Preventive therapy for HIV-associated tuberculosis

Detalhes bibliográficos
Autor(a) principal: Durovni, B.
Data de Publicação: 2018
Outros Autores: Cavalcante, S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/33879
Resumo: 2020-07-08
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spelling Durovni, B.Cavalcante, S.2019-07-08T14:39:32Z2019-07-08T14:39:32Z2018DUROVNI, Betina; CAVALCANTE, Solange. Preventive therapy for HIV-associated tuberculosis. Current Opinion in HIV and AIDS, v. 13, n. 6, p. 507-511, Nov. 2018.1746-630Xhttps://www.arca.fiocruz.br/handle/icict/3387910.1097/COH.00000000000005041746-6318engLippincott, Williams & WilkinsPreventive therapy for HIV-associated tuberculosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-07-08Fundação Oswaldo Cruz. Presidência. Centro de Estudos Estratégicos. Rio de Janeiro, RJ, Brasil / Federal University of Rio de Janeiro. Instituto de Doenças do Tórax. Rio de Janeiro, RJ, Brazil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia. Evandro Chagas. Rio de Janeiro, RJ, Brasil.Purpose of review: Tuberculosis (TB) remains the leading cause of death in people living with HIV (PLHIV) despite the achievements in antiretroviral therapy coverage. TB preventive therapy (TPT) has proved efficacy but has been neglected and poorly implemented. We reviewed recent publications and guidelines about TPT in PLHIV. Recent findings: High-quality studies showed that TPT has a durable effect, over 5 years, preventing TB and all-cause mortality. There is new evidence showing the noninferiority of shorter, rifamycin-based regimens of TPT increasing the options for treatment. Recent studies describing robust implementation in different settings showed promising results for feasibility, tolerance, retention, and cost-effectiveness. New WHO recommendations, unifying previous versions, have been released to guide countries implementation. Summary: New evidence support the scale up of TPT for PLHIV globally, further studies are needed to bring more evidence for specific populations, like pregnant women and for drug–drug interactions with antiretroviral agents.HIVLatent tuberculosis infectionTuberculosis preventive therapyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/33879/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Durovni_Betina_etal_INI_2018.pdfve_Durovni_Betina_etal_INI_2018.pdfapplication/pdf193954https://www.arca.fiocruz.br/bitstream/icict/33879/2/ve_Durovni_Betina_etal_INI_2018.pdf54d2dcd5be5247258f099c4d5116a98dMD52TEXTve_Durovni_Betina_etal_INI_2018.pdf.txtve_Durovni_Betina_etal_INI_2018.pdf.txtExtracted texttext/plain23307https://www.arca.fiocruz.br/bitstream/icict/33879/3/ve_Durovni_Betina_etal_INI_2018.pdf.txt787f44762873a86464b0e9eb9a46fa77MD53icict/338792021-03-24 16:32:33.977oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:33Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Preventive therapy for HIV-associated tuberculosis
title Preventive therapy for HIV-associated tuberculosis
spellingShingle Preventive therapy for HIV-associated tuberculosis
Durovni, B.
HIV
Latent tuberculosis infection
Tuberculosis preventive therapy
title_short Preventive therapy for HIV-associated tuberculosis
title_full Preventive therapy for HIV-associated tuberculosis
title_fullStr Preventive therapy for HIV-associated tuberculosis
title_full_unstemmed Preventive therapy for HIV-associated tuberculosis
title_sort Preventive therapy for HIV-associated tuberculosis
author Durovni, B.
author_facet Durovni, B.
Cavalcante, S.
author_role author
author2 Cavalcante, S.
author2_role author
dc.contributor.author.fl_str_mv Durovni, B.
Cavalcante, S.
dc.subject.en.pt_BR.fl_str_mv HIV
Latent tuberculosis infection
Tuberculosis preventive therapy
topic HIV
Latent tuberculosis infection
Tuberculosis preventive therapy
description 2020-07-08
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-07-08T14:39:32Z
dc.date.available.fl_str_mv 2019-07-08T14:39:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DUROVNI, Betina; CAVALCANTE, Solange. Preventive therapy for HIV-associated tuberculosis. Current Opinion in HIV and AIDS, v. 13, n. 6, p. 507-511, Nov. 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/33879
dc.identifier.issn.pt_BR.fl_str_mv 1746-630X
dc.identifier.doi.none.fl_str_mv 10.1097/COH.0000000000000504
dc.identifier.eissn.none.fl_str_mv 1746-6318
identifier_str_mv DUROVNI, Betina; CAVALCANTE, Solange. Preventive therapy for HIV-associated tuberculosis. Current Opinion in HIV and AIDS, v. 13, n. 6, p. 507-511, Nov. 2018.
1746-630X
10.1097/COH.0000000000000504
1746-6318
url https://www.arca.fiocruz.br/handle/icict/33879
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Lippincott, Williams & Wilkins
publisher.none.fl_str_mv Lippincott, Williams & Wilkins
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
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