Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology

Detalhes bibliográficos
Autor(a) principal: Almeida, Márcia R.
Data de Publicação: 2010
Outros Autores: Leitão, Gilda G., Silva, Bárbara V., Barbosa, Jussara P., Pinto, Angelo C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/25720
Resumo: A rapid and efficient method, using high-speed counter-current chromatography (HSCCC) technique, was developed for the separation of isomeric isatin derivatives, prepared following the Sandmeyer route. The biphasic solvent system composed of hexane:ethyl acetate:ethanol:water 1:0.5:0.5:1 (v/v/v/v) was used for all separations.
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spelling Almeida, Márcia R.Leitão, Gilda G.Silva, Bárbara V.Barbosa, Jussara P.Pinto, Angelo C.2018-04-10T13:55:31Z2018-04-10T13:55:31Z2010ALMEIDA, Márcia R. et al. Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology. J. Braz. Chem. Soc., v.21, n.4, p.764-769, 2010.0103-5053https://www.arca.fiocruz.br/handle/icict/257201678-4790A rapid and efficient method, using high-speed counter-current chromatography (HSCCC) technique, was developed for the separation of isomeric isatin derivatives, prepared following the Sandmeyer route. The biphasic solvent system composed of hexane:ethyl acetate:ethanol:water 1:0.5:0.5:1 (v/v/v/v) was used for all separations.A rapid and efficient method, using high-speed counter-current chromatography (HSCCC) technique, was developed for the separation of isomeric isatin derivatives, prepared following the Sandmeyer route. The biphasic solvent system composed of hexane:ethyl acetate:ethanol:water 1:0.5:0.5:1 (v/v/v/v) was used for all separations.Universidade Federal do Rio de Janeiro. Centro de Tecnologia. Instituto de Química. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Núcleo de Pesquisas de Produtos Naturais. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Tecnologia. Instituto de Química. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Taxonomia, Bioquímica e Bioprospecção de Fungos. Rio de Janeiro, RJ. Brasil.Universidade Federal do Rio de Janeiro. Centro de Tecnologia. Instituto de Química. 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dc.title.pt_BR.fl_str_mv Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
title Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
spellingShingle Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
Almeida, Márcia R.
isatinas
Metodologia Sandmeyer
separação de isômeros
cromatografia de contra-corrente
isatins
Sandmeyer methodology
isomers separation
counter-current chromatography
title_short Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
title_full Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
title_fullStr Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
title_full_unstemmed Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
title_sort Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology
author Almeida, Márcia R.
author_facet Almeida, Márcia R.
Leitão, Gilda G.
Silva, Bárbara V.
Barbosa, Jussara P.
Pinto, Angelo C.
author_role author
author2 Leitão, Gilda G.
Silva, Bárbara V.
Barbosa, Jussara P.
Pinto, Angelo C.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Almeida, Márcia R.
Leitão, Gilda G.
Silva, Bárbara V.
Barbosa, Jussara P.
Pinto, Angelo C.
dc.subject.other.pt_BR.fl_str_mv isatinas
Metodologia Sandmeyer
separação de isômeros
cromatografia de contra-corrente
topic isatinas
Metodologia Sandmeyer
separação de isômeros
cromatografia de contra-corrente
isatins
Sandmeyer methodology
isomers separation
counter-current chromatography
dc.subject.en.pt_BR.fl_str_mv isatins
Sandmeyer methodology
isomers separation
counter-current chromatography
description A rapid and efficient method, using high-speed counter-current chromatography (HSCCC) technique, was developed for the separation of isomeric isatin derivatives, prepared following the Sandmeyer route. The biphasic solvent system composed of hexane:ethyl acetate:ethanol:water 1:0.5:0.5:1 (v/v/v/v) was used for all separations.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2018-04-10T13:55:31Z
dc.date.available.fl_str_mv 2018-04-10T13:55:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ALMEIDA, Márcia R. et al. Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology. J. Braz. Chem. Soc., v.21, n.4, p.764-769, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/25720
dc.identifier.issn.pt_BR.fl_str_mv 0103-5053
dc.identifier.eissn.none.fl_str_mv 1678-4790
identifier_str_mv ALMEIDA, Márcia R. et al. Counter-Current Chromatography Separation of Isatin Derivatives using the Sandmeyer Methodology. J. Braz. Chem. Soc., v.21, n.4, p.764-769, 2010.
0103-5053
1678-4790
url https://www.arca.fiocruz.br/handle/icict/25720
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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