Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.

Detalhes bibliográficos
Autor(a) principal: Tartof, Sara Yee
Data de Publicação: 2010
Outros Autores: Reis, Joice Neves, Andrade, Aurelio Nei, Ramos, Regina Terse Trindade, Reis, Mitermayer Galvão dos, Riley, Lee Woodland
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7504
Resumo: University of California Berkeley. School of Public Health. USA.
id CRUZ_bd28336daeef3a3e376ab7faf35cb6c9
oai_identifier_str oai:www.arca.fiocruz.br:icict/7504
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Tartof, Sara YeeReis, Joice NevesAndrade, Aurelio NeiRamos, Regina Terse TrindadeReis, Mitermayer Galvão dosRiley, Lee Woodland2014-04-08T16:31:04Z2014-04-08T16:31:04Z2010TARTOF, S. Y. et al. Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study. BMC Infectious Diseases, v. 10, p. 327, 2010.1471-2334https://www.arca.fiocruz.br/handle/icict/7504engBioMed CentralFactors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity of California Berkeley. School of Public Health. USA.Universidade Federal da Bahia. Faculdade de Farmácia. Salvador, BA, BrasilHospital São Rafael-Monte Tabor. Salvador, BA, BrasilFederal University of Bahia School of Medicine. Department of Pediatrics. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, BrasilUniversity of California Berkeley. School of Public Health. USA.Group A Streptococcus (GAS) strain diversity varies across different regions of the world, according to low versus high-income countries. These differences may be related to geographic, environmental, socioeconomic, or host-related factors. However, local factors may also affect strain diversity. We compared the emm types of GAS isolates from children with and without sore throat in one large urban setting in Brazil. METHODS: Children 3-15 years of age were consecutively recruited from slum and non-slum pediatric outpatient clinics between April-October, 2008. Throat cultures were performed and data intake forms were completed. GAS isolates were typed by emm sequencing. RESULTS: From 2194 children, 254 (12%) GAS isolates were obtained. Of 238 GAS isolates that were emm-typed, 61 unique emm types were identified. Simpson's diversity index of the emm types was higher among isolates from slum children [97% (96%-98%)] than those of non-slum children [92% (89%-96%)]. Two emm types (66.0, 12.0) were more frequently isolated from children with sore throat (p < 0.05), and one emm type (27G.0) demonstrated a protective effect. CONCLUSIONS: The emm type diversity from children attending slum clinics resembled the emm diversity of low income countries rather than that of children attending a non-slum clinic in the same city. Local factors, such as crowding, may enhance the frequency of GAS transmission and horizontal gene transfers that contribute to increased strain diversity in the slums. GAS vaccine coverage and control of GAS infections will need to take these local factors and strain differences into consideration.Variação GenéticaInfecções Estreptocócicas/epidemiologiaStreptococcus pyogenes/genéticaAdolescenteTécnicas de Tipagem BacterianaBrasil/epidemiologiaCriançaPré-EscolarEstudos TransversaisFemininoGenótipoHumanosMasculinoFaringiteÁreas de PobrezaInfecções Estreptocócicas/microbiologiaStreptococcus pyogenes/classificaçãoStreptococcus pyogenes/isolamento & purificaçãoPopulação Urbanainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALTartof S Y Factors....pdfTartof S Y Factors....pdfapplication/pdf378389https://www.arca.fiocruz.br/bitstream/icict/7504/1/Tartof%20S%20Y%20Factors....pdf6ed0d42b207c2ade1b92b32bebe7f76bMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7504/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTTartof S Y Factors....pdf.txtTartof S Y Factors....pdf.txtExtracted texttext/plain32839https://www.arca.fiocruz.br/bitstream/icict/7504/5/Tartof%20S%20Y%20Factors....pdf.txt8e1f4eb7e006532da0fc6f67a4fe313bMD55THUMBNAILTartof S Y Factors....pdf.jpgTartof S Y Factors....pdf.jpgGenerated Thumbnailimage/jpeg2365https://www.arca.fiocruz.br/bitstream/icict/7504/4/Tartof%20S%20Y%20Factors....pdf.jpg7b95fc95c22847f0e75ce66f77fadd2dMD54icict/75042023-03-15 14:33:07.622oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:07Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
title Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
spellingShingle Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
Tartof, Sara Yee
Variação Genética
Infecções Estreptocócicas/epidemiologia
Streptococcus pyogenes/genética
Adolescente
Técnicas de Tipagem Bacteriana
Brasil/epidemiologia
Criança
Pré-Escolar
Estudos Transversais
Feminino
Genótipo
Humanos
Masculino
Faringite
Áreas de Pobreza
Infecções Estreptocócicas/microbiologia
Streptococcus pyogenes/classificação
Streptococcus pyogenes/isolamento & purificação
População Urbana
title_short Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
title_full Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
title_fullStr Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
title_full_unstemmed Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
title_sort Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study.
