Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study

Detalhes bibliográficos
Autor(a) principal: Teodoro, Renata Pereira
Data de Publicação: 2021
Outros Autores: Scherer, Danielle, Camargo, Maria José de, Costa, Ana Carolina Carioca da, Andrade, Cecília Vianna de, Russomano, Fábio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/50604
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.
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spelling Teodoro, Renata PereiraScherer, DanielleCamargo, Maria José deCosta, Ana Carolina Carioca daAndrade, Cecília Vianna deRussomano, Fábio2022-01-03T18:36:49Z2022-01-03T18:36:49Z2021TEODORO, Renata Pereira et al. Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study. BMC Women's Health, v. 21, n. 400, p. 1-5, 7 Dec. 2021.1472-6874https://www.arca.fiocruz.br/handle/icict/5060410.1186/s12905-021-01552-61472-6874engBMCNegative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.Background: According to the Brazilian Guidelines on Cervical Cancer Screening, women with cytopathologic diagnosis of high-grade intraepithelial lesion, abnormal colposcopic findings, fully visible squamocolumnar junction and age 25 years or older should be treated at the first visit ("see and treat-S&T"). The main limitation to this approach is the risk of overtreatment, identified by histology without preinvasive lesion. The objectives of this study were to identify the overtreatment rate in women undergoing S&T in cervical cancer prevention at a referral center with extensive experience with the method and to detect possible factors associated with this rate. Methods: This was a cross-sectional study that analyzed records from a database with 616 women submitted to S&T from 1996 to 2017. Negative histology was defined as the following histopathologic results: human papillomavirus without cervical intraepithelial neoplasia (CIN), inflammatory, low-grade squamous intraepithelial lesion, and CIN 1. Results: Of the 616 women, there were 52 (8.44%, 95%CI 6.25-10.64%) with a histopathologic report without preinvasive cervical lesion. No statistical association was found between this outcome and age or a significant downward trend over time. Conclusion: The overtreatment rate in this study can be considered low and consistent with the acceptable rates reported in the literature, reinforcing the prevailing Brazilian guideline, in which the benefits of immediate treatment outweigh the risk of losses following biopsy.Cervical intraepithelial neoplasiaColposcopyOvertreatmentNegative histologyRio de JaneiroBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83132https://www.arca.fiocruz.br/bitstream/icict/50604/1/license.txt33967fcc8ef681b8f5c2c34178ebc114MD51ORIGINALve_Renata_Teodoro_etal_IFF_2021.pdfve_Renata_Teodoro_etal_IFF_2021.pdfapplication/pdf756003https://www.arca.fiocruz.br/bitstream/icict/50604/2/ve_Renata_Teodoro_etal_IFF_2021.pdf7ab2c07a51b9baf485895ceed31c7636MD52icict/506042022-01-25 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dc.title.en_US.fl_str_mv Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
title Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
spellingShingle Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
Teodoro, Renata Pereira
Cervical intraepithelial neoplasia
Colposcopy
Overtreatment
Negative histology
Rio de Janeiro
Brazil
title_short Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
title_full Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
title_fullStr Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
title_full_unstemmed Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
title_sort Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study
author Teodoro, Renata Pereira
author_facet Teodoro, Renata Pereira
Scherer, Danielle
Camargo, Maria José de
Costa, Ana Carolina Carioca da
Andrade, Cecília Vianna de
Russomano, Fábio
author_role author
author2 Scherer, Danielle
Camargo, Maria José de
Costa, Ana Carolina Carioca da
Andrade, Cecília Vianna de
Russomano, Fábio
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Teodoro, Renata Pereira
Scherer, Danielle
Camargo, Maria José de
Costa, Ana Carolina Carioca da
Andrade, Cecília Vianna de
Russomano, Fábio
dc.subject.en.en_US.fl_str_mv Cervical intraepithelial neoplasia
Colposcopy
Overtreatment
Negative histology
Rio de Janeiro
Brazil
topic Cervical intraepithelial neoplasia
Colposcopy
Overtreatment
Negative histology
Rio de Janeiro
Brazil
description Fundação Oswaldo Cruz. Instituto Nacional de Saúde da Mulher, da Criança e do Adolescente Fernandes Figueira. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2022-01-03T18:36:49Z
dc.date.available.fl_str_mv 2022-01-03T18:36:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TEODORO, Renata Pereira et al. Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study. BMC Women's Health, v. 21, n. 400, p. 1-5, 7 Dec. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/50604
dc.identifier.issn.pt_BR.fl_str_mv 1472-6874
dc.identifier.doi.pt_BR.fl_str_mv 10.1186/s12905-021-01552-6
dc.identifier.eissn.pt_BR.fl_str_mv 1472-6874
identifier_str_mv TEODORO, Renata Pereira et al. Negative histology in cervical specimens obtained with the "see and treat" method among women at a referral center in Rio de Janeiro, Brazil: a cross-sectional study. BMC Women's Health, v. 21, n. 400, p. 1-5, 7 Dec. 2021.
1472-6874
10.1186/s12905-021-01552-6
url https://www.arca.fiocruz.br/handle/icict/50604
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/50604/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/50604/2/ve_Renata_Teodoro_etal_IFF_2021.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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