A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery

Detalhes bibliográficos
Autor(a) principal: Cardoso, Rafael M.
Data de Publicação: 2020
Outros Autores: Santos, Robson O. dos, Munoz, Rodrigo A. A., Garcia, Carlos D., Blanes, Lucas
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.3390/s20174909
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44267
Resumo: Universidade Federal de Uberlândia. Instituto de Química. Uberlândia, MG, Brasil.
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spelling Cardoso, Rafael M.Santos, Robson O. dosMunoz, Rodrigo A. A.Garcia, Carlos D.Blanes, Lucas2020-10-29T20:01:21Z2020-10-29T20:01:21Z2020CARDOSO, Rafael M. et al. A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery. Sensors. v. 20, n. 4909, p. 1-9, 2020.1424-8220https://www.arca.fiocruz.br/handle/icict/4426710.3390/s20174909porMDPIA multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte deliveryinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal de Uberlândia. Instituto de Química. Uberlândia, MG, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Ciências e Tecnologias Aplicadas em Saúde. Curitiba, PR, Brasil.Universidade Federal de Uberlândia. Instituto de Química. Uberlândia, MG, Brasil.Department of Chemistry. Clemson University. Clemson, USA.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Ciências e Tecnologias Aplicadas em Saúde. Curitiba, PR, Brasil.This article shows the development of a computer-controlled lab-on-a-chip device with three magnetohydrodynamic (MHD) pumps and a pneumatic valve. The chip was made of a stack of layers of polymethylmethacrylate (PMMA), cut using a laser engraver and thermally bonded. The MHD pumps were built using permanent magnets (neodymium) and platinum electrodes, all of them controlled by an Arduino board and a set of relays. The implemented pumps were able to drive solutions in the open channels with a flow rate that increased proportionally with the channel width and applied voltage. To address the characteristic low pressures generated by this kind of pump, all channels were interconnected. Because the electrodes were immersed in the electrolyte, causing electrolysis and pH variations, the composition and ionic strength of the electrolyte solution were controlled. Additionally, side structures for releasing bubbles were integrated. With this multi-pump and valve solution, the device was used to demonstrate the possibility of performing an injection sequence in a system that resembles a traditional flow injection analysis system. Ultimately, the results demonstrate the possibility of performing injection sequences using an array of MHD pumps that can perform fluid handling in the 0–5 µL s−1 range.MagnetohydrodynamicHydrodynamic ModelsLab-On-A-Chip DevicesFlow Injection AnalysisModelos HidrodinámicosDispositivos Laboratorio en un ChipAnálisis de Inyección de FlujoModèles HydrodynamiquesLaboratoires sur pucesAnalyse par injection en flux continuModelos HidrodinâmicosDispositivos Lab-On-A-ChipAnálise de Injeção de Fluxoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
title A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
spellingShingle A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
Cardoso, Rafael M.
Magnetohydrodynamic
Hydrodynamic Models
Lab-On-A-Chip Devices
Flow Injection Analysis
Modelos Hidrodinámicos
Dispositivos Laboratorio en un Chip
Análisis de Inyección de Flujo
Modèles Hydrodynamiques
Laboratoires sur puces
Analyse par injection en flux continu
Modelos Hidrodinâmicos
Dispositivos Lab-On-A-Chip
Análise de Injeção de Fluxo
title_short A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
title_full A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
title_fullStr A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
title_full_unstemmed A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
title_sort A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery
author Cardoso, Rafael M.
author_facet Cardoso, Rafael M.
Santos, Robson O. dos
Munoz, Rodrigo A. A.
Garcia, Carlos D.
Blanes, Lucas
author_role author
author2 Santos, Robson O. dos
Munoz, Rodrigo A. A.
Garcia, Carlos D.
Blanes, Lucas
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Cardoso, Rafael M.
Santos, Robson O. dos
Munoz, Rodrigo A. A.
Garcia, Carlos D.
Blanes, Lucas
dc.subject.en.pt_BR.fl_str_mv Magnetohydrodynamic
Hydrodynamic Models
Lab-On-A-Chip Devices
Flow Injection Analysis
topic Magnetohydrodynamic
Hydrodynamic Models
Lab-On-A-Chip Devices
Flow Injection Analysis
Modelos Hidrodinámicos
Dispositivos Laboratorio en un Chip
Análisis de Inyección de Flujo
Modèles Hydrodynamiques
Laboratoires sur puces
Analyse par injection en flux continu
Modelos Hidrodinâmicos
Dispositivos Lab-On-A-Chip
Análise de Injeção de Fluxo
dc.subject.es.pt_BR.fl_str_mv Modelos Hidrodinámicos
Dispositivos Laboratorio en un Chip
Análisis de Inyección de Flujo
dc.subject.fr.pt_BR.fl_str_mv Modèles Hydrodynamiques
Laboratoires sur puces
Analyse par injection en flux continu
dc.subject.decs.pt_BR.fl_str_mv Modelos Hidrodinâmicos
Dispositivos Lab-On-A-Chip
Análise de Injeção de Fluxo
description Universidade Federal de Uberlândia. Instituto de Química. Uberlândia, MG, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-10-29T20:01:21Z
dc.date.available.fl_str_mv 2020-10-29T20:01:21Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CARDOSO, Rafael M. et al. A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery. Sensors. v. 20, n. 4909, p. 1-9, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44267
dc.identifier.issn.pt_BR.fl_str_mv 1424-8220
dc.identifier.doi.none.fl_str_mv 10.3390/s20174909
identifier_str_mv CARDOSO, Rafael M. et al. A multi-pump magnetohydrodynamics lab-on-a-chip device for automated flow control and analyte delivery. Sensors. v. 20, n. 4909, p. 1-9, 2020.
1424-8220
10.3390/s20174909
url https://www.arca.fiocruz.br/handle/icict/44267
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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