Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/31526 |
Resumo: | University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil. |
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Barreto, Luis Paulo DinizSantos, Marcela Melo dosGomes, Bruno da SilvaLamas, Cristiane da CruzSilva, Denise Gomes daSilva-Boghossian, Carina MacielSoares, Léo GuimarãesFalabella, Marcio Eduardo Vieira2019-02-11T11:19:52Z2019-02-11T11:19:52Z2016BARRETO, Luis Paulo Diniz et al. Periodontal conditions in Human Immunodeficiency Virus–Positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro. Journal of Periodontology, v. 87, n. 4, p. 338-345, Apr. 2016.0022-3492https://www.arca.fiocruz.br/handle/icict/3152610.1902/jop.2015.150345engAmerican Academy of PeriodontologyPeriodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiroinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversity of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Medicine. Department of Infectious Disease. Duque de Caxias, Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Medicine. Department of Infectious Disease. Duque de Caxias, Rio de Janeiro, RJ, Brazil / Oswaldo Cruz Foundation. National Institute of Infectology Evandro Chagas. Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil.University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil.Federal University of Juiz de Fora. Department of Periodontics. Juiz de Fora, MG, Brazil.Background: The aim of this study is to evaluate the periodontal status and the presence of opportunistic oral lesions in human immunodeficiency virus–positive (HIV+) patients under highly active antiretroviral therapy (HAART) and their association with cluster of differentiation (CD)4+ and CD4+ nadir T-cell counts and viral load levels. Methods: Clinical periodontal parameters and the presence of opportunistic oral lesions along with records of CD4+ counts and viral load levels were evaluated in 29 individuals (16 females; mean age: 42.7 years) with previous serologic diagnosis of HIV, from the acquired immunodeficiency syndrome program of the Health Center of Duque de Caxias, Rio de Janeiro, Brazil. Results: All individuals presented gingivitis or periodontitis. A higher non-significant prevalence of periodontitis was found in smokers (93.8%) compared with non-smokers (76.9%). A significant weak positive correlation was observed between CD4+ counts and missing teeth (r = 0.380, P <0.05), CD4+nadir and periodontal diagnosis (r = 0.418, P <0.005), and CD4+ nadir and moderate probing depth (PD) (r = 0.424, P <0.05). When only non-smokers were analyzed, a significant moderate positive association was found between viral load and moderate clinical attachment level (CAL) (r = 0.638, P <0.05), CD4+ nadir and diagnosis (r = 0.586, P <0.05), and CD4+ nadir and moderate CAL (r = 0.680, P <0.05). Analysis considering only smokers found no correlations between serologic parameters and demographic or clinical parameters. Conclusions: The current investigation demonstrates that HIV+ individuals under HAART presents a high prevalence of mild to moderate periodontal disease. Viral load levels, CD4+ nadir, and CD4+ counts may present a weak to moderate correlation to the number of missing teeth, periodontal diagnosis, moderate PD, and moderate CAL, which may also reflect some effect of these systemic conditions on the periodontal status.Antiretroviral therapyHighly activeCD4-positive T-lymphocytesHIVPeriodontal diseasesViral loadinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31526/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Barreto_Luis_etal_INI_2016.pdfve_Barreto_Luis_etal_INI_2016.pdfapplication/pdf538578https://www.arca.fiocruz.br/bitstream/icict/31526/2/ve_Barreto_Luis_etal_INI_2016.pdf0e7f76f2ddd1ca57c79567f795fcdf7aMD52TEXTve_Barreto_Luis_etal_INI_2016.pdf.txtve_Barreto_Luis_etal_INI_2016.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| title |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| spellingShingle |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro Barreto, Luis Paulo Diniz Antiretroviral therapy Highly active CD4-positive T-lymphocytes HIV Periodontal diseases Viral load |
| title_short |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| title_full |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| title_fullStr |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| title_full_unstemmed |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| title_sort |
Periodontal conditions in Human Immunodeficiency Virus-positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro |
| author |
Barreto, Luis Paulo Diniz |
| author_facet |
Barreto, Luis Paulo Diniz Santos, Marcela Melo dos Gomes, Bruno da Silva Lamas, Cristiane da Cruz Silva, Denise Gomes da Silva-Boghossian, Carina Maciel Soares, Léo Guimarães Falabella, Marcio Eduardo Vieira |
| author_role |
author |
| author2 |
Santos, Marcela Melo dos Gomes, Bruno da Silva Lamas, Cristiane da Cruz Silva, Denise Gomes da Silva-Boghossian, Carina Maciel Soares, Léo Guimarães Falabella, Marcio Eduardo Vieira |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Barreto, Luis Paulo Diniz Santos, Marcela Melo dos Gomes, Bruno da Silva Lamas, Cristiane da Cruz Silva, Denise Gomes da Silva-Boghossian, Carina Maciel Soares, Léo Guimarães Falabella, Marcio Eduardo Vieira |
| dc.subject.en.pt_BR.fl_str_mv |
Antiretroviral therapy Highly active CD4-positive T-lymphocytes HIV Periodontal diseases Viral load |
| topic |
Antiretroviral therapy Highly active CD4-positive T-lymphocytes HIV Periodontal diseases Viral load |
| description |
University of Grande Rio. Faculty of Dentistry. Department of Periodontics. Duque de Caxias, Rio de Janeiro, RJ, Brazil. |
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2016 |
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2016 |
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2019-02-11T11:19:52Z |
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2019-02-11T11:19:52Z |
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BARRETO, Luis Paulo Diniz et al. Periodontal conditions in Human Immunodeficiency Virus–Positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro. Journal of Periodontology, v. 87, n. 4, p. 338-345, Apr. 2016. |
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https://www.arca.fiocruz.br/handle/icict/31526 |
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0022-3492 |
| dc.identifier.doi.none.fl_str_mv |
10.1902/jop.2015.150345 |
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BARRETO, Luis Paulo Diniz et al. Periodontal conditions in Human Immunodeficiency Virus–Positive patients under highly active antiretroviral therapy from a metropolitan area of Rio de Janeiro. Journal of Periodontology, v. 87, n. 4, p. 338-345, Apr. 2016. 0022-3492 10.1902/jop.2015.150345 |
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American Academy of Periodontology |
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American Academy of Periodontology |
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