Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil

Detalhes bibliográficos
Autor(a) principal: Oliveira, Dayse Cury de Almeida
Data de Publicação: 2014
Outros Autores: Carvalho, Magda Oliveira Seixas, Nascimento, Valma Maria Lopes do, Villas-Bôas, Flávia Silva, Castro Filho, Bernardo Galvão, Gonçalves, Marilda de Souza
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8805
Resumo: Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Publica. Salvador, BA, Brasil.
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spelling Oliveira, Dayse Cury de AlmeidaCarvalho, Magda Oliveira SeixasNascimento, Valma Maria Lopes doVillas-Bôas, Flávia SilvaCastro Filho, Bernardo GalvãoGonçalves, Marilda de Souza2014-11-12T17:50:05Z2014-11-12T17:50:05Z2014OLIVEIRA, D. C. A. et al. Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil. Revista Brasileira de Hematologia e Hemoterapia, v. 36, n. 5, p. 340-344, 2014.1516-8484https://www.arca.fiocruz.br/handle/icict/8805dx.doi.org/10.1016/j.bjhh.2014.07.012engElsevier Editora LtdaSickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInstituto Brasileiro de Oftalmologia e Prevenção da Cegueira. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Publica. Salvador, BA, Brasil.Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Fundação de Hematologia e Hemoterapia do Estado da Bahia. Salvador, BA, Brasil.Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde Publica. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Universidade Federal da Bahia. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia do Sangue. Campinas, SP, Brasil.Objective: The aim of the present study was to characterize sickle cell disease retinopathyin children and teenagers from Bahia, the state in northeastern Brazil with the highestincidence and prevalence of sickle cell disease.Methods: A group of 51 sickle cell disease patients (36 hemoglobin SS and 15 hemoglobinSC) with ages ranging from 4 to 18 years was studied. Ophthalmological examinations wereperformed in all patients. Moreover, a fluorescein angiography was also performed in over10-year-old patients.Results: The most common ocular lesions were vascular tortuosity, which was found in nine(25%) hemoglobin SS patients, and black sunburst, in three (20%) hemoglobin SC patients.Peripheral arterial closure was observed in five (13.9%) hemoglobin SS patients and in three(13.3%) hemoglobin SC patients. Arteriovenous anastomoses were present in six (16.5%)hemoglobin SS patients and six (37.5%) hemoglobin SC patients. Neovascularization wasnot identified in any of the patients.Conclusions: This study supports the use of early ophthalmological examinations in youngsickle cell disease patients to prevent the progression of retinopathy to severe disease andfurther blindness.Sickle cell anemiaDisease SCRetinopathyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8805/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALOliveira DCA Sickle cell....pdfOliveira DCA Sickle cell....pdfapplication/pdf750288https://www.arca.fiocruz.br/bitstream/icict/8805/2/Oliveira%20DCA%20Sickle%20cell....pdf9815195b1eac2fedc51a30e9134231b1MD52TEXTOliveira DCA Sickle cell....pdf.txtOliveira DCA Sickle cell....pdf.txtExtracted texttext/plain16112https://www.arca.fiocruz.br/bitstream/icict/8805/3/Oliveira%20DCA%20Sickle%20cell....pdf.txt37db6669bad3e8f1d4a38a144d760e5fMD53icict/88052023-03-15 14:33:00.944oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
title Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
spellingShingle Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
Oliveira, Dayse Cury de Almeida
Sickle cell anemia
Disease SC
Retinopathy
title_short Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
title_full Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
title_fullStr Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
title_full_unstemmed Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
title_sort Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil
author Oliveira, Dayse Cury de Almeida
author_facet Oliveira, Dayse Cury de Almeida
Carvalho, Magda Oliveira Seixas
Nascimento, Valma Maria Lopes do
Villas-Bôas, Flávia Silva
Castro Filho, Bernardo Galvão
Gonçalves, Marilda de Souza
author_role author
author2 Carvalho, Magda Oliveira Seixas
Nascimento, Valma Maria Lopes do
Villas-Bôas, Flávia Silva
Castro Filho, Bernardo Galvão
Gonçalves, Marilda de Souza
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Dayse Cury de Almeida
Carvalho, Magda Oliveira Seixas
Nascimento, Valma Maria Lopes do
Villas-Bôas, Flávia Silva
Castro Filho, Bernardo Galvão
Gonçalves, Marilda de Souza
dc.subject.en.pt_BR.fl_str_mv Sickle cell anemia
Disease SC
Retinopathy
topic Sickle cell anemia
Disease SC
Retinopathy
description Instituto Brasileiro de Oftalmologia e Prevenção da Cegueira. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Publica. Salvador, BA, Brasil.
publishDate 2014
dc.date.accessioned.fl_str_mv 2014-11-12T17:50:05Z
dc.date.available.fl_str_mv 2014-11-12T17:50:05Z
dc.date.issued.fl_str_mv 2014
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, D. C. A. et al. Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil. Revista Brasileira de Hematologia e Hemoterapia, v. 36, n. 5, p. 340-344, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8805
dc.identifier.issn.none.fl_str_mv 1516-8484
dc.identifier.doi.none.fl_str_mv dx.doi.org/10.1016/j.bjhh.2014.07.012
identifier_str_mv OLIVEIRA, D. C. A. et al. Sickle cell disease retinopathy: characterization among pediatric and teenage patients from northeastern Brazil. Revista Brasileira de Hematologia e Hemoterapia, v. 36, n. 5, p. 340-344, 2014.
1516-8484
dx.doi.org/10.1016/j.bjhh.2014.07.012
url https://www.arca.fiocruz.br/handle/icict/8805
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier Editora Ltda
publisher.none.fl_str_mv Elsevier Editora Ltda
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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