG8gQ2FybG9zIENoYWdhcwoKQW8gYWNlaXRhciBvcyBURVJNT1MgZSBDT05EScOHw5VFUyBkZXN0YSBDRVNTw4NPLCBvIEFVVE9SIGUvb3UgVElUVUxBUiBkZSBkaXJlaXRvcwphdXRvcmFpcyBzb2JyZSBhIE9CUkEgZGUgcXVlIHRyYXRhIGVzdGUgZG9jdW1lbnRvOgoKKDEpIENFREUgZSBUUkFOU0ZFUkUsIHRvdGFsIGUgZ3JhdHVpdGFtZW50ZSwgw6AgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaLCBlbQpjYXLDoXRlciBwZXJtYW5lbnRlLCBpcnJldm9nw6F2ZWwgZSBOw4NPIEVYQ0xVU0lWTywgdG9kb3Mgb3MgZGlyZWl0b3MgcGF0cmltb25pYWlzIE7Dg08KQ09NRVJDSUFJUyBkZSB1dGlsaXphw6fDo28gZGEgT0JSQSBhcnTDrXN0aWNhIGUvb3UgY2llbnTDrWZpY2EgaW5kaWNhZGEgYWNpbWEsIGluY2x1c2l2ZSBvcyBkaXJlaXRvcwpkZSB2b3ogZSBpbWFnZW0gdmluY3VsYWRvcyDDoCBPQlJBLCBkdXJhbnRlIHRvZG8gbyBwcmF6byBkZSBkdXJhw6fDo28gZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCBlbQpxdWFscXVlciBpZGlvbWEgZSBlbSB0b2RvcyBvcyBwYcOtc2VzOwoKKDIpIEFDRUlUQSBxdWUgYSBjZXNzw6NvIHRvdGFsIG7Do28gZXhjbHVzaXZhLCBwZXJtYW5lbnRlIGUgaXJyZXZvZ8OhdmVsIGRvcyBkaXJlaXRvcyBhdXRvcmFpcwpwYXRyaW1vbmlhaXMgbsOjbyBjb21lcmNpYWlzIGRlIHV0aWxpemHDp8OjbyBkZSBxdWUgdHJhdGEgZXN0ZSBkb2N1bWVudG8gaW5jbHVpLCBleGVtcGxpZmljYXRpdmFtZW50ZSwKb3MgZGlyZWl0b3MgZGUgZGlzcG9uaWJpbGl6YcOnw6NvIGUgY29tdW5pY2HDp8OjbyBww7pibGljYSBkYSBPQlJBLCBlbSBxdWFscXVlciBtZWlvIG91IHZlw61jdWxvLAppbmNsdXNpdmUgZW0gUmVwb3NpdMOzcmlvcyBEaWdpdGFpcywgYmVtIGNvbW8gb3MgZGlyZWl0b3MgZGUgcmVwcm9kdcOnw6NvLCBleGliacOnw6NvLCBleGVjdcOnw6NvLApkZWNsYW1hw6fDo28sIHJlY2l0YcOnw6NvLCBleHBvc2nDp8OjbywgYXJxdWl2YW1lbnRvLCBpbmNsdXPDo28gZW0gYmFuY28gZGUgZGFkb3MsIHByZXNlcnZhw6fDo28sIGRpZnVzw6NvLApkaXN0cmlidWnDp8OjbywgZGl2dWxnYcOnw6NvLCBlbXByw6lzdGltbywgdHJhZHXDp8OjbywgZHVibGFnZW0sIGxlZ2VuZGFnZW0sIGluY2x1c8OjbyBlbSBub3ZhcyBvYnJhcyBvdQpjb2xldMOibmVhcywgcmV1dGlsaXphw6fDo28sIGVkacOnw6NvLCBwcm9kdcOnw6NvIGRlIG1hdGVyaWFsIGRpZMOhdGljbyBlIGN1cnNvcyBvdSBxdWFscXVlciBmb3JtYSBkZQp1dGlsaXphw6fDo28gbsOjbyBjb21lcmNpYWw7CgooMykgUkVDT05IRUNFIHF1ZSBhIGNlc3PDo28gYXF1aSBlc3BlY2lmaWNhZGEgY29uY2VkZSDDoCBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPCkNSVVogbyBkaXJlaXRvIGRlIGF1dG9yaXphciBxdWFscXVlciBwZXNzb2Eg4oCTIGbDrXNpY2Egb3UganVyw61kaWNhLCBww7pibGljYSBvdSBwcml2YWRhLCBuYWNpb25hbCBvdQplc3RyYW5nZWlyYSDigJMgYSBhY2Vzc2FyIGUgdXRpbGl6YXIgYW1wbGFtZW50ZSBhIE9CUkEsIHNlbSBleGNsdXNpdmlkYWRlLCBwYXJhIHF1YWlzcXVlcgpmaW5hbGlkYWRlcyBuw6NvIGNvbWVyY2lhaXM7CgooNCkgREVDTEFSQSBxdWUgYSBvYnJhIMOpIGNyaWHDp8OjbyBvcmlnaW5hbCBlIHF1ZSDDqSBvIHRpdHVsYXIgZG9zIGRpcmVpdG9zIGFxdWkgY2VkaWRvcyBlIGF1dG9yaXphZG9zLApyZXNwb25zYWJpbGl6YW5kby1zZSBpbnRlZ3JhbG1lbnRlIHBlbG8gY29udGXDumRvIGUgb3V0cm9zIGVsZW1lbnRvcyBxdWUgZmF6ZW0gcGFydGUgZGEgT0JSQSwKaW5jbHVzaXZlIG9zIGRpcmVpdG9zIGRlIHZveiBlIGltYWdlbSB2aW5jdWxhZG9zIMOgIE9CUkEsIG9icmlnYW5kby1zZSBhIGluZGVuaXphciB0ZXJjZWlyb3MgcG9yCmRhbm9zLCBiZW0gY29tbyBpbmRlbml6YXIgZSByZXNzYXJjaXIgYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVogZGUKZXZlbnR1YWlzIGRlc3Blc2FzIHF1ZSB2aWVyZW0gYSBzdXBvcnRhciwgZW0gcmF6w6NvIGRlIHF1YWxxdWVyIG9mZW5zYSBhIGRpcmVpdG9zIGF1dG9yYWlzIG91CmRpcmVpdG9zIGRlIHZveiBvdSBpbWFnZW0sIHByaW5jaXBhbG1lbnRlIG5vIHF1ZSBkaXogcmVzcGVpdG8gYSBwbMOhZ2lvIGUgdmlvbGHDp8O1ZXMgZGUgZGlyZWl0b3M7CgooNSkgQUZJUk1BIHF1ZSBjb25oZWNlIGEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTwpPU1dBTERPIENSVVogZSBhcyBkaXJldHJpemVzIHBhcmEgbyBmdW5jaW9uYW1lbnRvIGRvIHJlcG9zaXTDs3JpbyBpbnN0aXR1Y2lvbmFsIEFSQ0EuCgpBIFBvbMOtdGljYSBJbnN0aXR1Y2lvbmFsIGRlIEFjZXNzbyBBYmVydG8gZGEgRklPQ1JVWiAtIEZVTkRBw4fDg08gT1NXQUxETyBDUlVaIHJlc2VydmEKZXhjbHVzaXZhbWVudGUgYW8gQVVUT1Igb3MgZGlyZWl0b3MgbW9yYWlzIGUgb3MgdXNvcyBjb21lcmNpYWlzIHNvYnJlIGFzIG9icmFzIGRlIHN1YSBhdXRvcmlhCmUvb3UgdGl0dWxhcmlkYWRlLCBzZW5kbyBvcyB0ZXJjZWlyb3MgdXN1w6FyaW9zIHJlc3BvbnPDoXZlaXMgcGVsYSBhdHJpYnVpw6fDo28gZGUgYXV0b3JpYSBlIG1hbnV0ZW7Dp8OjbwpkYSBpbnRlZ3JpZGFkZSBkYSBPQlJBIGVtIHF1YWxxdWVyIHV0aWxpemHDp8Ojby4KCkEgUG9sw610aWNhIEluc3RpdHVjaW9uYWwgZGUgQWNlc3NvIEFiZXJ0byBkYSBGSU9DUlVaIC0gRlVOREHDh8ODTyBPU1dBTERPIENSVVoKcmVzcGVpdGEgb3MgY29udHJhdG9zIGUgYWNvcmRvcyBwcmVleGlzdGVudGVzIGRvcyBBdXRvcmVzIGNvbSB0ZXJjZWlyb3MsIGNhYmVuZG8gYW9zIEF1dG9yZXMKaW5mb3JtYXIgw6AgSW5zdGl0dWnDp8OjbyBhcyBjb25kacOnw7VlcyBlIG91dHJhcyByZXN0cmnDp8O1ZXMgaW1wb3N0YXMgcG9yIGVzdGVzIGluc3RydW1lbnRvcy4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-11-17T13:26:57Repositório Institucional da FIOCRUZ (ARCA) - 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| dc.title.en_US.fl_str_mv |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| title |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| spellingShingle |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations Zobrist, Stephanie Porto Velho Rondônia Allplex SARS-CoV-2 assay SalivaDirect Teste PADRÃO Q COVID-19 Ag LumiraDx SARS-CoV-2 Ag test Porto Velho Rondônia Allplex SARS-CoV-2 assay SalivaDirect SD Biosensor STANDARD Q COVID-19 Ag LumiraDx SARS-CoV-2 Ag test Porto Velho Rondônia Ensayo Allplex SARS-CoV-2 SalivaDirect SD Biosensor STANDARD Q COVID-19 Ag La Prueba LumiraDx SARS-CoV-2 Ag SARS-CoV-2 COVID-19 Reação em Cadeia da Polimerase Via Transcriptase Reversa Kit de Reagentes para Diagnóstico |
| title_short |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| title_full |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| title_fullStr |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| title_full_unstemmed |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| title_sort |
Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations |
| author |
Zobrist, Stephanie |
| author_facet |
Zobrist, Stephanie Oliveira-Silva, Michelle Vieira, Alexia Martines Bansil, Pooja Gerth-Guyette, Emily Leader, Brandon T. Golden, Allison Slater, Hannah Cruz, Catherine Duran de Lucena Garbin, Eduardo Sagalovsky, Mariana Pal, Sampa Gupta, Vin Wolansky, Leo Dall'Acqua, Deusilene Souza Vieira Naveca, Felipe Gomes Nascimento, Valdinete Alves do Villalobos Salcedo, Juan Miguel Drain, Paul K. Costa, Alexandre Dias Tavares Domingo, Gonzalo J. Pereira, Dhélio |
| author_role |
author |
| author2 |
