Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/57484 |
Resumo: | Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil. |
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Saraiva, Roberto M.Mediano, Mauro Felippe F.Mendes, Fernanda S. N. S.Silva, Gilberto Marcelo Sperandio daVeloso, Henrique H.Sangenis, Luiz Henrique C.Silva, Paula Simplício daMazzoli-Rocha, FlaviaSousa, Andréa S.Holanda, Marcelo T.Hasslocher-Moreno, Alejandro Marcel2023-03-21T16:19:43Z2023-03-21T16:19:43Z2021-12-26SARAIVA, Roberto M. et al. Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care, World Journal of Cardiology, v. 13, n. 12, p. 654-675, 2021.1949-8462https://www.arca.fiocruz.br/handle/icict/57484engSIRPDoença de ChagasDiagnósticoTratamentoInsuficiência cardíacaArritmiaAVCChagas diseaseDiagnosisTreatmentHeart failureArrhythmiaStrokeChagas heart disease: an overview of diagnosis, manifestations, treatment, and careinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil.Chagas heart disease (CHD) affects approximately 30% of patients chronically infected with the protozoa Trypanosoma cruzi. CHD is classified into four stages of increasing severity according to electrocardiographic, echocardiographic, and clinical criteria. CHD presents with a myriad of clinical manifestations, but its main complications are sudden cardiac death, heart failure, and stroke. Importantly, CHD has a higher incidence of sudden cardiac death and stroke than most other cardiopathies, and patients with CHD complicated by heart failure have a higher mortality than patients with heart failure caused by other etiologies. Among patients with CHD, approximately 90% of deaths can be attributed to complications of Chagas disease. Sudden cardiac death is the most common cause of death (55%–60%), followed by heart failure (25%–30%) and stroke (10%–15%). The high morbimortality and the unique characteristics of CHD demand an individualized approach according to the stage of the disease and associated complications the patient presents with. Therefore, the management of CHD is challenging, and in this review, we present the most updated available data to help clinicians and cardiologists in the care of these patients. We describe the clinical manifestations, diagnosis and classification criteria, risk stratification, and approach to the different clinical aspects of CHD using diagnostic tools and pharmacological and non-pharmacological treatments.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALve_Saraiva_Roberto_etal_INI_2021.pdfve_Saraiva_Roberto_etal_INI_2021.pdfapplication/pdf2543646https://www.arca.fiocruz.br/bitstream/icict/57484/2/ve_Saraiva_Roberto_etal_INI_2021.pdf8deb098a9a020feaf204904992bdfa62MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/57484/1/license.txt5a560609d32a3863062d77ff32785d58MD51icict/574842023-05-09 11:15:18.788oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-05-09T14:15:18Repositório Institucional da FIOCRUZ (ARCA) - 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| dc.title.en_US.fl_str_mv |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| title |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| spellingShingle |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care Saraiva, Roberto M. Doença de Chagas Diagnóstico Tratamento Insuficiência cardíaca Arritmia AVC Chagas disease Diagnosis Treatment Heart failure Arrhythmia Stroke |
| title_short |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| title_full |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| title_fullStr |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| title_full_unstemmed |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| title_sort |
Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care |
| author |
Saraiva, Roberto M. |
| author_facet |
Saraiva, Roberto M. Mediano, Mauro Felippe F. Mendes, Fernanda S. N. S. Silva, Gilberto Marcelo Sperandio da Veloso, Henrique H. Sangenis, Luiz Henrique C. Silva, Paula Simplício da Mazzoli-Rocha, Flavia Sousa, Andréa S. Holanda, Marcelo T. Hasslocher-Moreno, Alejandro Marcel |
| author_role |
author |
| author2 |
Mediano, Mauro Felippe F. Mendes, Fernanda S. N. S. Silva, Gilberto Marcelo Sperandio da Veloso, Henrique H. Sangenis, Luiz Henrique C. Silva, Paula Simplício da Mazzoli-Rocha, Flavia Sousa, Andréa S. Holanda, Marcelo T. Hasslocher-Moreno, Alejandro Marcel |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Saraiva, Roberto M. Mediano, Mauro Felippe F. Mendes, Fernanda S. N. S. Silva, Gilberto Marcelo Sperandio da Veloso, Henrique H. Sangenis, Luiz Henrique C. Silva, Paula Simplício da Mazzoli-Rocha, Flavia Sousa, Andréa S. Holanda, Marcelo T. Hasslocher-Moreno, Alejandro Marcel |
| dc.subject.other.en_US.fl_str_mv |
Doença de Chagas Diagnóstico Tratamento Insuficiência cardíaca Arritmia AVC |
| topic |
Doença de Chagas Diagnóstico Tratamento Insuficiência cardíaca Arritmia AVC Chagas disease Diagnosis Treatment Heart failure Arrhythmia Stroke |
| dc.subject.en.en_US.fl_str_mv |
Chagas disease Diagnosis Treatment Heart failure Arrhythmia Stroke |
| description |
Fundação Oswaldo Cruz. Evandro Chagas National Institute of Infectious Diseases. Rio de Janeiro, RJ, Brasil. |
| publishDate |
2021 |
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2021-12-26 |
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2023-03-21T16:19:43Z |
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2023-03-21T16:19:43Z |
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SARAIVA, Roberto M. et al. Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care, World Journal of Cardiology, v. 13, n. 12, p. 654-675, 2021. |
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https://www.arca.fiocruz.br/handle/icict/57484 |
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1949-8462 |
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SARAIVA, Roberto M. et al. Chagas heart disease: an overview of diagnosis, manifestations, treatment, and care, World Journal of Cardiology, v. 13, n. 12, p. 654-675, 2021. 1949-8462 |
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