author Tartof, Sara Yee
author_facet Tartof, Sara Yee
Reis, Joice Neves
Andrade, Aurelio Nei
Ramos, Regina Terse Trindade
Reis, Mitermayer Galvão dos
Riley, Lee Woodland
author_role author
author2 Reis, Joice Neves
Andrade, Aurelio Nei
Ramos, Regina Terse Trindade
Reis, Mitermayer Galvão dos
Riley, Lee Woodland
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Tartof, Sara Yee
Reis, Joice Neves
Andrade, Aurelio Nei
Ramos, Regina Terse Trindade
Reis, Mitermayer Galvão dos
Riley, Lee Woodland
dc.subject.decs.pt_BR.fl_str_mv Variação Genética
Infecções Estreptocócicas/epidemiologia
Streptococcus pyogenes/genética
Adolescente
Técnicas de Tipagem Bacteriana
Brasil/epidemiologia
Criança
Pré-Escolar
Estudos Transversais
Feminino
Genótipo
Humanos
Masculino
Faringite
Áreas de Pobreza
Infecções Estreptocócicas/microbiologia
Streptococcus pyogenes/classificação
Streptococcus pyogenes/isolamento & purificação
População Urbana
topic Variação Genética
Infecções Estreptocócicas/epidemiologia
Streptococcus pyogenes/genética
Adolescente
Técnicas de Tipagem Bacteriana
Brasil/epidemiologia
Criança
Pré-Escolar
Estudos Transversais
Feminino
Genótipo
Humanos
Masculino
Faringite
Áreas de Pobreza
Infecções Estreptocócicas/microbiologia
Streptococcus pyogenes/classificação
Streptococcus pyogenes/isolamento & purificação
População Urbana
description University of California Berkeley. School of Public Health. USA.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2014-04-08T16:31:04Z
dc.date.available.fl_str_mv 2014-04-08T16:31:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TARTOF, S. Y. et al. Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study. BMC Infectious Diseases, v. 10, p. 327, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7504
dc.identifier.issn.none.fl_str_mv 1471-2334
identifier_str_mv TARTOF, S. Y. et al. Factors associated with Group A Streptococcus emm type diversification in a large urban setting in Brazil: a cross-sectional study. BMC Infectious Diseases, v. 10, p. 327, 2010.
1471-2334
url https://www.arca.fiocruz.br/handle/icict/7504
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/7504/1/Tartof%20S%20Y%20Factors....pdf
https://www.arca.fiocruz.br/bitstream/icict/7504/2/license.txt
https://www.arca.fiocruz.br/bitstream/icict/7504/5/Tartof%20S%20Y%20Factors....pdf.txt
https://www.arca.fiocruz.br/bitstream/icict/7504/4/Tartof%20S%20Y%20Factors....pdf.jpg
bitstream.checksum.fl_str_mv 6ed0d42b207c2ade1b92b32bebe7f76b
7d48279ffeed55da8dfe2f8e81f3b81f
8e1f4eb7e006532da0fc6f67a4fe313b
7b95fc95c22847f0e75ce66f77fadd2d
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1822791811880452096

Registros relacionados