Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum

Detalhes bibliográficos
Autor(a) principal: Gonçalves, Daniela da Silva
Data de Publicação: 2019
Outros Autores: Iturbe-Ormaetxe, Iñaki, Silva, Andrea Martins da, Telleria, Erich Loza, Rocha, Marcele Neves, Traub-Csekö, Yara M., O'Neill, Scott L., Sant'Anna, Maurício Roberto Viana, Moreira, Luciano Andrade
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31966
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno Vetor. Belo Horizonte, MG, Brasil.
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spelling Gonçalves, Daniela da SilvaIturbe-Ormaetxe, IñakiSilva, Andrea Martins daTelleria, Erich LozaRocha, Marcele NevesTraub-Csekö, Yara M.O'Neill, Scott L.Sant'Anna, Maurício Roberto VianaMoreira, Luciano Andrade2019-03-07T13:32:11Z2019-03-07T13:32:11Z2019GONÇALVES, Daniela da Silva et al. Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum. Parasites & Vectors, v. 12, n. 33, p. 1-13, 2019.1756-3305https://www.arca.fiocruz.br/handle/icict/3196610.1186/s13071-018-3227-4engBMCWolbachiaLutzomyia longipalpisLeishmania infantumWolbachiaLutzomyia longipalpisLulo cellLL-5 cellLeishmania infantumWolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantuminfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno Vetor. Belo Horizonte, MG, Brasil.Monash University. Institute of Vector-Borne Disease. World Mosquito Program. Clayton, Australia.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno Vetor. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Parasitos e Vetores. Rio de Janeiro, RJ. Brasil.Monash University. Institute of Vector-Borne Disease. World Mosquito Program. Clayton, Australia.Universidade Federal de Minas Gerais. Departamento de Parasitologia. Laboratório de Insetos Hematófagos. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno Vetor. Belo Horizonte, MG, Brasil.The leishmaniases are important neglected diseases caused by Leishmania spp. which are transmitted by sand flies, Lutzomyia longipalpis being the main vector of visceral leishmaniasis in the Americas. The methodologies for leishmaniasis control are not efficient, causing 1.5 million reported cases annually worldwide, therefore showing the need for development of novel strategies and interventions to control transmission of the disease. The bacterium Wolbachia pipientis is being used to control viruses transmitted by mosquitoes, such as dengue and Zika, and its introduction in disease vectors has been effective against parasites such as Plasmodium. Here we show the first successful establishment of Wolbachia into two different embryonic cell lines from L. longipalpis, LL-5 and Lulo, and analysed its effects on the sand fly innate immune system, followed by in vitro Leishmania infantum interaction.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31966/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALandreamsilva-erichtelleria_etal_IOC_2019.pdfandreamsilva-erichtelleria_etal_IOC_2019.pdfapplication/pdf1755206https://www.arca.fiocruz.br/bitstream/icict/31966/2/andreamsilva-erichtelleria_etal_IOC_2019.pdf9514e4a836a3a6bdd260b12216dde9b2MD52TEXTandreamsilva-erichtelleria_etal_IOC_2019.pdf.txtandreamsilva-erichtelleria_etal_IOC_2019.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
title Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
spellingShingle Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
Gonçalves, Daniela da Silva
Wolbachia
Lutzomyia longipalpis
Leishmania infantum
Wolbachia
Lutzomyia longipalpis
Lulo cell
LL-5 cell
Leishmania infantum
title_short Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
title_full Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
title_fullStr Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
title_full_unstemmed Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
title_sort Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum
author Gonçalves, Daniela da Silva
author_facet Gonçalves, Daniela da Silva
Iturbe-Ormaetxe, Iñaki
Silva, Andrea Martins da
Telleria, Erich Loza
Rocha, Marcele Neves
Traub-Csekö, Yara M.
O'Neill, Scott L.
Sant'Anna, Maurício Roberto Viana
Moreira, Luciano Andrade
author_role author
author2 Iturbe-Ormaetxe, Iñaki
Silva, Andrea Martins da
Telleria, Erich Loza
Rocha, Marcele Neves
Traub-Csekö, Yara M.
O'Neill, Scott L.
Sant'Anna, Maurício Roberto Viana
Moreira, Luciano Andrade
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gonçalves, Daniela da Silva
Iturbe-Ormaetxe, Iñaki
Silva, Andrea Martins da
Telleria, Erich Loza
Rocha, Marcele Neves
Traub-Csekö, Yara M.
O'Neill, Scott L.
Sant'Anna, Maurício Roberto Viana
Moreira, Luciano Andrade
dc.subject.other.pt_BR.fl_str_mv Wolbachia
Lutzomyia longipalpis
Leishmania infantum
topic Wolbachia
Lutzomyia longipalpis
Leishmania infantum
Wolbachia
Lutzomyia longipalpis
Lulo cell
LL-5 cell
Leishmania infantum
dc.subject.en.pt_BR.fl_str_mv Wolbachia
Lutzomyia longipalpis
Lulo cell
LL-5 cell
Leishmania infantum
description Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Grupo Mosquitos Vetores: Endossimbiontes e Interação Patógeno Vetor. Belo Horizonte, MG, Brasil.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-03-07T13:32:11Z
dc.date.available.fl_str_mv 2019-03-07T13:32:11Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv GONÇALVES, Daniela da Silva et al. Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum. Parasites & Vectors, v. 12, n. 33, p. 1-13, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31966
dc.identifier.issn.pt_BR.fl_str_mv 1756-3305
dc.identifier.doi.none.fl_str_mv 10.1186/s13071-018-3227-4
identifier_str_mv GONÇALVES, Daniela da Silva et al. Wolbachia introduction into Lutzomyia longipalpis (Diptera: Psychodidae) cell lines and its effects on immune-related gene expression and interaction with Leishmania infantum. Parasites & Vectors, v. 12, n. 33, p. 1-13, 2019.
1756-3305
10.1186/s13071-018-3227-4
url https://www.arca.fiocruz.br/handle/icict/31966
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BMC
publisher.none.fl_str_mv BMC
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
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