Oliveira-Silva, Michelle Vieira, Alexia Martines Bansil, Pooja Gerth-Guyette, Emily Leader, Brandon T. Golden, Allison Slater, Hannah Cruz, Catherine Duran de Lucena Garbin, Eduardo Sagalovsky, Mariana Pal, Sampa Gupta, Vin Wolansky, Leo Dall'Acqua, Deusilene Souza Vieira Naveca, Felipe Gomes Nascimento, Valdinete Alves do Villalobos Salcedo, Juan Miguel Drain, Paul K. Costa, Alexandre Dias Tavares Domingo, Gonzalo J. Pereira, Dhélio |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Zobrist, Stephanie Oliveira-Silva, Michelle Vieira, Alexia Martines Bansil, Pooja Gerth-Guyette, Emily Leader, Brandon T. Golden, Allison Slater, Hannah Cruz, Catherine Duran de Lucena Garbin, Eduardo Sagalovsky, Mariana Pal, Sampa Gupta, Vin Wolansky, Leo Dall'Acqua, Deusilene Souza Vieira Naveca, Felipe Gomes Nascimento, Valdinete Alves do Villalobos Salcedo, Juan Miguel Drain, Paul K. Costa, Alexandre Dias Tavares Domingo, Gonzalo J. Pereira, Dhélio |
| dc.subject.other.pt_BR.fl_str_mv |
Porto Velho Rondônia Allplex SARS-CoV-2 assay SalivaDirect Teste PADRÃO Q COVID-19 Ag LumiraDx SARS-CoV-2 Ag test |
| topic |
Porto Velho Rondônia Allplex SARS-CoV-2 assay SalivaDirect Teste PADRÃO Q COVID-19 Ag LumiraDx SARS-CoV-2 Ag test Porto Velho Rondônia Allplex SARS-CoV-2 assay SalivaDirect SD Biosensor STANDARD Q COVID-19 Ag LumiraDx SARS-CoV-2 Ag test Porto Velho Rondônia Ensayo Allplex SARS-CoV-2 SalivaDirect SD Biosensor STANDARD Q COVID-19 Ag La Prueba LumiraDx SARS-CoV-2 Ag SARS-CoV-2 COVID-19 Reação em Cadeia da Polimerase Via Transcriptase Reversa Kit de Reagentes para Diagnóstico |
| dc.subject.en.en_US.fl_str_mv |
Porto Velho Rondônia Allplex SARS-CoV-2 assay SalivaDirect SD Biosensor STANDARD Q COVID-19 Ag LumiraDx SARS-CoV-2 Ag test |
| dc.subject.es.es_ES.fl_str_mv |
Porto Velho Rondônia Ensayo Allplex SARS-CoV-2 SalivaDirect SD Biosensor STANDARD Q COVID-19 Ag La Prueba LumiraDx SARS-CoV-2 Ag |
| dc.subject.decs.pt_BR.fl_str_mv |
SARS-CoV-2 COVID-19 Reação em Cadeia da Polimerase Via Transcriptase Reversa Kit de Reagentes para Diagnóstico |
| description |
Diagnostics - PATH. Seattle, WA, USA. |
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2022 |
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2022-06-20T18:54:40Z |
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2022-06-20T18:54:40Z |
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2022 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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ZOBRIST, Stephanie et al. Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations. The Journal of Infectious Diseases, p. 1-11, 20 May 2022. |
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https://www.arca.fiocruz.br/handle/icict/53379 |
| dc.identifier.issn.pt_BR.fl_str_mv |
0022-1899 |
| dc.identifier.doi.none.fl_str_mv |
10.1093/infdis/jiac204 |
| dc.identifier.eissn.none.fl_str_mv |
1537-6613 |
| identifier_str_mv |
ZOBRIST, Stephanie et al. Screening for severe acute respiratory syndrome coronavirus 2 in close contacts of individuals with confirmed infection: performance and operational considerations. The Journal of Infectious Diseases, p. 1-11, 20 May 2022. 0022-1899 10.1093/infdis/jiac204 1537-6613 |
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https://www.arca.fiocruz.br/handle/icict/53379 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Oxford University Press |
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Oxford University Press |
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