Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2012 |
| Outros Autores: | , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/36600 |
Resumo: | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Universidade Nilton Lins. Manaus, AM, Brasil. |
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Lacerda, Marcus V. G.Mourao, Maria P. G.Alexandre, Márcia A. A.Siqueira, André M.Magalhaes, Belisa M. L.Martinez-Espinosa, Flor E.Santana Filho, Franklin S.Brasil, PatríciaVentura, Ana M .R. S.Tada, Mauro S.Couto, Vanja S. C. D.Silva, Antônio R.Silva, Rita S. U.Alecrim, Maria G. C2019-10-21T14:15:05Z2019-10-21T14:15:05Z2012LACERDA, Marcus V. G. et al. Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature. Malaria Journal, v. 11, p. 1-18, 2012.1475-2875https://www.arca.fiocruz.br/handle/icict/3660010.1186/1475-2875-11-121475-2875engBMCUnderstanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literatureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Universidade Nilton Lins. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Universidade Nilton Lins. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Universidade Nilton Lins. Manaus, AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus AM, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Instituto Evandro Chagas. Ananindeua, PA, Brasil.Instituto de Pesquisas em Patologias Tropicais. Porto Velho, RO, Brasil.Secretaria de Saúde do Amapá. Macapá, AP, Brasil.Universidade Federal do Maranhão. São Luiz, MA, Brasil.Universidade Federal do Acre. Rio Branco, AC, Brasil.Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Universidade Nilton Lins. Manaus, AM, Brasil.The resurgence of the malaria eradication agenda and the increasing number of severe manifestation reports has contributed to a renewed interested in the Plasmodium vivax infection. It is the most geographically widespread parasite causing human malaria, with around 2.85 billion people living under risk of infection. The Brazilian Amazon region reports more than 50% of the malaria cases in Latin America and since 1990 there is a marked predominance of this species, responsible for 85% of cases in 2009. However, only a few complicated cases of P. vivax have been reported from this region. A systematic review of the Brazilian indexed and non-indexed literature on complicated cases of vivax malaria was performed including published articles, masters’ dissertations, doctoral theses and national congresses’ abstracts. The following information was retrieved: patient characteristics (demographic, presence of co-morbidities and, whenever possible, associated genetic disorders); description of each major clinical manifestation. As a result, 27 articles, 28 abstracts from scientific events’ annals and 13 theses/dissertations were found, only after 1987. Most of the reported information was described in small case series and case reports of patients from all the Amazonian states, and also in travellers from Brazilian non-endemic areas. The more relevant clinical complications were anaemia, thrombocytopaenia, jaundice and acute respiratory distress syndrome, present in all age groups, in addition to other more rare clinical pictures. Complications in pregnant women were also reported. Acute and chronic co-morbidities were frequent, however death was occasional. Clinical atypical cases of malaria are more frequent than published in the indexed literature, probably due to a publication bias. In the Brazilian Amazon (considered to be a low to moderate intensity area of transmission), clinical data are in accordance with the recent findings of severity described in diverse P. vivax endemic areas (especially anaemia in Southeast Asia), however in this region both children and adults are affected. Finally, gaps of knowledge and areas for future research are opportunely pointed out.MalariaPlasmodium vivaxBrazilSeverityClinical aspectsAnaemiaSystematic reviewinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36600/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Lacerda_Marcus_etal_INI_2012.pdfve_Lacerda_Marcus_etal_INI_2012.pdfapplication/pdf396889https://www.arca.fiocruz.br/bitstream/icict/36600/2/ve_Lacerda_Marcus_etal_INI_2012.pdf917e5ab9f30fb8fbf1cf299025a75b8dMD52TEXTve_Lacerda_Marcus_etal_INI_2012.pdf.txtve_Lacerda_Marcus_etal_INI_2012.pdf.txtExtracted texttext/plain98804https://www.arca.fiocruz.br/bitstream/icict/36600/3/ve_Lacerda_Marcus_etal_INI_2012.pdf.txt60d03877edd45ed01f35938ac94572c8MD53icict/366002019-10-22 02:01:49.657oai:www.arca.fiocruz.br:icict/36600Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-10-22T05:01:49Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| title |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| spellingShingle |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature Lacerda, Marcus V. G. Malaria Plasmodium vivax Brazil Severity Clinical aspects Anaemia Systematic review |
| title_short |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| title_full |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| title_fullStr |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| title_full_unstemmed |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| title_sort |
Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature |
| author |
Lacerda, Marcus V. G. |
| author_facet |
Lacerda, Marcus V. G. Mourao, Maria P. G. Alexandre, Márcia A. A. Siqueira, André M. Magalhaes, Belisa M. L. Martinez-Espinosa, Flor E. Santana Filho, Franklin S. Brasil, Patrícia Ventura, Ana M .R. S. Tada, Mauro S. Couto, Vanja S. C. D. Silva, Antônio R. Silva, Rita S. U. Alecrim, Maria G. C |
| author_role |
author |
| author2 |
Mourao, Maria P. G. Alexandre, Márcia A. A. Siqueira, André M. Magalhaes, Belisa M. L. Martinez-Espinosa, Flor E. Santana Filho, Franklin S. Brasil, Patrícia Ventura, Ana M .R. S. Tada, Mauro S. Couto, Vanja S. C. D. Silva, Antônio R. Silva, Rita S. U. Alecrim, Maria G. C |
| author2_role |
author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Lacerda, Marcus V. G. Mourao, Maria P. G. Alexandre, Márcia A. A. Siqueira, André M. Magalhaes, Belisa M. L. Martinez-Espinosa, Flor E. Santana Filho, Franklin S. Brasil, Patrícia Ventura, Ana M .R. S. Tada, Mauro S. Couto, Vanja S. C. D. Silva, Antônio R. Silva, Rita S. U. Alecrim, Maria G. C |
| dc.subject.en.pt_BR.fl_str_mv |
Malaria Plasmodium vivax Brazil Severity Clinical aspects Anaemia Systematic review |
| topic |
Malaria Plasmodium vivax Brazil Severity Clinical aspects Anaemia Systematic review |
| description |
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado. Manaus, AM, Brazil / Universidade do Estado do Amazonas. Manaus AM, Brasil / Universidade Nilton Lins. Manaus, AM, Brasil. |
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2012 |
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2012 |
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2019-10-21T14:15:05Z |
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2019-10-21T14:15:05Z |
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LACERDA, Marcus V. G. et al. Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature. Malaria Journal, v. 11, p. 1-18, 2012. |
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https://www.arca.fiocruz.br/handle/icict/36600 |
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10.1186/1475-2875-11-12 |
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1475-2875 |
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LACERDA, Marcus V. G. et al. Understanding the clinical spectrum of complicated Plasmodium vivax malaria: a systematic review on the contributions of the Brazilian literature. Malaria Journal, v. 11, p. 1-18, 2012. 1475-2875 10.1186/1475-2875-11-12 |
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