Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma

Detalhes bibliográficos
Autor(a) principal: Quintella, Danielle Carvalho
Data de Publicação: 2017
Outros Autores: Campos-do-Carmo, Gabriella, Quintella, Leonardo Pereira, Cuzzi, Tullia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/34441
Resumo: Universidade Federal do Rio de Janeiro. School of Medicine. Department of Pathology. Rio de Janeiro, RJ, Brasil.
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spelling Quintella, Danielle CarvalhoCampos-do-Carmo, GabriellaQuintella, Leonardo PereiraCuzzi, Tullia2019-07-26T13:40:43Z2019-07-26T13:40:43Z2017QUINTELLA, Danielle Carvalho et al. Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma. Anais Brasileiros de Dermatologia, v. 92, n. 3, p. 375-378, 2017.0365-0596https://www.arca.fiocruz.br/handle/icict/3444110.1590/abd1806-4841.20175169engSociedade Brasileira de DermatologiaHistopathological diagnosis of small melanocytic lesions suspicious for malignant melanomainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. School of Medicine. Department of Pathology. Rio de Janeiro, RJ, Brasil.Instituto Nacional do Câncer. Dermatology Service. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Serviço de Anatomia Patológica. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. School of Medicine. Department of Pathology. Rio de Janeiro, RJ, Brasil.The concern about malignant skin neoplasms leads to the excision of smaller lesions. This study on small melanocytic lesions aims to evaluate the range of possible histopathological diagnoses, describe histopathological aspects, and assess the usefulness of serial histological sections. We performed a cross-sectional descriptive histopathological study examining 76 pigmented skin lesions up to 6 mm in diameter. Histopathological diagnoses included atypical melanocytic nevi (n=38), common melanocytic nevi (n=18), atypical lentiginous melanocytic hyperplasia with architectural features of atypical melanocytic nevi (n=7), lentigo simplex (n=2), and malignant melanoma (n=1). Ten cases were non-diagnostic. Cytological atypia was not an exclusive finding of atypical lesions. Examination of serial sections did not change histopathological impression. Early detection of malignant melanoma is important, but clinical and dermoscopy exams may be leading to the resection of a great number of benign lesions. Strict attention to histopathological criteria results in a large number of non-diagnostic cases.DiagnosisMelanomaNevi and melanomasPathologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/34441/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Quintella_Danielle_etal_INI_2017.pdfve_Quintella_Danielle_etal_INI_2017.pdfapplication/pdf449291https://www.arca.fiocruz.br/bitstream/icict/34441/2/ve_Quintella_Danielle_etal_INI_2017.pdfd7d7b9ebf1196c9cb6ed86a6d55290adMD52TEXTve_Quintella_Danielle_etal_INI_2017.pdf.txtve_Quintella_Danielle_etal_INI_2017.pdf.txtExtracted texttext/plain21500https://www.arca.fiocruz.br/bitstream/icict/34441/3/ve_Quintella_Danielle_etal_INI_2017.pdf.txt56f365a68b018ea2ee6b5d2623a9ad1eMD53icict/344412019-07-27 02:03:02.282oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-07-27T05:03:02Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
title Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
spellingShingle Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
Quintella, Danielle Carvalho
Diagnosis
Melanoma
Nevi and melanomas
Pathology
title_short Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
title_full Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
title_fullStr Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
title_full_unstemmed Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
title_sort Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma
author Quintella, Danielle Carvalho
author_facet Quintella, Danielle Carvalho
Campos-do-Carmo, Gabriella
Quintella, Leonardo Pereira
Cuzzi, Tullia
author_role author
author2 Campos-do-Carmo, Gabriella
Quintella, Leonardo Pereira
Cuzzi, Tullia
author2_role author
author
author
dc.contributor.author.fl_str_mv Quintella, Danielle Carvalho
Campos-do-Carmo, Gabriella
Quintella, Leonardo Pereira
Cuzzi, Tullia
dc.subject.en.pt_BR.fl_str_mv Diagnosis
Melanoma
Nevi and melanomas
Pathology
topic Diagnosis
Melanoma
Nevi and melanomas
Pathology
description Universidade Federal do Rio de Janeiro. School of Medicine. Department of Pathology. Rio de Janeiro, RJ, Brasil.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2019-07-26T13:40:43Z
dc.date.available.fl_str_mv 2019-07-26T13:40:43Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv QUINTELLA, Danielle Carvalho et al. Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma. Anais Brasileiros de Dermatologia, v. 92, n. 3, p. 375-378, 2017.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/34441
dc.identifier.issn.pt_BR.fl_str_mv 0365-0596
dc.identifier.doi.pt_BR.fl_str_mv 10.1590/abd1806-4841.20175169
identifier_str_mv QUINTELLA, Danielle Carvalho et al. Histopathological diagnosis of small melanocytic lesions suspicious for malignant melanoma. Anais Brasileiros de Dermatologia, v. 92, n. 3, p. 375-378, 2017.
0365-0596
10.1590/abd1806-4841.20175169
url https://www.arca.fiocruz.br/handle/icict/34441
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
publisher.none.fl_str_mv Sociedade Brasileira de Dermatologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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