Therapy for ocular toxoplasmosis
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/37117 |
Resumo: | 2020-11-18 |
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De-La-Torre, AlejandraStanford, MilesCuri, AndréJaffe, Glenn J.Gomez-Marin, Jorge E.2019-11-18T14:34:02Z2019-11-18T14:34:02Z2011DE-LA-TORRE, Alejandra et al. Therapy for ocular toxoplasmosis. Ocular Immunology and Inflammation, v. 19, n. 5, p. 314-320, 2011.0927-3948https://www.arca.fiocruz.br/handle/icict/3711710.3109/09273948.2011.6089151678-8060engTaylor & FrancisTherapy for ocular toxoplasmosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-11-18Universidad del Quindío. Centro de Investigaciones Biomédicas. Grupo de Estudio en Parasitología Molecular. Armenia, Colombia.King’s College London. St. Thomas’ Campus. Rayne Institute, Department of Academic Ophthalmology. London, UK.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Duke Eye Center. Duke Reading Center. Durham, NC, USA.Universidad del Quindío. Centro de Investigaciones Biomédicas. Grupo de Estudio en Parasitología Molecular. Armenia, Colombia.Purpose: To review current evidence for the treatment of ocular toxoplasmosis (OT). Design: Narrative review and expert recommendations. Methods: Meta-analysis and selected original articles from the medical literature were reviewed critically. Expert recommendations were analyzed. Results: Numerous observational studies suggest a benefit of short-term antimicrobial therapy for toxoplasmic retinochoroiditis in immunocompetent patients, although its efficacy has not been proven in randomized clinical trials. A randomized clinical trial revealed that intermittent trimethoprim/sulfamethoxazole treatment could decrease the rate of recurrence in high-risk patients. Intravitreal injection of clindamycin and dexamethasone was an acceptable alternative to the classic treatment for OT in a randomized clinical trial. Conclusions: Opinions about therapy differ and controversy remains about its type, efficacy, and length. Intravitreal therapy may be promising for OT. A recent description of the presence of parasitemia in patients with active and inactive ocular toxoplasmosis raises new questions that need to be explored.AntibioticsOcular toxoplasmosisRecurrencesSteroidsTherapyTreatmentUveitisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/37117/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_De-La-Torre_Alejandra_etal INI_2011.pdfve_De-La-Torre_Alejandra_etal INI_2011.pdfapplication/pdf716556https://www.arca.fiocruz.br/bitstream/icict/37117/2/ve_De-La-Torre_Alejandra_etal%20INI_2011.pdf40401d3c7d7f66a2073c0c510bb6f1b8MD52TEXTve_De-La-Torre_Alejandra_etal INI_2011.pdf.txtve_De-La-Torre_Alejandra_etal INI_2011.pdf.txtExtracted texttext/plain39596https://www.arca.fiocruz.br/bitstream/icict/37117/3/ve_De-La-Torre_Alejandra_etal%20INI_2011.pdf.txtbaacd3fc93a659385f619fbb755701fdMD53icict/371172021-03-24 16:32:39.363oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:39Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Therapy for ocular toxoplasmosis |
title |
Therapy for ocular toxoplasmosis |
spellingShingle |
Therapy for ocular toxoplasmosis De-La-Torre, Alejandra Antibiotics Ocular toxoplasmosis Recurrences Steroids Therapy Treatment Uveitis |
title_short |
Therapy for ocular toxoplasmosis |
title_full |
Therapy for ocular toxoplasmosis |
title_fullStr |
Therapy for ocular toxoplasmosis |
title_full_unstemmed |
Therapy for ocular toxoplasmosis |
title_sort |
Therapy for ocular toxoplasmosis |
author |
De-La-Torre, Alejandra |
author_facet |
De-La-Torre, Alejandra Stanford, Miles Curi, André Jaffe, Glenn J. Gomez-Marin, Jorge E. |
author_role |
author |
author2 |
Stanford, Miles Curi, André Jaffe, Glenn J. Gomez-Marin, Jorge E. |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
De-La-Torre, Alejandra Stanford, Miles Curi, André Jaffe, Glenn J. Gomez-Marin, Jorge E. |
dc.subject.en.pt_BR.fl_str_mv |
Antibiotics Ocular toxoplasmosis Recurrences Steroids Therapy Treatment Uveitis |
topic |
Antibiotics Ocular toxoplasmosis Recurrences Steroids Therapy Treatment Uveitis |
description |
2020-11-18 |
publishDate |
2011 |
dc.date.issued.fl_str_mv |
2011 |
dc.date.accessioned.fl_str_mv |
2019-11-18T14:34:02Z |
dc.date.available.fl_str_mv |
2019-11-18T14:34:02Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
DE-LA-TORRE, Alejandra et al. Therapy for ocular toxoplasmosis. Ocular Immunology and Inflammation, v. 19, n. 5, p. 314-320, 2011. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/37117 |
dc.identifier.issn.pt_BR.fl_str_mv |
0927-3948 |
dc.identifier.doi.none.fl_str_mv |
10.3109/09273948.2011.608915 |
dc.identifier.eissn.none.fl_str_mv |
1678-8060 |
identifier_str_mv |
DE-LA-TORRE, Alejandra et al. Therapy for ocular toxoplasmosis. Ocular Immunology and Inflammation, v. 19, n. 5, p. 314-320, 2011. 0927-3948 10.3109/09273948.2011.608915 1678-8060 |
url |
https://www.arca.fiocruz.br/handle/icict/37117 |
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eng |
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eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Taylor & Francis |
publisher.none.fl_str_mv |
Taylor & Francis |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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